METHOD AND DEVICE FOR MICRO-DOSING A LIQUID

• US 20110144615A1
• Filed: 06/18/2010
• Published: 06/16/2011
• Est. Priority Date: 12/18/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Haenggi, Roger, Niklaus, Hanspeter
• Granted Patent: US 8,419,691 B2
• Time in Patent Office: Days
• US Class Current: 604/500
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: B65D 83/0005 Containers or packages provided with a piston or with a movable bottom or partition having approximately the same section as the container B65D83/0072 takes precedence

Abstract

Methods and devices for micro-dosing a liquid are disclosed herein. According to one embodiment, a method for a time controlled micro-dosing of a liquid from a liquid reservoir includes: receiving the liquid reservoir with a structure wherein the structure is portable; securing the liquid reservoir to the structure; connecting a second end of a drive unit to a piston disposed within the liquid reservoir; activating a drive motor; displacing the drive unit with respect to the structure towards the piston in an axial direction with the drive motor; moving the piston axially within the liquid reservoir; and micro-dosing the liquid from the liquid reservoir.

Claims

1. A method for a time controlled micro-dosing of a liquid from a liquid reservoir, the method comprising:

receiving the liquid reservoir with a structure wherein the structure is portable;

securing the liquid reservoir to the structure;

providing a drive unit with a first end and a second end, and having a drive motor;

connecting the second end of the drive unit to a displacement piston disposed within the liquid reservoir;

activating the drive motor;

displacing the drive unit and drive motor with respect to the structure towards the displacement piston in an axial direction;

moving the displacement piston axially within the liquid reservoir; and

micro-dosing the liquid from the liquid reservoir, wherein

displacement in the axial direction of the drive unit and drive motor is effected by rotating with the drive unit a rotatable member coupled to the first end of the drive unit, the rotatable member having an outer thread which engage an inner thread disposed on a sleeve coupled to the structure, and

arranged between the drive unit and the second member is an anti-rotation element preventing rotation of the drive unit relative to the sleeve and permitting axial displacement of the drive unit relative to the sleeve.

2. The method of claim 1 wherein the drive unit is displaced from a retracted position to an extended position, and when the drive unit is in the extended position the second end of the drive unit is farthest away from the inner thread.

3. The method of claim 1 wherein the drive unit is displaced from a retracted position to an extended position, and when the drive unit is in the retracted position the inner thread at least partially circumferentially surrounds at least the first end of the drive unit.

4. The method of claim 1 further comprising supplying power to the drive motor via the anti-rotation element.

5. The method of claim 1 further comprising monitoring the drive unit with an encoder.

6. The method of claim 1 further comprising monitoring a force exerted on the displacement piston with a force sensor.

7. The method of claim 1 wherein a displacement of the drive motor is activated by a computerized control unit according to a specific activity profile for the micro-dosing of the liquid from the liquid reservoir.

8. The method of claim 1 wherein the liquid is insulin or a liquid pain killer.

9. A micro-dosing device for micro-dosing a liquid from a liquid reservoir, the micro-dosing device comprising:

a structure;

the liquid reservoir received within the structure and comprising a displacement piston;

a drive unit comprising a first end, a second end, and a drive motor;

a coupling member disposed at the second end of the drive unit and removably coupled to the displacement piston, wherein the displacement piston moves axially and dispenses the liquid from the liquid reservoir when the drive motor activates and axially displaces the drive unit relative to the structure;

a rotatable member coupled to the first end of the drive unit and comprising an outer thread coaxially arranged around an axis of rotation;

a sleeve comprising an inner thread that engages the outer thread of the rotatable member, wherein

the sleeve is integral with the structure or secured to the structure,

the drive motor rotates the rotatable member around an axis of rotation X to axially displace the rotatable member and the drive unit with respect to the sleeve; and

an anti-rotation element disposed between the drive unit and the sleeve wherein the anti-rotation element prevents a rotation of the drive unit relative to the sleeve and permits an axial displacement of the drive unit relative to the sleeve.

10. The micro-dosing device according to claim 9 wherein the rotatable member and the drive unit are axially displaced from a retracted position to an extended position, and when the drive unit is in the retracted position the inner thread at least partially circumferentially surrounds at least the first end of the drive unit.

11. The micro-dosing device of claim 10 wherein more than half of a length of the drive unit is at least partially circumferentially surrounded by the inner thread when the drive unit is in the retracted position.

12. The micro-dosing device of claim 10 wherein the sleeve is coupled to the structure, the inner thread is disposed on an inside of the sleeve, and the second end of the drive unit protrudes from the sleeve.

13. The micro-dosing device of claim 12 further comprising a sealing member disposed between the sleeve and the second end of the drive unit.

14. The micro-dosing device of claim 9 wherein the drive unit further comprises a gear disposed at the first end of the drive unit between the drive motor and the rotatable member.

15. The micro-dosing device of claim 9 wherein the drive motor rotates about a driving axis of rotation Y that is coaxially aligned with the axis of rotation X.

16. The micro-dosing device of claim 9 wherein the drive motor is supplied power via the anti-rotation element.

17. The micro-dosing device of claim 9 wherein the axis of rotation X is coaxially aligned with a central axis Z of the displacement piston.

18. The micro-dosing device of claim 9 wherein the drive unit further comprises an encoder that monitors an activity of the drive unit.

19. The micro-dosing device of claim 18 wherein the encoder is disposed at the second end of the drive unit, and is at least partially disposed within the displacement piston.

20. The micro-dosing device of claim 9 further comprising a force sensor that determines a force exerted on the displacement piston.

21. The micro-dosing device of claim 9 further comprising a computerized control unit that controls the axial displacement of the drive unit.