SYSTEMS AND METHODS FOR DETECTING CARDIOVASCULAR DISEASE

• US 20110137210A1
• Filed: 12/08/2010
• Published: 06/09/2011
• Est. Priority Date: 12/08/2009
• Status: Abandoned Application

• Current Assignee: AUM Cardiovascular, Inc.
• Original Assignee: AUM Cardiovascular, Inc.
• Inventors: Johnson, Marie A.
• Application Number:
  US12/962,812
• Publication Number:
  US 20110137210A1
• Time in Patent Office: Days
• US Class Current: 600/586
• CPC Class Codes: A61B 2562/0204 Acoustic sensors
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/02028 Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/03 Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs A61B5/205 takes precedence
• CPC Class Codes: A61B 5/4833 Assessment of subject's compliance to treatment
• CPC Class Codes: A61B 5/6806 Gloves
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61B 5/6823 Trunk, e.g., chest, back, abdomen, hip
• CPC Class Codes: A61B 5/6824 Arm or wrist
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6831 Straps, bands or harnesses
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6898 Portable consumer electronic devices, e.g. music players, telephones, tablet computers
• CPC Class Codes: A61B 5/7282 Event detection, e.g. detecting unique waveforms indicative of a medical condition A61B5/4094, A61B5/4818, A61B5/349, A61B5/0823 take precedence
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/7425 Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image geometric transforms for image registration G06T3/14; enhancement using image fusion G06T5/50; algorithms for registration of images G06T7/30
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: A61B 5/7475 : User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: A61B 7/04 : Electric stethoscopes microphones, acoustic transducers therefor H04R
• CPC Class Codes: A61B 7/045 : Detection of Korotkoff sounds A61B5/0225 takes precedence; measuring blood pressure A61B5/021

Abstract

Embodiments of the invention provide such an improved system and method. In particular, embodiments relate to systems, methods and apparatuses which use acoustic data in the detection of coronary artery disease. Embodiments can enable fast, non-invasive identification of clinically relevant coronary artery disease, which can ultimately save lives. The non-invasive nature is one example of a multitude of convenient aspects of embodiments that can be used to meet a large, as yet unmet need in a cost-effective and accurate manner. Results can be provided in real-time and with clarity, providing quick and easily understandable indications that can shorten the path to intervention for patients, making embodiments suitable for a wide range of environments, purposes, users and patients.

Claims

1. A system for use in the detection of coronary artery disease comprising:

at least one acoustic sensor;

a housing coupled to the at least one acoustic sensor and configured to position the at least one acoustic sensor to collect acoustic data;

an electronic subsystem configured to condition acoustic data received from the at least one acoustic sensor;

a processor coupled to the electronic subsystem and configured to receive the conditioned acoustic data and determine a presence of coronary artery disease based at least in part on a shape of a waveform of the conditioned acoustic data; and

an electronic device configured to present a graphical user interface that includes at least one waveform associated with the conditioned acoustic data.

2. The system of claim 1, wherein the graphical user interface includes two waveforms, a first waveform associated with a first set of acoustic data for a patient and a second waveform associated with a second set of acoustic data for the patient.

3. The system of claim 2, wherein the first waveform indicates a presence of coronary artery disease and the second waveform is associated with acoustic data taken after a treatment of the coronary artery disease.

4. The system of claim 1, wherein at least one of the processor and the electronic subsystem is coupled to the housing.

5. The system of claim 1, wherein the electronic device comprises at least one of the processor and the electronic subsystem.

6. The system of claim 1, wherein the electronic device comprises one selected from the group consisting of:

a smart phone, a personal digital assistant, a tablet computer, an MP3 player, a laptop computer;

a notebook computer;

a desktop computer;

a monitor; and

a medical device.

7. The system of claim 1, wherein the housing comprises a hand-held device.

8. The system of claim 7, wherein the housing is coupled to the electronic device.

9. The system of claim 8, wherein the housing is wirelessly coupled to the electronic device.

10. The system of claim 1, wherein the housing comprises a patch.

11. The system of claim 1, wherein the housing comprises one of a glove or a body wrap.

12. The system of claim 1, wherein the graphical user interface includes a graphical depiction of a source of the acoustic data.

13. The system of claim 1, wherein the source of the acoustic data is a blood vessel.

14. The system of claim 1, wherein the graphical user interface includes a diagnostic conclusion.

15. A system for use in the detection of coronary artery disease comprising:

an acoustic system comprising;

at least one acoustic sensor,

a housing coupled to the at least one acoustic sensor and configured to position the at least one acoustic sensor to collect acoustic data,

an electronic subsystem configured to condition acoustic data received from the at least one acoustic sensor, and

a processor coupled to the electronic subsystem and configured to receive the conditioned acoustic data and determine a presence of coronary artery disease based at least in part on a shape of a waveform of the conditioned acoustic data; and

an electrocardiography device coupled to the acoustic system and configured to determine a presence of coronary artery disease based at least in part on an electrical signal.

16. The system of claim 15, further comprising a display device configured to present an indication of a presence or absence of coronary artery disease based at least in part on the shape of the waveform from the acoustic system and the electrical signal from the electrocardiography device.

17. A method of detecting coronary artery disease comprising:

receiving acoustic data;

conditioning the acoustic data;

plotting a waveform of the acoustic data;

analyzing the waveform for a waveform shape associated with coronary artery disease; and

presenting an output including the waveform.

18. The method of claim 17, further comprising collecting acoustic data.

19. The method of claim 17, wherein presenting further comprises presenting an output include a graphical depiction of a source of the acoustic data.

20. The method of claim 19, wherein presenting further comprises presenting an image of a blood vessel.

21. The method of claim 17, further comprising generating a diagnostic conclusion.

22. The method of claim 21, wherein if the diagnostic conclusion is a presence of coronary artery disease, the method further comprises:

recommending a treatment to a patient if the waveform shape is associated with coronary artery disease;

repeating the receiving, conditioning, plotting and analyzing for the patient after the treatment to obtain a second waveform; and

presenting an output including the waveform and the second waveform.

23. The method of claim 21, wherein the diagnostic conclusion comprises at least one of a prediction, a suggested test or a suggested treatment.

24. A system for use in the detection of coronary artery disease comprising:

at least one acoustic sensor;

a housing coupled to the at least one acoustic sensor and configured to position the at least one acoustic sensor to collect acoustic data;

an electronic subsystem configured to condition acoustic data received from the at least one acoustic sensor;

a processor coupled to the electronic subsystem and configured to receive the conditioned acoustic data and determine a presence of coronary artery disease based at least in part on a shape of a waveform of the conditioned acoustic data; and

an electronic display device configured to present an output related to whether a presence of coronary artery disease was determined, the output including a graphical depiction of a source of the acoustic data.

25. The system of claim 24, wherein the output includes at least one of a prediction, a suggested test or a suggested treatment.

26. The system of claim 24, wherein the source of the acoustic data is a blood vessel.

27. The system of claim 24, wherein the electronic device comprises one selected from the group consisting of:

a smart phone, a personal digital assistant, a tablet computer, an MP3 player, a laptop computer;

a notebook computer;

a desktop computer;

a monitor; and

a medical device.

28. The system of claim 24, wherein the housing comprises a hand-held device.

29. The system of claim 24, wherein the housing comprises a patch.

30. The system of claim 24, wherein the housing comprises one of a glove or a body wrap.