SYSTEM AND METHOD FOR DETERMINING INTRINSIC AV INTERVAL TIMING

• US 20110112596A1
• Filed: 01/11/2011
• Published: 05/12/2011
• Est. Priority Date: 06/15/2006
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Belk, Paul A., Sheldon, Todd J., Sweeney, Michael O.
• Granted Patent: US 8,032,216 B2
• Time in Patent Office: Days
• US Class Current: 607/25
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3682 with a variable atrioventricular delay

Abstract

An atrial based pacing protocol promotes intrinsic conduction. An entire cardiac cycle is monitored for ventricular activity and permitted to lapse with ventricular activity. Ventricular pacing is available in a cardiac cycle immediately subsequent to such a skipped beat. When monitoring for intrinsic ventricular events, an event is expected within a given window. If no such event is detected, the cardiac cycle is truncated, leading to a shorter cycle that is devoid of ventricular activity. The subsequent cycle has a high likelihood of a ventricular sensed event and a greater than normal AV interval is provided prior to pacing.

Claims

1. An implantable medical device, comprising:

means for pacing at an atrial test rate;

means for sensing to determine if ventricular conduction occurs;

means for measuring the AV delay if conduction occurred;

means for recording the AV delay as corresponding to the test rate in the implantable medical device (IMD);

means for increasing the test rate by a predetermined increment and repeating the steps of sensing measuring and recording;

means for operating the IMD according to a ventricular pacing protocol (VPP);

means for sensing a premature ventricular contraction (PVC) in a first cardiac cycle;

means for measuring a duration of a first ventricular interval from a ventricular event immediately preceding the PVC to the PVC;

means for calculating a duration of a second ventricular interval to occur from the PVC to a target ventricular sensed event; and

means for modifying atrial timing in the first cardiac cycle to effect the second ventricular interval, wherein the modification to atrial timing is only made if data recorded in the memory indicates successful AV conduction at the modified atrial rate.

2. The device of claim 1, wherein the second ventricular interval occurs without ventricular pacing.

3. The device of claim 1, comprising means for modifying atrial timing in subsequent consecutive cycles until a resultant V-V interval is substantially equal to a V-V interval prior to the first ventricular interval.

4. The device of claim 3, wherein the modification of atrial timing in subsequent consecutive cycles results in a smoothing of the resultant V-V intervals.

5. The device of claim 1, wherein calculating the duration of the second ventricular interval includes adding a constant to the duration of the first ventricular interval.

6. The device of claim 5, wherein the constant is selected from a table and the table includes constant values for corresponding ventricular intervals.

7. The device of claim 1, wherein calculating the duration of the second ventricular interval includes increasing the first ventricular interval by a predetermined percentage.

8. The device of claim 1, further comprising:

means for sensing for atrial refractory events; and

means for adding a predetermined value to the modified atrial timing if an atrial refractory event is sensed.

9. The device of claim 1, further comprising:

means for setting a first AV interval for delivering a ventricular backup pacing pulse following an A-A interval devoid of a sensed ventricular event according to the VPP;

means for setting a second AV interval for delivering a ventricular pacing pulse following a truncated A-A interval as modified to effect the second ventricular interval wherein the second AV interval is longer than the first AV interval.

10. The device of claim 1, wherein modifying the atrial timing includes determining an AV interval that would result in the target sensed ventricular event and delivering an atrial pacing pulse at so that the atrial pacing pulse initiated the AV interval.

11. An implantable medical device, comprising:

an atrial pulse generator providing atrial pacing at atrial test rates;

a ventricular sense amplifier responsive to occurrences of ventricular conduction following the pacing at atrial test rates;

timing circuitry measuring the AV delay if conduction occurred following the pacing at atrial test rates;

a recorder recording the measured AV delays as corresponding to the test rates in the implantable medical device (IMD);

wherein the atrial pulse generator further provides atrial pacing at non-testing rates;

wherein the ventricular sense amplifier is further responsive to premature ventricular contractions (PVCs) in given cardiac cycles during pacing at the non-testing rates;

wherein the timing circuitry further measures a durations of first ventricular intervals extending between ventricular events immediately preceding the PVCs to the PVCs in the given cardiac cycles;

control circuitry calculating a duration of a second ventricular intervals extending from the PVCs to desired ventricular sensed events; and

control circuitry modifying the non-testing rates in the given cardiac cycles to effect the second ventricular interval, wherein the modification to atrial the non-testing rate is only made if data recorded in the device indicates AV conduction occurred at the test rate corresponding to the modified non-testing rate.

12. The device of claim 11, wherein the second ventricular interval occurs without ventricular pacing.

13. The device of claim 11, wherein the control circuitry further modifies non-testing pacing rates over subsequent consecutive cardiac cycles until a resultant V-V interval is substantially equal to a V-V interval prior to the first ventricular interval.

14. The device of claim 13, wherein the modification of the non-testing pacing rates in subsequent consecutive cardiac cycles results in a smoothing of the resultant V-V intervals.

15. The device of claim 11, wherein calculating the duration of the second ventricular interval includes adding a constant to the duration of the first ventricular interval.

16. The device of claim 15, wherein the constant is selected from a table and the table includes constant values for corresponding ventricular intervals.

17. The device of claim 11, wherein calculating the duration of the second ventricular interval includes increasing the first ventricular interval by a predetermined percentage.

18. The device of claim 11, further comprising:

an atrial sense amplifier responsive to atrial refractory events; and

wherein the control circuitry adds a predetermined value to the modified non-test pacing interval if an atrial refractory event is sensed.

19. The device of claim 11, further comprising:

a ventricular pulse generator providing ventricular pacing;

an AV delay timer setting a first AV interval triggering the ventricular pulse generator to provide ventricular pacing following an unmodified non-test atrial pacing interval devoid of sensed ventricular events; and

wherein the AV delay timer further sets a second AV interval triggering the ventricular pulse generator to provide ventricular pacing following a modified non-test atrial pacing interval devoid of sensed ventricular events wherein the second AV interval is longer than the first AV interval.