Compositions, Methods, and Kits for Eliciting an Immune Response
First Claim
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1. A conjugate comprising at least one antigen or small molecule conjugated to at least one polypeptide capable of binding a double-stranded polynucleotide, wherein the conjugate is able to elicit an immune response against the antigen or small molecule.
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Abstract
The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one antigen, in particular for enhancing antigen immunogenicity.
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Citations
25 Claims
- 1. A conjugate comprising at least one antigen or small molecule conjugated to at least one polypeptide capable of binding a double-stranded polynucleotide, wherein the conjugate is able to elicit an immune response against the antigen or small molecule.
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11. The conjugate of claim 11 wherein the polypeptide comprises E3L.
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22. A kit comprising
a) a polypeptide capable of binding a double-stranded polynucleotide; -
b) a dsRNA labeled with a first ligand; and c) a second ligand that is able to bind to the first ligand. - View Dependent Claims (23, 24, 25)
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Specification