MICROFLUIDIC SYSTEM FOR DETECTING A BIOLOGICAL ENTITY IN A SAMPLE
First Claim
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1. A microfluidic system for detecting a biological entity in a sample volume, the microfluidic system comprising:
- a chamber configured to receive the sample volume, wherein the chamber comprises a detection region for detecting the biological entity;
a first port in fluid communication with the chamber; and
a second port comprising a filter in fluid communication with the chamber; and
wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber.
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Abstract
According to various embodiments, a microfluidic system for detecting a biological entity in a sample volume is provided. The microfluidic system may include: a chamber configured to receive the sample volume, wherein the chamber includes a detection region for detecting the biological entity; a first port in fluid communication with the chamber; and a second port including a filter in fluid communication with the chamber; and wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber.
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Citations
29 Claims
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1. A microfluidic system for detecting a biological entity in a sample volume, the microfluidic system comprising:
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a chamber configured to receive the sample volume, wherein the chamber comprises a detection region for detecting the biological entity; a first port in fluid communication with the chamber; and a second port comprising a filter in fluid communication with the chamber; and wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for manufacturing a microfluidic system for detecting a biological entity in a sample volume, the method comprising:
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providing a chamber configured to receive the sample volume, wherein the chamber comprises a detection region for detecting the biological entity; providing a first port in fluid communication with the chamber; and providing a second port comprising a filter in fluid communication with the chamber; and wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber.
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15. A method for detecting a biological entity in a sample volume using a microfluidic system for detecting a biological entity in a sample volume, the microfluidic system comprising:
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a chamber configured to receive the sample volume, wherein the chamber comprises a detection region for detecting the biological entity; a first port in fluid communication with the chamber; and a second port comprising a filter in fluid communication with the chamber; and wherein a fluid provided to the first port or the second port flows between the first port and the second port through the chamber; the method comprising; providing the sample volume to the chamber; providing the fluid to the first port to pass the sample volume through the filter to retain the biological entity; removing the biological entity from the filter to the detection region of the chamber; and detecting the biological entity. - View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
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Specification