ELLIPTICAL DEVICE FOR TREATING AFTERLOAD

• US 20110118773A1
• Filed: 12/02/2010
• Published: 05/19/2011
• Est. Priority Date: 07/25/2005
• Status: Abandoned Application

• Current Assignee: Rainbow Medical Ltd.
• Original Assignee: Rainbow Medical Ltd.
• Inventors: Dagan, Amir, Hanani, Nitai, Gross, Yossi
• Application Number:
  US12/959,126
• Publication Number:
  US 20110118773A1
• Time in Patent Office: Days
• US Class Current: 606/194
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2230/0008 elliptical or oval
• CPC Class Codes: A61M 2025/0681 Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube
• CPC Class Codes: A61M 2025/09183 having tools at the distal tip

Abstract

Apparatus and methods are provided, including an elongate element that is inserted into a subject'"'"'s artery via a catheter, the catheter being configured to be withdrawn from the artery subsequent to the insertion. Expandable elements are disposed on the elongate element, the expandable elements comprising respective distal tips that are substantially aligned with the elongate element. During insertion of the elongate element via the catheter, the expandable elements are in contracted states thereof. In response to the withdrawal of the catheter from the artery, the expandable elements cause the artery to change a shape thereof, by the expandable elements expanding such that the distal tips of the expandable elements contact respective contact points on the wall of the artery. Subsequently, the distal tips of the expandable elements are freed from the contact points upon pulling of the elongate element. Other embodiments are also described.

Claims

1. Apparatus, comprising:

a catheter configured to be inserted into an artery of a subject;

an elongate element configured to be inserted into the subject'"'"'s artery via the catheter, the catheter being configured to be withdrawn from the artery subsequent to the insertion of the elongate element into the artery; and

a plurality of expandable elements disposed on the elongate element, the expandable elements comprising respective distal tips that are substantially aligned with the elongate element, the expandable elements being configured;

during insertion of the elongate element via the catheter, to be in contracted states thereof,

in response to the withdrawal of the catheter from the artery, to cause the artery to change a shape thereof, by the expandable elements expanding, the expansion of the expandable elements causing the distal tips of the expandable elements to contact respective contact points on the wall of the artery, and

subsequently, for the distal tips of the expandable elements to be freed from their contact points with the wall of the artery upon pulling of the elongate element.

2. The apparatus according to claim 1, wherein the expandable elements are configured to be withdrawn from the artery by pulling the elongate element proximally.

3. The apparatus according to claim 1, wherein the expandable elements are configured to be withdrawn from the artery by advancing a catheter over the elongate element, and, subsequently, removing the catheter from the artery with the elongate element disposed inside the catheter.

4. The apparatus according to claim 1, wherein the expandable elements are configured to cause the artery to change the shape thereof by causing the artery to assume a first cross-sectional shape during a first phase of a cardiac cycle, and a second cross-sectional shape during a second phase of the cardiac cycle.

5. The apparatus according to claim 4, wherein the expandable elements are configured to cause an end-diastolic cross-sectional area of the artery to be 5-30 percent lower than the end-diastolic cross-sectional area of the artery in the absence of the expandable elements, by causing the artery to have the first and second cross-sectional shapes.

6. The apparatus according to claim 4, wherein the expandable elements are configured to cause an end-diastolic cross-sectional area of the artery to be 30-60 percent lower than the end-diastolic cross-sectional area of the artery in the absence of the expandable elements, by causing the artery to have the first and second cross-sectional shapes.

7. The apparatus according to claim 4, wherein the expandable elements are configured to cause an end-diastolic cross-sectional area of the artery to be 60-90 percent lower than the end-diastolic cross-sectional area of the artery in the absence of the expandable elements, by causing the artery to have the first and second cross-sectional shapes.

8. The apparatus according to claim 4, wherein the expandable elements are configured to cause an end-diastolic cross-sectional area of the artery to be more than 90 percent lower than an end-diastolic cross-sectional area of the artery in the absence of the expandable elements, by causing the artery to have the first and second cross-sectional shapes.

