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Swallowable Drug Delivery Device and Methods of Drug Delivery

  • US 20110160699A1
  • Filed: 12/23/2010
  • Published: 06/30/2011
  • Est. Priority Date: 12/24/2009
  • Status: Active Grant
First Claim
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1. An ingestible device suitable for swallowing into a lumen of a gastrointestinal tract of a patient, the lumen having a lumen wall, the device comprising:

  • a capsule sized to pass through the intestinal tract;

    a therapeutic agent preparation disposable in the capsule, the preparation comprising at least one therapeutic agent, wherein the therapeutic agent preparation would chemically degrade or impose a deleterious effect on the patient if released within the lumen of the gastrointestinal tract; and

    an actuator coupled to the therapeutic agent preparation and having a first configuration and a second configuration, the preparation being retained within the capsule when the actuator is in the first configuration, wherein the preparation is advanced from the capsule and into the lumen wall by movement of the actuator from the first configuration to the second configuration such that the deleterious effect or chemical degradation of the therapeutic agent in the lumen is inhibited.

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