HYPOGLYCEMIC TREATMENT METHODS AND SYSTEMS

• US 20110118578A1
• Filed: 11/17/2009
• Published: 05/19/2011
• Est. Priority Date: 11/17/2009
• Status: Abandoned Application

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Operations Incorporated (Roche Holding AG)
• Inventors: Timmerman, Robert David
• Application Number:
  US12/620,202
• Publication Number:
  US 20110118578A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2202/0486 Glucose
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 2205/582 by tactile feedback
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

A system for treating hypoglycemia includes a continuous blood glucose monitor that monitors blood glucose levels of a patient on a continuous basis over a period of time. An alarm and injector apparatus is configured to be worn by the patient and includes a glucagon delivery mechanism for automatically delivering glucagon to the patient if a hypoglycemic condition is detected using the continuous blood glucose monitor.

Claims

1. A method of treating hypoglycemia, comprising:

detecting a hypoglycemic condition using a continuous blood glucose monitor that monitors blood glucose levels of a patient on a continuous basis over a period of time;

providing an alarm alerting of the hypoglycemic condition; and

delivering glucagon to the patient using an alarm and injector apparatus comprising a glucagon delivery mechanism for delivering glucagon to the patient.

2. The method of claim 1 further comprising providing an alarm signal to the alarm and injector apparatus in response to detecting the hypoglycemic condition.

3. The method of claim 2 further comprising determining when the blood glucose level of the patient falls below a predetermined level.

4. The method of claim 3, wherein the alarm signal is provided from the continuous blood glucose monitor to the alarm and injector apparatus when the blood glucose level of the patient falls below the predetermined level.

5. The method of claim 3, wherein the alarm signal is provided from a blood glucose meter to the alarm and injector apparatus when the blood glucose level of the patient falls below the predetermined level.

6. The method of claim 2, wherein the alarm and injector apparatus includes a controller controlling an alarm mechanism providing the alarm.

7. The method of claim 6, wherein, after the step of providing the alarm, the controller looking for a patient-initiated input signal provided using an input mechanism within a predetermined time period.

8. The method of claim 7, wherein if the patient-initiated input signal is not received by the controller within the predetermined time period, the controller actuating the glucagon delivery mechanism.

9. A method of treating hypoglycemia, comprising:

detecting a hypoglycemic condition using a continuous blood glucose monitor that monitors blood glucose levels of a patient on a continuous basis over a period of time;

providing a first alarm signal to an alarm and injector apparatus worn by the patient if the hypoglycemic condition is above a predetermined blood glucose level;

providing a second alarm signal to the alarm and injector apparatus worn by the patient if the hypoglycemic condition is below the predetermined blood glucose level; and

providing an alarm using the alarm and injector apparatus in response to one or both of the first alarm signal and the second alarm signal, the alarm and injector apparatus comprising a glucagon delivery mechanism for delivering glucagon to the patient.

10. The method of claim 9 further comprising delivering glucagon using the glucagon delivery mechanism upon receipt of the second alarm signal by the alarm and injector apparatus.

11. The method of claim 10, wherein the step of delivering the glucagon is provided automatically if the alarm is not acknowledged within a preselected period of time.

12. The method of claim 10, wherein the step of delivering the glucagon is initiated manually.

13. The method of claim 9, wherein the first alarm signal and the second alarm signal are provided by the continuous blood glucose monitor.

14. The method of claim 9, wherein the first alarm signal and the second alarm signal are provided by a blood glucose meter receiving blood glucose information from the continuous blood glucose monitor.

15. A system for treating hypoglycemia, comprising:

a continuous blood glucose monitor that monitors blood glucose levels of a patient on a continuous basis over a period of time; and

an alarm and injector apparatus configured to be worn by the patient and including a glucagon delivery mechanism for automatically delivering glucagon to the patient if a hypoglycemic condition is detected using the continuous blood glucose monitor.

16. The system of claim 15, wherein the continuous blood glucose monitor comprises a transmitter for transmitting an alarm signal to the alarm and injector apparatus if a hypoglycemic condition is detected.

17. The system of claim 16 further comprising a blood glucose meter configured to receive blood glucose information from the continuous blood glucose monitor.

18. The system of claim 17, wherein the blood glucose meter comprises a transmitter for transmitting an alarm signal to the alarm and injector apparatus if a hypoglycemic condition is detected.

19. The system of claim 15, wherein the alarm and injector apparatus further includes an insulin delivery mechanism for use in delivering insulin to the patient.