ULTRASOUND ABLATION APPARATUS WITH DISCRETE STAGGERED ABLATION ZONES

• US 20110137298A1
• Filed: 02/02/2011
• Published: 06/09/2011
• Est. Priority Date: 10/11/2001
• Status: Active Grant

• Current Assignee: St Jude Medical Incorporated (Abbott Laboratories)
• Original Assignee: St Jude Medical Incorporated (Abbott Laboratories)
• Inventors: NGUYEN, Tho Hoang, CHEN, Peter C., TRAN, Vivian, HATA, Cary, DE LA RAMA, Alan
• Granted Patent: US 8,974,446 B2
• Time in Patent Office: Days
• US Class Current: 606/1
• CPC Class Codes: A61B 17/2202 the ultrasound transducer being inside patient's body at the distal end of the catheter
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/00247 Making holes in the wall of the heart, e.g. laser Myocardial revascularization
• CPC Class Codes: A61B 2017/22021 electric leads passing through the catheter
• CPC Class Codes: A61B 2017/320084 Irrigation sleeves
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61N 2007/003 Destruction of nerve tissue
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/022 intracavitary

Abstract

An ablation apparatus comprises an ultrasonic transducer which includes a piezoelectric element having a cylindrical shape; a plurality of external electrodes disposed on the outer surface of the piezoelectric element; and at least one internal electrode disposed on the inner surface of the piezoelectric element. The at least one internal electrode provides corresponding internal electrode portions that are disposed opposite the external electrodes with respect to the piezoelectric element, the external electrodes and the at least one internal electrode to be energized to apply an electric field across the piezoelectric element. The ultrasonic ablation zones of the external electrodes are distributed in a staggered configuration so as to span one or more open arc segments around the longitudinal axis, and the ultrasound ablation zones of all external electrodes projected longitudinally onto any lateral plane which is perpendicular to the longitudinal axis span a substantially closed loop around the longitudinal axis.

Claims

1. An ablation apparatus comprising an ultrasonic transducer which includes:

a piezoelectric element having a cylindrical shape with a longitudinal axis, an inner surface facing inwardly toward the longitudinal axis, and an outer surface facing outwardly away from the longitudinal axis;

a plurality of external electrodes disposed on the outer surface of the piezoelectric element; and

at least one internal electrode disposed on the inner surface of the piezoelectric element;

wherein the at least one internal electrode provides corresponding internal electrode portions that are disposed opposite the plurality of external electrodes with respect to the piezoelectric element, the external electrodes and the at least one internal electrode to be energized to apply an electric field across the piezoelectric element between the external electrodes and the corresponding internal electrode portions, so as to produce ultrasonic ablation zones extending from the energized external electrodes outwardly away from the longitudinal axis; and

wherein the ultrasonic ablation zones of the external electrodes are distributed in a staggered configuration so as to span one or more open arc segments around the longitudinal axis, and the ultrasound ablation zones of all the external electrodes projected longitudinally onto any lateral plane which is perpendicular to the longitudinal axis span a substantially closed loop around the longitudinal axis.

2. The ablation apparatus of claim 1,

wherein the external electrodes are discretely spaced from each other at least one of longitudinally or laterally, and at least two of the external electrodes are spaced from one another longitudinally.

3. The ablation apparatus of claim 1,

wherein the external electrodes span one or more open arc segments around the longitudinal axis, and all the external electrodes projected longitudinally onto any lateral plane which is perpendicular to the longitudinal axis span a substantially closed loop around the longitudinal axis.

4. The ablation apparatus of claim 1,

wherein the external electrodes and the at least one internal electrode are independently controlled to be energized in one of simultaneous manner, sequential manner, and arbitrary manner to produce the ultrasonic ablation zones.

5. The ablation apparatus of claim 1,

wherein the external electrodes and the at least one internal electrode are energized by radiofrequency (RF) energy.

6. The ablation apparatus of claim 1, further comprising:

a body having a fluid cavity in which the ultrasonic transducer is disposed, the fluid cavity containing a fluid for transmitting ultrasonic energy.

7. The ablation apparatus of claim 6,

wherein the fluid cavity has a fluid inlet for fluid flow into the fluid cavity and a fluid outlet for fluid flow out of the fluid cavity.