9. The apparatus according to claim 4, wherein the expandable elements are configured to cause the artery to have the first and second elliptical cross-sectional shapes, a ratio of (a) a major axis of the artery when assuming the first cross-sectional elliptical shape at end-diastole to (b) a major axis of the artery when assuming the second cross-sectional elliptical shape at end-diastole being between 1.1 and 1.5.

10. The apparatus according to claim 4, wherein the expandable elements are configured to cause the artery to assume the first and second shapes, a cross-sectional area of the artery when the artery assumes the second shape being greater than a cross-sectional area of the artery when the artery assumes the first shape.

11. The apparatus according to claim 10, wherein the expandable elements are configured to cause the artery to assume the first and second cross-sectional shapes, a cross-sectional area of the artery when the artery assumes the first cross-sectional shape being between 10 and 30 percent less than a cross-sectional area of the artery when the artery assumes the second cross-sectional shape.

12. A method, comprising:

inserting a catheter into an artery of a subject;

inserting an elongate element into the subject'"'"'s artery via the catheter, a plurality of expandable elements being disposed on the elongate element, and being in contracted states thereof during the insertion of the elongate element via the catheter;

subsequent to the insertion of the elongate element into the artery changing a shape of the artery, by expanding the expandable elements against respective contact points on the artery wall, by withdrawing the catheter; and

,

subsequently, freeing the expandable elements from their contact points with the wall of the artery by pulling the elongate element.

13. The method according to claim 12, further comprising determining a native compliance of the subject'"'"'s artery, and in response to the determining, selecting elements to be used as the expandable elements.

14. The method according to claim 12, wherein freeing the expandable elements from their contact points comprises advancing a catheter over the elongate element, and, subsequently, removing the catheter from the artery with the elongate element disposed inside the catheter.

15. The method according to claim 12, wherein changing the shape of the artery comprises causing the artery to assume a first cross-sectional shape during a first phase of a cardiac cycle, and a second cross-sectional shape during a second phase of the cardiac cycle.

16. The method according to claim 15, wherein changing the shape of the artery comprises causing an end-diastolic cross-sectional area of the artery to be 5-30 percent lower than the end-diastolic cross-sectional area of the artery in the absence of the expandable elements.

17. The method according to claim 15, wherein changing the shape of the artery comprises causing an end-diastolic cross-sectional area of the artery to be 30-60 percent lower than the end-diastolic cross-sectional area of the artery in the absence of the expandable elements.

18. The method according to claim 15, wherein changing the shape of the artery comprises causing an end-diastolic cross-sectional area of the artery to be 60-90 percent lower than the end-diastolic cross-sectional area of the artery in the absence of the expandable elements.

19. The method according to claim 15, wherein changing the shape of the artery comprises causing an end-diastolic cross-sectional area of the artery to be more than 90 percent lower than an end-diastolic cross-sectional area of the artery in the absence of the expandable elements.

20. The method according to claim 15, wherein changing the shape of the artery comprises causing the artery to have the first and second elliptical cross-sectional shapes, a ratio of (a) a major axis of the artery when assuming the first cross-sectional elliptical shape at end-diastole to (b) a major axis of the artery when assuming the second cross-sectional elliptical shape at end-diastole being between 1.1 and 1.5.

21. The method according to claim 15, wherein changing the shape of the artery comprises causing the artery to assume the first and second shapes, a cross-sectional area of the artery when the artery assumes the second shape being greater than a cross-sectional area of the artery when the artery assumes the first shape.

22. The method according to claim 21, wherein changing the shape of the artery comprises causing the artery to assume the first and second cross-sectional shapes, a cross-sectional area of the artery when the artery assumes the first cross-sectional shape being between 10 and 30 percent less than a cross-sectional area of the artery when the artery assumes the second cross-sectional shape.