Microfluidic Device for Blood Dialysis
First Claim
Patent Images
1. A microfluidic device, comprising:
- (i) one or more First Channels, each First Channel having a height in the range of about 50 μ
m to about 500 μ
m, a width in the range of about 50 μ
m to about 900 μ
m, and a length in the range of about 3 cm to about 20 cm;
(ii) at least one Second Channel complementary to one or more of the First Channels; and
(iii) a filtration membrane separating the one or more First Channels from the at least one Second Channel.
1 Assignment
0 Petitions
Accused Products
Abstract
The invention provides microfluidic devices and methods of using such devices for filtering solutions, such as blood.
84 Citations
28 Claims
-
1. A microfluidic device, comprising:
-
(i) one or more First Channels, each First Channel having a height in the range of about 50 μ
m to about 500 μ
m, a width in the range of about 50 μ
m to about 900 μ
m, and a length in the range of about 3 cm to about 20 cm;(ii) at least one Second Channel complementary to one or more of the First Channels; and (iii) a filtration membrane separating the one or more First Channels from the at least one Second Channel. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26)
-
-
27. A wearable kidney augmentation device, comprising:
-
(i) a filtration component comprising; (a) at least one First Channel and at least one Second Channel complementary to the at least one First Channel; and (b) a filtration membrane separating the at least one First Channel from the at least one Second Channel;
wherein the at least one First Channel is configured to provide a fluid shear rate in the range of about 100 s−
1 to about 3000 s−
1 for blood at 37.0°
C.;(ii) a first access conduit affording fluid communication with an input end of the at least one First Channel; (iii) a first return conduit affording fluid communication with an output end of the at least one First Channel; and (iv) a second return conduit affording fluid communication with an output end of the at least one Second Channel.
-
-
28-31. -31. (canceled)
Specification