METHOD FOR SUPPRESSING EXCESSIVE APPETITE

• US 20110136909A1
• Filed: 12/20/2010
• Published: 06/09/2011
• Est. Priority Date: 06/19/2008
• Status: Abandoned Application

• Current Assignee: Ajinomoto Co., Inc.
• Original Assignee: Ajinomoto Co., Inc.
• Inventors: Kimura, Eiichiro, Imada, Toshifumi, Torii, Kunio, Tanaka, Tatsuro, Tomoe, Miki, Hao, Shuzhen, Uneyama, Hisayuki
• Application Number:
  US12/972,670
• Publication Number:
  US 20110136909A1
• Time in Patent Office: Days
• US Class Current: 514/561
• CPC Class Codes: A23K 20/10 Organic substances
• CPC Class Codes: A23L 33/175 Amino acids
• CPC Class Codes: A23L 33/30 Dietetic or nutritional methods, e.g. for losing weight A23L33/10 takes precedence
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2200/30 Foods, ingredients or supplements having a functional effect on health
• CPC Class Codes: A61K 31/13 Amines A61K31/04 takes precedence
• CPC Class Codes: A61K 31/198 Alpha-amino acids, e.g. alanine or edetic acid [EDTA] betaine A61K31/205; proline A61K31/401; tryptophan A61K31/405; histidine A61K31/4172; peptides not degraded to individual amino acids A61K38/00
• CPC Class Codes: A61P 3/00 Drugs for disorders of the metabolism of the blood or the extracellular fluid A61P7/00
• CPC Class Codes: A61P 3/04 Anorexiants; Antiobesity agents

Abstract

Agents for the inhibition, suppression, or prevention of overeating include glutamic acid and/or at least one of its salts, as is or in a carrier or base, and have superior safety at a low price and further have a favorable flavor and are suited for long-term use. Such agents will amplify or sustain a sense of fullness and, further, are effective against appetite stimulation that arises regardless of a sense of fullness with respect to foods that are, for example, sweet or delicious, especially for a person who has a drive for thinness.

Claims

1. A method for suppressing overeating, said method comprising ingesting at least one substance selected from the group consisting of glutamic acid and a salt thereof, in an amount sufficient to suppress overeating, by a person who needs suppression of overeating.

2. The method according to claim 1, wherein said sufficient amount for suppressing overeating is between 0.01 g to 100 g as a free glutamic acid, per ingestion for an adult human.

3. The method according to claim 1, further comprising:

adding between 0.01 g to 100 g of said substance per ingestion to a food or drink;

wherein said ingesting comprises ingesting said food or drink.

4. The method according to claim 3, wherein said adding comprises adding said substance to a concentration of between 0.0001% to 10% by weight as a free glutamic acid in said food or drink.

5. The method according to claim 1, wherein said person is a person who has drive for thinness as indicated by their EDI Section A score.

6. The method according to claim 1, wherein said person has a non-zero EDI Section A score.

7. The method according to claim 1, further comprising identifying said person prior to said ingesting as a person who agrees with at least one statement having a meaning substantially the same as at least one of following statements:

(1) I eat sweets and carbohydrates without feeling nervous;

(2) I think about dieting;

(3) I feel extremely guilty after overeating;

(4) I am terrified of gaining weight;

(5) I exaggerate or magnify the importance of weight;

(6) I am preoccupied with the desire to be thinner; and

(7) If I gain a pound I get worried that I will keep gaining.

8. The method for controlling or improving obesity, the method comprising suppressing overeating according to the method of claim 1.

9. The method for suppressing overeating by a patient who overeats, the method comprising prescribing to the patient medical food comprising:

(A) at least one substance selected from the group consisting of glutamic acid and a salt thereof;

or

(B) a food or drink to which at least one substance selected from the group consisting of glutamic acid and a salt thereof has been added.

10. The method according to claim 9, wherein said medical food is:

(A) 0.01 g to 100 g of at least one substance selected from the group consisting of glutamic acid and a salt thereof, as a free glutamic acid, per ingestion by a adult human;

or

(B) a food or drink to which 0.01 g to 100 g of at least one substance selected from the group consisting of glutamic acid and a salt thereof has been added, as a free glutamic acid, per ingestion by an adult human.

11. The method according to claim 9, wherein said medical food comprises said substance in a concentration of 0.0001% to 10% by weight as a free glutamic acid.

12. The method according to claim 9, wherein said prescribing comprises prescribing said medical food to a person who has drive for thinness as indicated by their EDI Section A score.

13. The method according to claim 9, wherein said person has a non-zero EDI Section A score.

14. The method according to claim 9, further comprising identifying said patient prior to said prescribing as a person who agrees with at least one statement having a meaning substantially the same as at least one of the following statements:

(1) I eat sweets and carbohydrates without feeling nervous,

(2) I think about dieting,

(3) I feel extremely guilty after overeating,

(4) I am terrified of gaining weight,

(5) I exaggerate or magnify the importance of weight,

(6) I am preoccupied with the desire to be thinner, and

(7) If I gain a pound I get worried that I will keep gaining.

15. A method for controlling or improving obesity, said method comprising suppressing overeating according to the method of claim 9.