POLYMERIC STENT HAVING MODIFIED MOLECULAR STRUCTURES
First Claim
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1. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
- a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being greater than the second amount of alignment; and
a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops.
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Abstract
A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. By preferential mechanical deformation of the polymer, the polymer chains may be oriented to achieve certain desirable performance characteristics.
15 Citations
170 Claims
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1. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being greater than the second amount of alignment; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27)
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28. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being less than the second amount of alignment; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops. - View Dependent Claims (29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54)
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55. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being substantially equal to the second amount of alignment; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops. - View Dependent Claims (56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81)
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- 82. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being greater than the second amount of alignment, the plurality of hoops being interconnected to form the substantially tubular structure.
- 109. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being less than the second amount of alignment, the plurality of hoops being interconnected to form the substantially tubular structure.
- 136. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first amount of alignment being substantially equal to the second amount of alignment, the plurality of hoops being interconnected to form the substantially tubular structure.
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163. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and the plurality of radial arcs having a second amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first and second amounts of alignment being greater than a nominal alignment; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops.
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164. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts and a plurality of radial arcs, the plurality of radial struts having a first amount of alignment of the polymer chains comprising the polymeric material in a direction substantially parallel to the longitudinal axis and a plurality of radial arcs having a second amount of alignment of the polymeric chains comprising the polymeric material in a direction substantially parallel to the radial axis, the first and second amounts of alignment being greater than a nominal alignment and not equal to one another; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops.
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165. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts oriented substantially parallel to the longitudinal axis and a plurality of radial arcs oriented substantially parallel to the radial axis, the polymeric material having increased elongation at break regions in a direction substantially parallel to at least one of the longitudinal axis and the radial axis, the polymeric material comprising a predetermined molecular alignment in the regions of increased elongation at break resulting from being drawn in the range from greater than zero percent to about five hundred percent; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops.
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166. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts oriented substantially parallel to the longitudinal axis and a plurality of radial arcs oriented substantially parallel to the radial axis, the polymeric material having increased elongation at break regions in a direction substantially parallel to the at least one of the longitudinal axis and the radial axis, the polymeric material comprising a predetermined molecular alignment in the regions of increased elongation at break resulting from being drawn in the range from greater than zero percent to about five hundred percent and then relaxed to less than five hundred percent at a constant temperature; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops.
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167. A substantially tubular intraluminal medical device having a longitudinal axis and a radial axis, the device comprising:
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a plurality of hoops formed from a polymeric material, the plurality of hoops comprising a plurality of radial struts oriented substantially parallel to the longitudinal axis and a plurality of radial arcs oriented substantially parallel to the radial axis, the polymeric material having increased elongation at break regions in a direction substantially parallel to the at least one of the longitudinal axis and the radial axis, the polymeric material comprising a predetermined molecular alignment in the regions of increased elongation at break resulting from being drawn in the range from greater than zero percent to about five hundred percent at a first temperature, fixed and cooled to a second temperature, heated to about the first temperature and relaxed to about less than five hundred percent at a constant temperature; and a plurality of bridges formed from a polymeric material interconnecting the plurality of hoops.
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168. A substantially tubular intraluminal medical device comprising a plurality of elements formed from a polymeric material, wherein one or more elements comprises at least one high elongation at break region in a direction of the one or more elements, the polymeric material having a predetermined molecular alignment in the regions of increased elongation at break resulting from being heated and drawn in the direction of the one or more elements.
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169. A substantially tubular intraluminal medical device comprising a plurality of elements formed from a polymeric material, wherein one or more elements comprises at least one high elongation at break region in a direction of the one or more elements, the polymeric material having a predetermined molecular alignment in the regions of increased elongation at break resulting from being heated and drawn in the direction of the one or more elements, and then allowing the material to relax in the direction of the one or more elements.
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170. A substantially tubular intraluminal medical device comprising a plurality of elements formed from a polymeric material, wherein one or more elements comprises at least one high elongation at break region in a direction of the one or more elements, the polymeric material having a predetermined molecular alignment in the regions of increased elongation at break resulting from being heated and drawn in the direction of the one or more elements, fixing and cooling the polymeric material, heating the polymeric material and allowing the polymeric material to relax in the direction of the one or more elements.
Specification
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Current AssigneeDavid W. Overaker, Joseph H. Contiliano, Pallassana V. Narayanan, Qiang Zhang, Robert Burgermeister, Vipul Dave, Yufu Liu
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Original AssigneeDavid W. Overaker, Joseph H. Contiliano, Pallassana V. Narayanan, Qiang Zhang, Robert Burgermeister, Vipul Dave, Yufu Liu
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InventorsLi, Yufu, Zhang, Qiang, Contiliano, Joseph H., Dave, Vipul, Overaker, David W., Burgermeister, Robert, Narayanan, Pallassana V.
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Application NumberUS12/962,927Publication NumberTime in Patent OfficeDaysField of SearchUS Class Current623/1.16CPC Class CodesA61L 2300/236 Glycosaminoglycans, e.g. he...A61L 2300/41 Anti-inflammatory agents, e...A61L 2300/416 Anti-neoplastic or anti-pro...A61L 2300/418 Agents promoting blood coag...A61L 2300/42 Anti-thrombotic agents, ant...A61L 2300/43 Hormones, e.g. dexamethasoneA61L 27/26 Mixtures of macromolecular ...A61L 27/54 Biologically active materia...A61L 31/04 Macromolecular materialsA61L 31/128 containing other specific i...A61L 31/16 Biologically active materia...A61L 31/18 Materials at least partiall...A61P 29/00 Non-central analgesic, anti...A61P 7/02 Antithrombotic agents; Anti...A61P 9/10 for treating ischaemic or a...
