Super Sparger Microcarrier Beads and Precision Extrusion Deposited Poly-Epsilon-Caprolactone Structures for Biological Applications
0 Assignments
0 Petitions
Accused Products
Abstract
In on aspect, the invention includes a microcarrier bead having a porous three-dimensional core having (a) a polymeric porous three-dimensional body having porosity of about 15 to about 90% such that at least 99% of pores are interconnected and have diameters of at most 200 microns, (b) an outer protective layer and optionally (c) a filler. In another aspect, the invention includes a method of making an artificial scaffold wherein a scaffolding material is extruded into a coolant and thereby creating a porous material having a porosity of between 15-90% such that at least 99% of pores are interconnected and have diameters of at most 200 microns.
25 Citations
23 Claims
-
1-10. -10. (canceled)
-
11. A method for making an artificial scaffold having porosity of about 15 to about 90% such that at least 99% of pores are interconnected and have diameters of at most 200 microns, the method comprising:
-
providing a scaffolding material; providing a coolant having a thermal conductivity of greater than 0.026; and extruding the scaffolding material into the coolant and thereby making the artificial scaffold having a porous three-dimensional body wherein at least 99% of pores in the porous three-dimensional body are interconnected and lead to an external surface of the porous three-dimensional body and wherein pores have diameters of at most 200 microns. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
-
-
23-25. -25. (canceled)
Specification