MODEL ENHANCED IMAGING
First Claim
1. A therapy treatment response simulator, comprising:
- a modeler that generates a model of a structure of an object or subject to be treated based on information about the object or subject; and
a predictor that generates a predicted response indicative of how the structure is likely to respond to the treatment based on the model and a therapy treatment plan.
1 Assignment
0 Petitions
Accused Products
Abstract
A therapy treatment response simulator includes a modeler (202) that generates a model of a structure of an object or subject based on information about the object or subject and a predictor (204) that generates a prediction indicative of how the structure is likely to respond to treatment based on the model and a therapy treatment plan. In another aspect, a system includes performing a patient state determining in silico simulation for a patient using a candidate set of parameters corresponding to another patient and producing a first signal indicative of a predicted state of the patient, and generating a second signal indicative of whether the candidate set of parameters are suitable for the patient based on a known state of the patient.
56 Citations
87 Claims
-
1. A therapy treatment response simulator, comprising:
-
a modeler that generates a model of a structure of an object or subject to be treated based on information about the object or subject; and a predictor that generates a predicted response indicative of how the structure is likely to respond to the treatment based on the model and a therapy treatment plan. - View Dependent Claims (2, 3, 4, 6, 7, 8, 9, 10)
-
-
5. (canceled)
-
11. A therapy system, comprising:
-
a treatment response simulator that generates a parameter map that includes quantitative information indicative of how a first structure of an object or subject is likely to respond to treatment based on a model of the object or subject and a therapy treatment plan for the object or subject; and a treatment monitoring system that enhances image data generated from data acquired after the treatment based on the parameter map. - View Dependent Claims (13, 15, 16, 18)
-
-
12. (canceled)
-
14. (canceled)
-
17. (canceled)
-
19. A method, comprising:
-
generating a model indicative of a first structure of an object or subject based on image data indicative of the structure generated from data acquired prior to treatment; generating a prediction indicative of how the first structure is likely to respond to treatment based on the model and a therapy treatment plan; and generating a parameter map that includes quantitative information about tracer uptake by the first structure based on the prediction. - View Dependent Claims (20, 21, 22)
-
-
23. A method, comprising:
-
simulating a first response of a target tissue to a treatment; simulating a second response of a reference tissue to the treatment; treating the target tissue and the reference tissue; determining a third response of the target tissue to the treatment; determining a fourth response of the reference tissue to the treatment; and normalizing the third response based on the fourth response. - View Dependent Claims (24, 25, 26)
-
-
27. A method of determining therapy efficacy, comprising:
-
obtaining pre-treatment information; developing a model of a likely affect of a therapy based on the pre-treatment information; obtaining a post-treatment functional image data; and comparing the post-treatment functional image to the model to determine the therapy efficacy. - View Dependent Claims (28, 29, 30)
-
-
31-42. -42. (canceled)
-
43. A method, comprising:
-
selecting a set of parameters based on processed patient data for a first patient, wherein the set of parameters corresponds to a different patient; and performing a first in silico simulation based on the set of parameters, wherein simulation results predict a state of the first patient. - View Dependent Claims (44, 45, 46, 47, 48)
-
-
49. (canceled)
-
50. A system for identifying at least one candidate radiation treatment plan, comprising:
-
a data repository that includes radiation treatment plans for previously treated patients and related information about the previously treated patients; a treatment plan search engine that searches the data repository (906) for radiation treatment plans based on information about a patient to be treated and generates search results; and a candidate radiation treatment plan identifier that identifies at least one of radiation treatment plan in the search results based on a similarity between the information about the patient to be treated and corresponding information about the previously treated patient. - View Dependent Claims (51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61)
-
-
62-77. -77. (canceled)
-
78. A method, comprising:
- identifying a candidate treatment plan for treating a tumor in a first patient based on matching characteristics of the first patient with corresponding characteristics of a previously treated patient, wherein the candidate treatment plan is selected from a repository of validated treatment plans for previously treated patients.
- View Dependent Claims (79, 80, 81, 82, 83, 84, 85, 86, 87)
Specification