SURFACE TREATMENT OF BIOMEDICAL DEVICES

• US 20110152399A1
• Filed: 02/28/2011
• Published: 06/23/2011
• Est. Priority Date: 12/15/2006
• Status: Abandoned Application

• Current Assignee: Jeffrey G. Linhardt, Künzler, Jay F.
• Original Assignee: Jeffrey G. Linhardt, Künzler, Jay F.
• Inventors: Linhardt, Jeffrey G., Künzler, Jay F.
• Application Number:
  US13/036,402
• Publication Number:
  US 20110152399A1
• Time in Patent Office: Days
• US Class Current: 523/106
• CPC Class Codes: A61L 27/18 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/34 Macromolecular materials
• CPC Class Codes: A61L 27/50 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 29/085 Macromolecular materials
• CPC Class Codes: A61L 29/14 Materials characterised by their function or physical properties , e.g. lubricating compositions
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: C08J 2433/00 Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
• CPC Class Codes: C08J 7/0427 with only one layer of a composition containing a polymer binder with more layers C08J7/042
• CPC Class Codes: C08J 7/052 Forming heat-sealable coatings
• CPC Class Codes: C08J 7/056 Forming hydrophilic coatings
• CPC Class Codes: C08L 83/04 Polysiloxanes
• CPC Class Codes: C09D 133/02 Homopolymers or copolymers of acids; Metal or ammonium salts thereof
• CPC Class Codes: G02B 1/043 Contact lenses

Abstract

A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising a polymer or copolymer having one or more repeating units of the formula:

wherein R independently is a C₂-C₂₀ hydrocarbon radical and n is an integer of 2 to 5000.

Claims

1. A method for improving the wettability of a biomedical device, the method comprising the step of contacting a surface of the biomedical device with a composition comprising a polymer or copolymer having one or more repeating units of the formula:

2. The method of claim 1, wherein the biomedical device is a contact lens.

3. The method of claim 1, wherein the biomedical device is a silicone hydrogel contact lens.

4. The method of claim 1, wherein R is a C₂-C₆ straight chain or branched alkyl group.

5. The method of claim 1, wherein R is an ethyl or propyl group.

6. The method of claim 1, wherein the polymer or copolymer is obtained from the polymerization or copolymerization of a monomeric mixture comprising one or more C₂-C₆ straight chain, branched, and cyclic 2-alpha-alkyl acrylic acids.

7. The method of claim 6, wherein the monomeric mixture further comprises one or more hydrophilic monomers.

8. A surface modified biomedical device comprising a biomedical device having a coating on a surface thereof, the coating comprising a polymer or copolymer having one or more repeating units of the formula:

9. The surface modified biomedical device of claim 8, wherein the biomedical device is a contact lens.

10. The surface modified biomedical device of claim 8, wherein the biomedical device is a silicone hydrogel contact lens.

11. The surface modified biomedical device of claim 8, wherein R is a C₂-C₆ straight chain or branched alkyl group.

12. The surface modified biomedical device of claim 8, wherein R is an ethyl or propyl group.

13. The surface modified biomedical device of claim 8, wherein the polymer or copolymer is obtained from the polymerization or copolymerization of a monomeric mixture comprising one or more C₂-C₆ straight chain, branched, and cyclic 2-alpha-alkyl acrylic acids.

14. The surface modified biomedical device of claim 13, wherein the monomeric mixture further comprises one or more hydrophilic monomers.