IMAGE PROCESSING APPARATUS AND IMAGE PROCESSING METHOD

• US 20110137157A1
• Filed: 11/08/2010
• Published: 06/09/2011
• Est. Priority Date: 12/08/2009
• Status: Abandoned Application

• Current Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Original Assignee: Canon Kabushiki Kaisha (Canon Inc.)
• Inventors: Nakano, Yuta, Satoh, Kiyohide, Iwase, Yoshihiko, Imamura, Hiroshi, Katayama, Akihiro
• Application Number:
  US12/941,351
• Publication Number:
  US 20110137157A1
• Time in Patent Office: Days
• US Class Current: 600/425
• CPC Class Codes: G06T 2207/10081 Computed x-ray tomography [CT]
• CPC Class Codes: G06T 2207/30041 Eye; Retina; Ophthalmic
• CPC Class Codes: G06T 7/0012 Biomedical image inspection

Abstract

This invention concerns the acquisition of diagnosis information data effective for diagnosing eye disease independently of the eye state. An image processing apparatus for processing a tomogram of an eye includes a unit configured to determine an eye feature based on the tomogram and thus determine the eye state, a unit configured to detect, from the tomogram, a detection target to be used to calculate diagnosis information data quantitatively representing the determined eye state, and a unit configured to calculate the diagnosis information data using position information of the detection target. In accordance with the eye state, the detection unit changes the detection target or an algorithm to be used to detect the detection target.

Claims

1. An image processing apparatus for processing a tomogram of an eye, comprising:

a determination unit configured to determine a state of a disease in the eye based on information of the tomogram; and

a detection unit configured to change, in accordance with the state of the disease in the eye determined by said determination unit, one of a detection target to be used to calculate diagnosis information data quantitatively representing the state of the disease and an algorithm to be used to detect the detection target.

2. The apparatus according to claim 1, wherein

the detection target includes a predetermined layer of the tomogram, and

if a shape of the predetermined layer has changed, or the tomogram includes a predetermined tissue, said detection unit changes a detection parameter to be used to detect the predetermined layer included in the detection target, and then redetects the predetermined layer.

3. The apparatus according to claim 2, wherein presence/absence of the change of the shape of the predetermined layer includes presence/absence of distortion of retinal pigment epithelium layer of the eye, and presence/absence of the predetermined tissue includes one of presence/absence of a white spot and presence/absence of a cyst.

4. The apparatus according to claim 3, wherein

said determination unit determines

a first state upon determining that the distortion of the retinal pigment epithelium layer of the eye does not exist, and neither the white spot nor the cyst exists,

a second state upon determining that the distortion of the retinal pigment epithelium layer of the eye exists, or not the cyst but the white spot exists, and

a third state upon determining the cyst exists, and

said detection unit detects

an inner limiting membrane, a nerve fiber layer boundary, and a retinal pigment epithelium layer boundary as the detection target when said determination unit has determined the first state,

the inner limiting membrane, the retinal pigment epithelium layer boundary, and a retinal pigment epithelium layer boundary assuming that the retinal pigment epithelium layer has no distortion as the detection target when said determination unit has determined the second state, and

the inner limiting membrane and the retinal pigment epithelium layer boundary as the detection target when said determination unit has determined the third state.

5. The apparatus according to claim 4, wherein

when said determination unit has determined that the distortion of the retinal pigment epithelium layer of the eye exists, said detection unit changes a detection parameter to be used to detect the retinal pigment epithelium layer boundary in a region with the distortion, and then redetects the retinal pigment epithelium layer boundary,

when said determination unit has determined that the white spot exists, said detection unit changes a detection parameter to be used to detect the retinal pigment epithelium layer boundary located at a deep position in a depth direction relative to the determined white spot, and then redetects the retinal pigment epithelium layer boundary.

6. The apparatus according to claim 4, further comprising a calculation unit configured to calculate

a nerve fiber layer thickness and a thickness of entire retina as the diagnosis information data when said determination unit has determined the first state,

the thickness of entire retina and an area or volume of a region between the retinal pigment epithelium layer boundary and the retinal pigment epithelium layer boundary assuming that the retinal pigment epithelium layer has no distortion as the diagnosis information data when said determination unit has determined the second state, and

the thickness of entire retina as the diagnosis information data when said determination unit has determined the third state.

7. The apparatus according to claim 4, further comprising a specifying unit configured to extract a depressed portion of the inner limiting membrane so as to extract an optic disc portion and a macular portion of the eye, and specify the optic disc portion and the macular portion based on presence/absence of blood vessels of retina and a nerve fiber layer thickness in the depressed portion,

wherein the tomogram of the eye undergoes processing for each part specified by said specifying unit.

8. The apparatus according to claim 6, further comprising:

an alignment unit configured to align a first tomogram whose diagnosis information data is calculated by said calculation unit with a second tomogram whose diagnosis information data is calculated by said calculation unit and whose imaging timing is different from that of the first tomogram; and

a difference calculation unit configured to calculate follow-up diagnosis information data representing a difference between the diagnosis information data of the first tomogram and that of the second tomogram by obtaining a difference in specified position information between the first tomogram and the second tomogram which are aligned by said alignment unit.

9. The apparatus according to claim 8, wherein said alignment unit

performs alignment based on, out of the detection target detected by said detection unit, a region selected as a reference in accordance with the state of the disease of the eye determined by said determination unit, and

performs alignment using a processing method selected in accordance with the state of the disease of the eye determined by said determination unit.

10. An image processing method of an image processing apparatus for processing a tomogram of an eye, comprising:

causing a determination unit to determine a state of a disease in the eye based on information of the tomogram; and

causing a detection unit to change, in accordance with the state of the disease in the eye determined by the determination unit, one of a detection target to be used to calculate diagnosis information data quantitatively representing the state of the disease and an algorithm to be used to detect the detection target.

11. A computer-readable storage medium storing a program that causes a computer to execute steps of an image processing method of claim 10.