SYSTEMS AND METHODS FOR PERFORMING PERITONEAL DIALYSIS

• US 20110144570A1
• Filed: 02/23/2011
• Published: 06/16/2011
• Est. Priority Date: 07/19/2002
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Pan, Lee, Childers, Robert W., Lauman, Brian
• Granted Patent: US 8,992,462 B2
• Time in Patent Office: Days
• US Class Current: 604/29
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/1696 with dialysate regeneration
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]

Abstract

Systems and methods for providing multiple pass continuous flow dialysis therapy are provided. The present invention includes a fluid circuit connected to a patient via a catheter thereby defining a fluid loop along which a therapy fluid including a dialysate can be continuously circulated into, through and out of a peritoneal cavity of a patient to remove a therapeutically effective amount of excess water and solutes including uremic toxins. The feed rate and discharge rate of therapy fluid into the fluid loop can be controllably regulated in proportion to the circulation rate of fluid in the fluid loop such that the therapy fluid can pass a multiple number of times along the fluid loop prior to discharge.

Claims

1. A system for providing peritoneal dialysis to a patient, the system comprising:

a catheter having an inflow lumen and an outflow lumen for communication with the patient'"'"'s peritoneal cavity;

a fluid circuit in fluid communication with the catheter capable of circulating a therapy fluid into, through and out of a peritoneal cavity of the patient;

a supply of a dialysate;

a chamber coupled fluidly to the dialysate supply and the fluid circuit through which the dialysate can be fed at a feed rate into the fluid circuit;

a cycler that pumps the dialysate into the fluid circuit and circulates the dialysate along the fluid circuit at a circulation rate to remove a therapeutic effective amount of solutes and excess water from the patient; and

a discharge fluid path fluidly coupled to the fluid circuit through which the therapy fluid is drained from the fluid circuit at a discharge rate effective to cause the therapy fluid to be circulated a plurality of times along the fluid circuit prior to discharge.

2. The system of claim 1, wherein the supply of dialysate includes about six liters or less of dialysate.

3. The system of claim 1, wherein the circulation rate is about 300 ml/min or less.

4. The system of claim 1, wherein the chamber is capable of and positioned to mix and heat the dialysate.

5. The system of claim 1, wherein the cycler includes a pump located downstream of the chamber and upstream of the fluid circuit.

6. The system of claim 1, wherein the feed rate and the discharge rate are maintained at an approximately equal rate that is less than the circulation rate.

7. The system of claim 1, which includes a pump and valve circuit located between the chamber and the fluid circuit.

8. The system of claim 1, wherein the dialysate is circulated along the fluid circuit a number of times that is approximately equal to the feed rate divided by a difference between the circulation rate and the discharge rate.

9. The system of claim 1 wherein the cycler includes a first pump and a second pump that cooperate to cause the therapy fluid to be circulated a plurality of times along the fluid circuit.

10. The system of claim 9, wherein the first pump and the second pump communicated fluidly via a plurality of parallel fluid lines.

11. The system of claim 9, which includes a plurality of valves operable with the first and second pumps to cause the therapy fluid to be circulated a plurality of times along the fluid circuit.

12. A system for providing peritoneal dialysis comprising:

a catheter in communication with the peritoneal cavity of the patient;

a circulation circuit in fluid communication with the catheter and capable of circulating a therapy fluid into, through and out of the patient'"'"'s peritoneal cavity;

a first pumping chamber in fluid communication with the circulation circuit;

a second pumping chamber in fluid communication with the circulation circuit;

a supply of therapy fluid in fluid communication with at least one of the first and second pumping chambers via a supply line;

a drain line in fluid communication with at least one of the first and second pumping chambers; and

a cycler including a first cycler pump operating with the first pump chamber, a second cycler pump operating with the second pump chamber and a plurality of valves for opening and closing the supply an drain lines, and wherein the cycler is configured and arranged to operate the first and second cycler pumps and the plurality of valves so as to cause the therapy fluid to be circulated a plurality of times along the circulation circuit prior to exiting the circulation circuit via the drain line.

13. The system of claim 12, wherein the catheter is a dual lumen catheter.

14. The system of claim 12, wherein the plurality of valves are upstream and downstream valves for at least one of the first and second pump chambers.

15. The system of claim 14, wherein the upstream and downstream valves can be toggled so that one of the first and second pumped chambers is caused to alternate between sending therapy fluid from the circulation circuit (i) to exit via the drain line and (ii) back to the circulation circuit.

16. The system of claim 15, wherein (i) and (ii) can occur while the other of the first and second pump chambers is caused to send therapy fluid from the supply to the circulation circuit.

17. The system of claim 15, wherein (ii) is facilitated via a fluid line extending from the drain line to the supply line.

18. The system of claim 15, wherein (ii) is facilitated via a fluid line in communication with the drain line and an inflow line of the circulation circuit.

19. The system of claim 12, wherein at least a portion of the therapy fluid exiting via the drain line is cleaned for reuse.

20. The system of claim 12, which includes a chamber located between the therapy fluid supply and the circulation circuit, the chamber used for at least one of heating and mixing the therapy fluid.

21. A system for providing peritoneal dialysis comprising:

a catheter in communication with the peritoneal cavity of the patient;

a circulation circuit in fluid communication with the catheter and capable of circulating a therapy fluid into, through and out of the patient'"'"'s peritoneal cavity;

a first pumping chamber in fluid communication with the circulation circuit;

a second pumping chamber in fluid communication with the circulation circuit;

a supply of therapy fluid in fluid communication with at least one of the first and second pumping chambers via a supply line;

a drain line in fluid communication with at least one of the first and second pumping chambers;

a bypass line located outside of the circulation circuit and communicating fluidly with the supply line and the drain line; and

a cycler including a first cycler pump operating with the first pump chamber and a second cycler pump operating with the second pump chamber, the cycler operating the first and second pump chambers and using the bypass line so as to cause the therapy fluid to be circulated a plurality of times along the circulation circuit prior to exiting the circulation circuit via the drain line.