PUMPING DEVICES, SYSTEMS AND METHODS FOR USE WITH MEDICAL FLUIDS INCLUDING COMPENSATION FOR VARIATIONS IN PRESSURE OR FLOW RATE

• US 20110152681A1
• Filed: 12/21/2010
• Published: 06/23/2011
• Est. Priority Date: 12/21/2009
• Status: Active Grant

• Current Assignee: Bayer Healthcare LLC (Bayer AG)
• Original Assignee: Bayer Healthcare LLC (Bayer AG)
• Inventors: Reilly, David M.
• Granted Patent: US 9,480,791 B2
• Time in Patent Office: Days
• US Class Current: 600/432
• CPC Class Codes: A61M 2005/14533 cam actuated
• CPC Class Codes: A61M 2206/22 eliminating pulsatile flows, e.g. by the provision of a dampening chamber
• CPC Class Codes: A61M 5/007 for contrast media
• CPC Class Codes: A61M 5/1422 with double acting or multiple pistons
• CPC Class Codes: A61M 5/1452 pressurised by means of pistons
• CPC Class Codes: A61M 5/16881 Regulating valves on-off valves, e.g. clamps A61M39/28

Abstract

A system for delivery of a medical fluid to a patient includes a pump system including a pressurizing unit to pressurize the medical fluid and a drive system in operative connection with the pressurizing unit. The pump system exhibits variation in pressure during operation. The system further includes a compensating system in fluid connection with the medical fluid pressurized by the pressurizing unit. The compensating system defines a displacement volume in fluid connection with the pressurized medical fluid that is altered in a predetermined manner to alter the variation in pressure. The compensating system can, for example, reduce pulsatility of pressure during flow.

Claims

1. A system for delivery of a medical fluid to a patient comprising:

a pump system comprising a pressurizing unit to pressurize the medical fluid and a drive system in operative connection with the pressurizing unit, the pump system exhibiting variation in pressure during operation; and

a compensating system in fluid connection with the medical fluid pressurized by the pressurizing unit, the compensating system defining a displacement volume in fluid connection with the pressurized medical fluid that is altered to alter the variation in pressure.

2. The system of claim 1 wherein the compensating system reduces pulsatility of pressure during flow.

3. The system of claim 2 wherein the compensating system comprises a moveable member in fluid connection with the pressurized medical fluid, the moveable member being moveable to alter the displacement volume.

4. The system of claim 3 wherein the moveable member is biased in a determined manner to oppose the force of the pressurized medical fluid upon the moveable member.

5. The system of claim 4 wherein the moveable member is biased by a biasing mechanism or by a compressible fluid.

6. The system of claim 5 wherein the biasing mechanism is a spring.

7. The system of claim 6 wherein the moveable member comprises a piston.

8. The system of claim 5 wherein the moveable member comprises a flexible element that is biased by a compressible fluid.

9. The system of claim 8 wherein the compensating system comprises a rigid conduit and the flexible element comprises a flexible conduit within a lumen of the rigid conduit, a compressible fluid being entrapped between the rigid conduit and the flexible conduit, the lumen of the flexible conduit being in fluid connection with the pressurized medical fluid.

10. The system of claim 9 wherein the lumen of the flexible conduit is in fluid connection with an outlet of the pump system.

11. The system of claim 3 wherein the pressurizing unit comprises a plurality of pressurizing members actuated in a timed manner by the drive system, and wherein the movable member is in operative connection with a drive mechanism adapted to move the moveable member, the drive mechanism moving the movable member in a manner dependent upon timing of actuation of the pressurizing members.

12. The system of claim 11 wherein the drive mechanism comprises a multi-lobed cam element that is rotated to time movement of the moveable member.

13. The system of claim 12 wherein the number of lobes of the multi-lobed cam element is determined by a number of the pressurizing members.

14. The system of claim 13 wherein the pump system comprises a rotatable timing shaft to actuate the pressurizing members in the timed manner and the multi-lobed cam element is coupled to the timing shaft.

15. The system of claim 14 wherein the moveable member comprises a piston slidably positioned within a chamber and forming a sealing engagement with an inner wall of the chamber.

16. The system of claim 14 wherein a rearwardmost position of the piston is adjustable within the chamber to adjust an extent to which the piston can alter the displacement volume.

17. The system of claim 16 wherein the piston is biased against the force of the pressurized medical fluid by a biasing mechanism.

18. The system of claim 17 wherein the biasing mechanism is a spring.

19. The system of claim 16 further comprising an abutment element to abut the piston and to adjust the rearwardmost position of the piston.

20. The system of claim 11 wherein the moveable member comprises a piston slidably positioned within a chamber and forming a sealing engagement with an inner wall of the chamber and an actuator system to control position of the piston within the chamber, the actuator system being in communicative connection with a control system.

21. The system of claim 1 wherein the compensating system is in fluid connection with an outlet channel within the pressurizing unit.

22. The system of claim 1 wherein the pressurizing unit is removable from connection with the drive system.

23. A compensating system for reducing variations in pressure of a fluid, comprising:

a rigid conduit defining a lumen;

a flexible conduit disposed within the lumen of the rigid conduit and defining an inlet adapted to place the flexible conduit in fluid connection with the fluid; and

a compressible fluid entrapped between the rigid conduit and the flexible conduit.

24. The compensating system of claim 23 wherein the flexible conduit further comprises an outlet, and wherein the flexible conduit is adapted to be placed in line with a flow of the fluid.