THYROID ANALYTE MEASUREMENT
First Claim
Patent Images
1. A non-radioisotopic method of measuring thyroid analytes comprising:
- a. obtaining a patient sample from a canine species;
b. incubating the sample with a non-radioisotopic label detectant; and
c. measuring T3 in the sample of the canine species using a first non-radioisotopic label as the detectant,d. measuring T4 in the sample of the canine species using a second non-radioisotopic label as the detectant, ande. separately measuring Free T3 using the first non-radioisotopic label as the detectant, and measuring Free T4 in the sample of the canine species using the second non-radioisotopic label as the detectant.
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Abstract
A non-radioisotopic method measures Free T3 and/or Free T4 in a sample of a non-human species, which can be a canine.
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Citations
17 Claims
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1. A non-radioisotopic method of measuring thyroid analytes comprising:
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a. obtaining a patient sample from a canine species; b. incubating the sample with a non-radioisotopic label detectant; and c. measuring T3 in the sample of the canine species using a first non-radioisotopic label as the detectant, d. measuring T4 in the sample of the canine species using a second non-radioisotopic label as the detectant, and e. separately measuring Free T3 using the first non-radioisotopic label as the detectant, and measuring Free T4 in the sample of the canine species using the second non-radioisotopic label as the detectant. - View Dependent Claims (7, 8, 9, 10, 11, 12)
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2-4. -4. (canceled)
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5. A non-radioisotopic method of measuring thyroid analytes comprising:
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a. obtaining a patient sample from a canine species; b. incubating the sample with a non-radioisotopic label detectant; c. measuring Free T4 in the sample of the canine species using the non-radioisotopic label as the detectant, and d. measuring T4 in the sample; and e. wherein a r-squared value of T4 relative to Free T4 is between about 0.75 and about 0.99.
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6. (canceled)
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13. A non-radioisotopic method of measuring thyroid analyte comprising:
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a. obtaining a patient sample from a canine species; b. incubating the sample with a non-radioisotopic label detectant; c. measuring Free T4 in the sample of the canine species using the non-radioisotopic label as the detectant, and d. employing direct chemiluminescence, and including a bioluminescent detector and microparticles as a solid phase for immobilizing FreeT4. - View Dependent Claims (14, 15, 16, 17)
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Specification