METHOD FOR INTEGRATING LARGE SCALE BIOLOGICAL DATA WITH IMAGING
First Claim
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1. A method of predicting a patient outcome or endpoint from imaging studies comprising the steps of:
- (a) defining a set of M patients or samples of interest, some of which have associated imaging data;
(b) constructing an image feature matrix from said associated imaging data, wherein said image feature matrix comprises N image features;
(c) defining a set of at least one endpoint of interest;
(d) creating an association map between one or more of said N image features and said at least one endpoint of interest; and
(e) using said association map to analyze an imaging study to predict or characterize a patient outcome or endpoint.
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Abstract
Methods for extracting large scale biological, biochemical or molecular information about an index disease, biological state, or systems from imaging by correlating the imaging features associated with said disease, state or system with corresponding large scale biological data.
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Citations
20 Claims
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1. A method of predicting a patient outcome or endpoint from imaging studies comprising the steps of:
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(a) defining a set of M patients or samples of interest, some of which have associated imaging data; (b) constructing an image feature matrix from said associated imaging data, wherein said image feature matrix comprises N image features; (c) defining a set of at least one endpoint of interest; (d) creating an association map between one or more of said N image features and said at least one endpoint of interest; and (e) using said association map to analyze an imaging study to predict or characterize a patient outcome or endpoint. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification