MULTI-CARTRIDGE FLUID DELIVERY DEVICE

• US 20110137287A1
• Filed: 01/25/2011
• Published: 06/09/2011
• Est. Priority Date: 03/30/2006
• Status: Active Grant

• Current Assignee: Mannkind Corporation
• Original Assignee: Valeritas, Inc. (Zealand Pharma A/S)
• Inventors: LEVESQUE, Steven F., NARDI, Ronald V., GONNELLI, Robert
• Granted Patent: US 8,361,053 B2
• Time in Patent Office: Days
• US Class Current: 604/506
• CPC Class Codes: A61M 5/1407 Infusion of two or more substances
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure
• CPC Class Codes: A61M 5/1454 spring-actuated, e.g. by a clockwork
• CPC Class Codes: A61M 5/16827 controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/32 Needles; Details of needles pertaining to their connection with syringe or hub infusion needles A61M5/158; Accessories for bringing the needle into, or holding the needle on, the body A61M5/42, A61M5/46 take precedence; guide needles for catheters A61M25/065; Devices for protection of needles apparatus specially adapted for cleaning or sterilising needles A61M5/001
• CPC Class Codes: A61M 5/3298 Needles arranged in parallel
• CPC Class Codes: A61P 3/10 for hyperglycaemia, e.g. antidiabetics

Abstract

A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.

Claims

1. A fluid delivery device for administering a first medicament and a second medicament comprising:

a housing,

a first reservoir within the housing and configured to contain the first medicament,

a second reservoir within the housing and configured to contain the second medicament, and

a needle having a first end configured for fluid communication with the first reservoir and a second end configured to extend exteriorly from the housing.

2. The fluid delivery device of claim 1, further comprising a basal drive mechanism for providing a basal delivery of the first medicament.

3. The fluid delivery device of claim 2, wherein the basal drive mechanism provides a basal delivery of the second medicament.

4. The fluid delivery device of claim 2, wherein the basal drive mechanism is a first basal drive mechanism and further comprising a second basal drive mechanism for providing a basal delivery of the second medicament.

5. The fluid delivery device of claim 4, wherein the first and second basal drive mechanisms each include a coil spring, a basal drive piston, and a hydraulic fluid reservoir.

6. The fluid delivery device of claim 5, further comprising a first pump chamber in fluid communication with the hydraulic fluid reservoir of the first basal drive mechanism via a first flow restrictor and a second pump chamber in fluid communication with the hydraulic fluid reservoir of the second basal drive mechanism via a second flow restrictor.

7. The fluid delivery device of claim 6, further comprising a first delivery piston positioned within the first fluid reservoir to exert a force on the first medicament within the first fluid reservoir and a second delivery piston positioned within the second fluid reservoir to exert a force on the second medicament within the second fluid reservoir.

8. The fluid delivery device of claim 3, further comprising a bolus drive mechanism for providing a bolus delivery of the first medicament.

9. The fluid delivery device of claim 8, wherein the bolus drive mechanism provides a bolus delivery of the second medicament.

10. The fluid delivery device of claim 8, wherein the bolus drive mechanism is a first bolus drive mechanism and wherein the fluid delivery device further comprises a second bolus drive mechanism for providing a bolus delivery of the second medicament.

11. The fluid delivery device of claim 8, wherein the bolus drive mechanism includes a ratchet and a bolus piston coupled to the ratchet.

12. The fluid delivery device of claim 11, further comprising a pump chamber associated with the first fluid reservoir and wherein the bolus piston is positioned within a bolus fluid reservoir in fluid communication with the pump chamber.

13-32. -32. (canceled)

33. A method of administering first and second medicaments from an fluid delivery device comprising:

delivering a first basal delivery of the first medicament, and

delivering a second basal delivery of the second medicament.

36. The method of claim 33, wherein delivering the first basal delivery includes actuating a first basal drive mechanism and delivering the second basal delivery includes actuating the first basal drive mechanism.

37. The method of claim 33, wherein delivering the first basal delivery includes actuating a first basal drive mechanism and delivering the second basal delivery includes actuating a second basal drive mechanism.

38. The method of claim 33, further including delivering a first bolus delivery of the first medicament and delivering a second bolus delivery of the second medicament.

41. The method of claim 38, wherein delivering the first bolus delivery includes actuating a first bolus drive mechanism and delivering the second bolus delivery includes actuating the first bolus drive mechanism.

34-35. -35. (canceled)

39-40. -40. (canceled)

42-43. -43. (canceled)

44. A method of administering first and second medicaments from a fluid delivery device comprising:

(i) forcing hydraulic fluid from a hydraulic fluid reservoir into a first pump chamber to exert a force on a first movable barrier,

(ii) forcing hydraulic fluid from the hydraulic fluid reservoir into a second pump chamber to exert a force on a second movable barrier,

(iii) exerting a force on a first piston to expel at least a portion of the first medicament through an aperture of the first fluid reservoir, and

(iv) exerting a force on a second piston to expel at least a portion of the second medicament through an aperture of the second fluid reservoir.

45. The method of claim 44, wherein forcing hydraulic fluid from the hydraulic fluid reservoir includes applying a spring force to a piston within the hydraulic fluid reservoir.

46. The method of claim 44, wherein forcing the hydraulic fluid from the hydraulic fluid reservoir includes forcing hydraulic fluid from the hydraulic fluid reservoir through a flow restrictor and into the first and second pump chambers.