METHOD AND COMPOSITIONS FOR BIOFOULING DETERRENCE

• US 20110123477A1
• Filed: 03/24/2009
• Published: 05/26/2011
• Est. Priority Date: 03/24/2008
• Status: Active Grant

• Current Assignee: Clemson University
• Original Assignee: Clemson University
• Inventors: Gohad, Neeraj V., Metters, Andrew, Mount, Andrew S., Shah, Nihar M.
• Granted Patent: US 9,560,848 B2
• Time in Patent Office: Days
• US Class Current: 424/78.09
• CPC Class Codes: A01N 33/10 having at least one oxygen or sulfur atom directly attached to an aromatic ring system

Abstract

A method of deterring biofouling of a surface comprising attaching an adduct having formula (I) or noradrenalin to the surface. Formula (I) being defined as compounds that have the formula A-L-R wherein A is i) a C6 or C10 substituted aryl ring, or ii) a C1-C9 substituted or unsubstituted heteroaryl ring: L is a linking group, and R is a primary amino moiety comprising unit.

Claims

1. A method of deterring biofouling of a surface comprising attaching an adduct having formula I to the surface.

2. The method of claim 1, wherein the adduct having formula I is covalently bonded to a monomer or a polymer, the monomer or polymer comprising a component selected from the group consisting of methacrylic acid and 2-hydroxyethyl methacrylate.

3. The method of claim 1, wherein the surface is a surface exposed to a marine environment.

5. The method of claim 1, wherein the method prevents biofouling by a mollusk, a crustacean, a Bryozoa, or a polychaet on the surface.

6. The method of claim 5, wherein the mollusk is selected from the group consisting of oysters.

8. The method of claim 5, wherein the crustacean is selected from the group consisting of barnacles.

22. The method of claim 1, wherein the adduct of Formula I is an agonist for a G-protein coupled receptor.

25. The method of claim 2, wherein the adduct having Formula I is covalently bonded to the surface by the monomer or the polymer.

29. The method of claim 22, wherein the agonist for a G-protein coupled receptor is noradrenaline.

4. (canceled)

7. (canceled)

9. (canceled)

10. A composition comprising an adduct having formula I linked to a polymer, said adduct being present in said composition in an amount effective to inhibit the attachment of biofouling organisms on a surface to which said composition is applied.

11. The composition of claim 10, wherein the polymer is methacrylic acid or 2-hydroxyethyl methacrylate.

14. A composition according to claim 10, wherein the adduct having formula I is present in an amount from about 30 μ

M to about 100 μ

M.

15. A composition according to claim 10, further comprising a film forming agent.

16. The composition according to claim 10, wherein the composition is a paint or a varnish.

17. The composition according to claim 16, wherein the composition is a marine paint.

24. The composition of claim 10 wherein the adduct of Formula I is an agonist for a G-protein coupled receptor.

30. The composition of claim 24, wherein the agonist for a G-protein coupled receptor is noradrenalin.

12. (canceled)

13. (canceled)

18. (canceled)

19. An anti-fouling surface comprising an effective amount of an adduct having Formula I, wherein the compound or a biologically active fragment thereof is releasable from the surface.

20. The anti-fouling surface of claim 19, wherein the release of the compound is a sustained release.

21. The anti-fouling surface of claim 19, wherein the release of the compound is at a constant rate.

23. (canceled)

26. (canceled)

27. (canceled)

28. (canceled)