APPARATUS FOR DETECTING VOLATILE ORGANIC COMPOUNDS AND RELATED METHODS
First Claim
1. An apparatus for detecting one or more volatile organic compounds (VOCs) comprising:
- a primary electrode;
one or more particles coupled to the primary electrode, wherein the one or more particles are coupled to one or more enzymes that are capable of undergoing a redox reaction with at least one VOC; and
a reference electrode,wherein the apparatus is configured to measure current or voltage generated between the primary electrode and the reference electrode in response to the redox reaction.
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Abstract
Disclosed are apparatuses for detecting one or more volatile organic compounds (VOCs). The apparatuses include a primary electrode and a reference electrode. One or more particles are coupled to the primary electrode and the one or more particles are coupled to one or more enzymes that are capable of undergoing a redox reaction with at least one VOC. The apparatus is configured to measure current or voltage generated between the primary electrode and the reference electrode in response to the redox reaction. The apparatuses can detect a variety of VOCs, including VOCs associated with lung cancer. Also disclosed are biosensor systems including the apparatuses and methods of using the biosensor systems.
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Citations
20 Claims
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1. An apparatus for detecting one or more volatile organic compounds (VOCs) comprising:
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a primary electrode; one or more particles coupled to the primary electrode, wherein the one or more particles are coupled to one or more enzymes that are capable of undergoing a redox reaction with at least one VOC; and a reference electrode, wherein the apparatus is configured to measure current or voltage generated between the primary electrode and the reference electrode in response to the redox reaction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method for detecting a volatile organic compound (VOC) in an assayed sample, the method comprising:
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(a) introducing the sample to be assayed into the reaction cell of the biosensor comprising;
(i) a reaction cell with a primary electrode;
one or more particles coupled to the primary electrode, wherein the one or more particles are coupled to one or more enzymes that are capable of undergoing a redox reaction with at least one VOC; and
a reference electrode, and (ii) a detector configured to measure current or voltage generated between the primary electrode and the reference electrode in response to the redox reaction, and(b) measuring the current or voltage generated between the primary electrode and the reference electrode.
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Specification