TYPE II DIABETES MOLECULAR BIOPROFILE AND METHOD AND SYSTEM OF USING THE SAME
First Claim
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1. A method of using a Type II diabetes molecular bioprofile comprising the steps of:
- (a) analyzing a biological sample from a subject at risk for Type II diabetes, and(b) preparing a Type II diabetes molecular bioprofile of said subject, wherein said Type II diabetes molecular bioprofile comprises a weighted score for each analyte in a core group of analytes, wherein each weighted score is calculated from a measured concentration of the respective analyte in the biological sample and a respective weighting value.
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Abstract
Molecular bioprofiles comprising biologically correlated and relevant analytes that impact the biological state of a human health condition compared to a control population are provided. These molecular bioprofiles are useful in several ways including but not limited to, monitoring a disease or condition'"'"'s progression, evaluating the impact of an agent or compound on a disease or condition, evaluating the impact of a lifestyle change on a disease or condition and assessing the risk of the disease or condition to a subject. Type II diabetes molecular bioprofiles are of particular interest.
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Citations
23 Claims
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1. A method of using a Type II diabetes molecular bioprofile comprising the steps of:
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(a) analyzing a biological sample from a subject at risk for Type II diabetes, and (b) preparing a Type II diabetes molecular bioprofile of said subject, wherein said Type II diabetes molecular bioprofile comprises a weighted score for each analyte in a core group of analytes, wherein each weighted score is calculated from a measured concentration of the respective analyte in the biological sample and a respective weighting value. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of using a Type II diabetes molecular bioprofile comprising the steps of:
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(a) analyzing a biological sample from a subject at risk for Type II diabetes, and (b) preparing a Type II diabetes molecular bioprofile of said subject, wherein said Type II diabetes molecular bioprofile comprises a weighted score for each analyte in a core group of analytes, wherein the weighting value of each analyte in said core group of analytes is in a predetermined range. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18)
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19-20. -20. (canceled)
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21. A method of monitoring Type II diabetes in a subject at risk for Type II diabetes comprising the steps of:
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(a) analyzing a first biological sample from a subject at risk for Type II diabetes; (b) preparing a first Type II diabetes molecular bioprofile of said subject, wherein said first Type II diabetes molecular bioprofile comprises a first weighted score for each analyte in a core group of analytes, wherein each of said first weighted scores is derived from a measurement obtained from said first biological sample and a respective weighting value; (c) analyzing a second biological sample from said subject; (d) preparing a second Type II diabetes molecular bioprofile of said subject, wherein said second Type II diabetes molecular bioprofile comprises a second weighted score for each analyte in the core group of analytes, wherein each of said second weighted scores is derived from a measurement obtained from said second biological sample and the respective weighting value; and (e) monitoring Type II diabetes in said subject as function of said first and second Type II diabetes molecular bioprofiles. - View Dependent Claims (22)
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23-29. -29. (canceled)
Specification