8. The ablation apparatus of claim 1, further comprising:

a handle assembly;

a shaft having a main lumen, a proximal end coupled to the handle assembly, and a distal end;

a distal tip section coupled to the distal end of the shaft, the distal tip section having a non-compliant and non-porous cap that has a tubular wall that defines a bore; and

an irrigation tube extending through the main lumen and having a distal end that terminates in the bore, the irrigation tube to supply irrigation fluid to the bore;

wherein the ultrasonic transducer is housed inside the bore and spaced apart from the wall of the cap.

9. The ablation apparatus of claim 8, further comprising:

a plurality of thermocouple wires that are connected to the cap.

10. The ablation apparatus of claim 8, further comprising:

a plurality of ring electrodes provided in a spaced-apart manner about the outer surface of the shaft adjacent the distal tip section.

11. The ablation apparatus of claim 8, further comprising:

an inner sleeve secured in the main lumen at the distal end of the shaft.

12. The ablation apparatus of claim 8, further comprising:

an inner supporting member that extends through the main lumen of the shaft and the bore of the cap.

13. The ablation apparatus of claim 1, further comprising:

a handle assembly;

a shaft having a main lumen, a proximal end coupled to the handle assembly, and a distal end;

an inner sleeve secured in the main lumen;

a distal tip section coupled to the distal end of the shaft, the distal tip section having a non-compliant and non-porous cap that has a tubular wall that defines a bore;

an inner supporting member that extends through the main lumen of the shaft and the bore of the cap; and

an outer supporting member that extends through the inner sleeve and into the bore, with the inner supporting member housed in the outer supporting member;

wherein the ultrasonic transducer is housed inside the bore and spaced apart from the wall of the cap.

14. The ablation apparatus of claim 13,

wherein the inner supporting member is selected from the group consisting of a coil, a flat wire, and made of a material selected from the group consisting of a metal, an alloy, and a polymer.

15. The ablation apparatus of claim 1, further comprising:

an expandable member providing a fluid cavity in which the ultrasonic transducer is disposed.

16. The ablation apparatus of claim 15, further comprising:

a handle assembly;

a shaft having a proximal end coupled to the handle assembly, and a distal end, the shaft extending along an axis; and

a distal ring provided at the distal end and oriented perpendicular to the axis of the shaft, the distal ring having a plurality of electrodes positioned in spaced-apart manner about the distal ring;

wherein the ultrasonic transducer is positioned spaced apart from the distal ring; and

wherein the distal ring has a diameter that is greater than the fully expanded diameter of the expandable member.

17. The ablation apparatus of claim 16, further comprising:

an energy source coupled to the ultrasonic transducer; and

means coupled to the plurality of electrodes for processing electrical signals received from the plurality of electrodes.

18. An ablation apparatus comprising a body have an axis and an ultrasonic transducer connected to the body, the ultrasonic transducer including:

a piezoelectric element coupled to the body, the piezoelectric element having a hollow interior, an inner surface facing the hollow interior, and an outer surface facing outwardly away from the hollow interior;

a plurality of external electrodes disposed on the outer surface of the piezoelectric element; and

at least one internal electrode disposed on the inner surface of the piezoelectric element;

wherein the at least one internal electrode provides corresponding internal electrode portions that correspond to the plurality of external electrodes, the external electrodes and the at least one internal electrode to be energized to apply an electric field across the piezoelectric element between the external electrodes and the corresponding internal electrode portions, so as to produce ultrasonic ablation zones extending from the energized external electrodes outwardly away from the hollow interior; and

wherein the ultrasonic ablation zones of the external electrodes are distributed in a staggered configuration so as to span one or more open arc segments around the axis of the body, and the ultrasound ablation zones of all the external electrodes projected longitudinally onto any lateral plane which is perpendicular to the axis of the body span a substantially closed loop around the axis of the body.

19. The ablation apparatus of claim 18,

wherein the external electrodes span one or more open arc segments around the axis of the body, and all the external electrodes projected longitudinally onto any lateral plane which is perpendicular to the axis of the body span a substantially closed loop around the axis of the body.

20. The ablation apparatus of claim 18,

wherein the body has a fluid cavity in which the ultrasonic transducer is disposed, the fluid cavity containing a fluid for transmitting ultrasonic energy.