Novel Ayurvedic Formulation Advocated for the Prevention and Management of Coronary Heart Disease

• US 20110135771A1
• Filed: 06/05/2009
• Published: 06/09/2011
• Est. Priority Date: 02/04/2009
• Status: Active Grant

• Current Assignee: Anurag Sharma
• Original Assignee: Anurag Sharma
• Inventors: Dubey, Govind Prasad, Rajamanickman, G. Victor
• Granted Patent: US 8,318,216 B2
• Time in Patent Office: Days
• US Class Current: 424/769
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/28 Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• CPC Class Codes: A61K 36/328 Commiphora, e.g. mecca myrrh or balm of Gilead
• CPC Class Codes: A61P 9/00 Drugs for disorders of the cardiovascular system

Abstract

A novel herbal formulation for the prevention and management of various CHD risk factors including vascular inflammatory process responsible for cardiovascular events comprising a hydro-alcoholic extraction of commiphora mukul, Terminalia arjuna, Inula recemosa and Hippophae rhamonoides with or without known additives.

Claims

1-6. -6. (canceled)

7. An herbal formulation for the prevention and management of various CHD risk factors comprising:

a hydro-alcoholic extraction of Commiphora mukul, Terminalia arjuna, Inula recemose and Hippophae rhamonoides.

8. The herbal formulation as claimed in claim 7, wherein said plants are present in the following doses:

9. The herbal formulation as claimed in claim 7, further comprising at least one additive.

10. The herbal formulation as claimed in claim 9, wherein said at least one additive comprises minerals, vitamin, salts filler and binders.

11. The herbal formulation as claimed in claim 7, wherein the CHD risk factor includes vascular inflammatory process responsible for cardio vascular events.

12. A process for preparation of novel formulation for the prevention and management of various CHD risk factors comprising:

preparing a hydro-alcoholic plant extract of Commiphora mukul, Terminalia arjuna, Inula recemosa and Hippophae rhamonoides by placing Commiphora mukul, Terminalia arjuna, and Inula recemosa in a solution of water and methanol at 70°

-80°

C. and maintaining the pH of the solution between 7-10;

separating chromotographically the Commiphora mukul, Terminalia arjuna, Inula recemosa and Hippophae rhamonoides by using TLC, HPLC and HPTLC; and

supporting molecular characterization of the plant extract by using IR and NMR.

13. The process as claimed in claim 12, wherein water and methanol are present in a ratio of 70:

30.

14. The process as claimed in claim 12, wherein said plants are present in the following doses: