Oxidation Resistant Dentifrice Compositions

• US 20110165099A1
• Filed: 01/03/2011
• Published: 07/07/2011
• Est. Priority Date: 12/29/2004
• Status: Abandoned Application

• Current Assignee: Evangelia S. Arvanitidou, Michael Prencipe
• Original Assignee: Evangelia S. Arvanitidou, Michael Prencipe
• Inventors: Prencipe, Michael, Arvanitidou, Evangelia S
• Application Number:
  US12/983,460
• Publication Number:
  US 20110165099A1
• Time in Patent Office: Days
• US Class Current: 424/54
• CPC Class Codes: A61K 2800/28 Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
• CPC Class Codes: A61K 2800/43 Pigments; Dyes
• CPC Class Codes: A61K 2800/48 Thickener, Thickening system
• CPC Class Codes: A61K 2800/522 Antioxidants; Radical scavengers
• CPC Class Codes: A61K 8/19 containing inorganic ingredients
• CPC Class Codes: A61K 8/20 Halogens; Compounds thereof
• CPC Class Codes: A61K 8/21 Fluorides; Derivatives thereof
• CPC Class Codes: A61K 8/23 Sulfur; Selenium; Tellurium; Compounds thereof
• CPC Class Codes: A61K 8/25 Silicon; Compounds thereof
• CPC Class Codes: A61K 8/33 containing oxygen
• CPC Class Codes: A61K 8/347 Phenols
• CPC Class Codes: A61K 8/9789 Magnoliopsida [dicotyledons]
• CPC Class Codes: A61P 31/04 Antibacterial agents
• CPC Class Codes: A61Q 11/00 Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Abstract

Low water tooth pastes contain a variety of plant extracts. The oral or dentifrice compositions containing humectants, abrasive compounds, and a variety of plant extracts, such as rosemary and green tea extracts, along with an additional antioxidant component. Examples of antioxidants include stannous compounds, sodium meta-bisulfite, BHT, ammonium sulfate, and potassium stannate. The compositions are resistant to browning. The invention also provides methods for promoting oral health of a subject animal comprising applying a composition as discussed above to the oral surfaces of the animal.

Claims

1. An oral composition comprising

at least one humectant;

at least one abrasive compound;

at least one plant-derivable compound selected from the group consisting of flavonoids, catechins, polyphenols, and tannins; and

less than 10% by weight water.

2. A composition according to claim 1, comprising 0.001% to 5% by weight of a plant extract, wherein the plant is selected from the group consisting of rosemary, oregano, green tea, baikal skullcap, S. lateriflora, S. orthocalyx, grape seed, and grape skin.

3. A composition according to claim 2, comprising rosemary extract or green tea extract.

4. A composition according to claim 1, comprising a free B-ring flavonoid.

5. A composition according to claim 1, comprising an extract of a Scutellaria species.

6. A composition according to claim 2, comprising less than 6% by weight water.

7. A composition according to claim 2, further comprising an antioxidant generally recognized as safe.

8. A composition according to claim 2, further comprising an antioxidant selected from the group consisting of stannous compounds, stannate compounds, ammonium sulfates, BHT, and sodium metabisulfite.

9. A method for promoting oral health of a subject animal, comprising applying a composition according to claim 1 to the oral surfaces of the animal.

10. An oral composition comprising

1-70% by weight of a humectant;

1-70% by weight of at least one abrasive compound;

less than 10% by weight water; and

0.001-5% by weight of a plant extract comprising one or more flavonoid components.

11. A composition according to claim 10, comprising 0.05% to 1% of a plant extract, wherein the plant is selected from the group consisting of rosemary, oregano, green tea, baikal skullcap, S. lateriflora, S. orthocalyx, grape seed, and grape skin.

12. A composition according to claim 11, comprising rosemary extract or green tea extract.

13. A composition according to claim 11, comprising an extract of a Scutellaria species.

14. A composition according to claim 10, comprising less than 6% by weight water.

15. A composition according to claim 10, further comprising an antioxidant generally recognized as safe.

16. A composition according to claim 10, further comprising an antioxidant selected from the group consisting of stannous compounds, stannate compounds, ammonium sulfates, BHT, and sodium metabisulfite.

17. A composition according to claim 10, further comprising an anticalculus system comprising at least one phosphate compound and a anionic carboxylate component.

18. A composition according to claim 10, further comprising an antibacterial component comprising a halogenated diphenylether compound.

19. A composition according to claim 18, wherein the halogenated diphenylether compound comprises triclosan.

20. A method for promoting oral health of a subject animal, comprising applying a composition according to claim 10 to the oral surfaces of the animal.

21. A method for promoting oral health of a subject animal, comprising applying a composition according to claim 14 to the oral surfaces of the animal.

22. A method for reducing the extent of discoloration in a toothpaste, the toothpaste being formulated to contain at least one of rosemary extract, green tea extract, oregano extract, baikal skullcap extract, S. lateriflora extract, S. orthocalyx extract, grape seed extract, and grape skin extract, the extracts containing flavonoid, catechin, polyphenol, or tannin compounds that tend to oxidize and discolor the toothpaste composition over time, the method comprising at least one of

a) formulating the toothpaste to contain less than 10% by weight water;

and

b) adding to the toothpaste an amount effective to reduce discoloration of an antioxidant selected form the group consisting of stannous compounds, stannate compounds, ammonium sulfate, phenolic antioxidants, hydroquinone antioxidants, and sodium meta-bisulfite.

23. A method according to claim 22, comprising formulating the toothpaste to contain less than 6% by weight water.

24. A method according to claim 23, comprising adding 0.01-1% by weight of the antioxidant.

25. A method according to claim 22, wherein the toothpaste comprises rosemary extract or green tea extract.

26. A method according to claim 22, wherein the toothpaste formulation comprises an extract of a Scutellaria species.

27. A method according to claim 22, wherein the toothpaste composition comprises an antibacterial component comprising a halogenated diphenylether compound.

28. A composition according to claim 27, wherein the halogenated diphenylether compound comprises triclosan.