HYDROGELS WITH RELEASE ELEMENT

• US 20110166492A1
• Filed: 09/23/2009
• Published: 07/07/2011
• Est. Priority Date: 09/24/2008
• Status: Active Grant

• Current Assignee: Solventum Intellectual Properties Company (Solventum Corp.)
• Original Assignee: 3M Innovative Properties Company (3M Company)
• Inventors: Jacobson, Richard L., Asmus, Robert A., Burton, Scott A., Holm, David R.
• Granted Patent: US 9,457,123 B2
• Time in Patent Office: Days
• US Class Current: 602/43
• CPC Class Codes: A61F 13/0256 characterized by the parametric properties of the adhesive
• CPC Class Codes: A61F 2013/00753 superabsorbent fabric of cloth
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 15/58 Adhesives
• CPC Class Codes: A61L 15/60 Liquid-swellable gel-forming materials, e.g. super-absorbents
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/602 Type of release, e.g. controlled, sustained, slow

Abstract

An adhesive hydrogel dressing as well as methods of applying the dressing to a patient. The dressing generally comprises an adhesive hydrogel pad, a backing layer, and an adhesive layer on the backing layer facing the hydrogel pad. The adhesive layer and backing layer form a perimeter around the hydrogel pad and hold the hydrogel pad in place on an application surface. A release element is in contact with at least a portion of the edge of the hydrogel pad proximate the area that the hydrogel pad and release liner separate during liner removal.

Claims

1-22. -22. (canceled)

23. An island dressing, comprising

a backing that comprises a first major surface;

an adhesive located on the first major surface of the backing;

a hydrogel island pad proximate the first major surface of the backing;

a release element along at least a portion of the edge of the hydrogel pad; and

a release liner;

wherein at least a portion of the edge of the hydrogel pad contacts the release element proximate the area that the hydrogel pad and release liner separate during liner removal.

24. The island dressing of claim 23, wherein the average maximum peel force to initiate separation of an one-inch wide hydrogel pad and a release liner without the release element is at least 25% greater than the average maximum peel force of the hydrogel pad and the release liner with a release element, when measured by the T-peel Test Method performed after conditioning the island dressing for one week at 50 degrees C.

25. The island dressing of claim 23, wherein the hydrogel pad comprises less than 45% water.

26. The island dressing of claim 23, wherein the release element contacts at least a portion of the backing.

27. The island dressing of claim 26, wherein the release element contacts at least a portion of the backing and is attached to at least a portion of the backing.

28. The island dressing of claim 23, wherein the release element comprises a layer of adhesive on the skin facing surface of the release element that exhibits less tack than the adhesive located on the first major surface of the backing.

29. The island dressing of claim 23, wherein the hydrogel pad is attached to the adhesive on the first major surface of the backing.

30. The island dressing of claim 23, wherein the release element is comprised of a polymer film, a porous non-woven fabric, or a porous knitted fabric.

31. The island dressing of claims 23, wherein the hydrogel comprises

a first polymer comprising a cross-linked poly (N-vinyl) lactam;

a swelling agent; and

a second modifying polymer swellable in the swelling agent;

wherein the first polymer forms a pressure sensitive adhesive in the presence of the swelling agent; and

wherein the second modifying polymer and the swelling agent reduce the adhesiveness of the first polymer while at least maintaining the cohesion of the composition.

32. The island dressing of claim 23, further comprising an antimicrobial agent.

33. The island dressing of claim 31 wherein the poly (N-vinyl)lactam is selected from the group consisting of poly N-vinyl-2-pyrrolidone, poly N-vinyl-2-valerolactam, poly N-vinyl-2-caprolactam, and combinations of the foregoing.

34. The island dressing of claim 31 wherein the swelling agent is selected from the group consisting of monohydric alcohols;

polyhydric alcohols;

glycerol;

polyglycerols;

sorbitol;

polyhydric alcohol ethoxylates;

methoxides of polyethylene glycol;

methoxides of polyhydric alcohol ethoxylates; and

combinations of the foregoing.

35. The island dressing of claim 31, wherein the swelling agent is greater than 50% of the total weight of the composition.

36. The island dressing of claim 31 wherein the second modifying polymer comprises a polysaccharide, polysaccharide derivatives, acrylate, acrylate derivatives, cellulose, cellulose derivatives, and combinations thereof.

37. The island dressing of claim 36 wherein the second modifying polymer is selected from the group consisting of hydroxypropyl guar;

guar gum;

hydroxyethyl cellulose;

hydroxypropyl cellulose;

hydroxypropyl methylcellulose;

polymeric quaternary ammonium salt of hydroxyethyl cellulose reacted with trialkyl ammonium substituted epoxide;

copolymers of hydroxyethyl cellulose and diallyldimethyl ammonium chloride; and

derivatives and combinations of the foregoing.

38. The island dressing of claim 31 wherein:

the first polymer is present in the composition in an amount between 5% and 45% by weight;

the swelling agent is present in an amount of at least 55% by weight; and

the second modifying polymer is present in an amount between 0.1% and 40% by weight.

39. The island dressing of claim 31 wherein first polymer is poly N-vinyl-2-pyrrolidone;

the swelling agent is triglycerol;

the second polymer is selected from the group consisting of hydroxypropyl guar;

guar gum;

hydroxyethyl cellulose;

hydroxypropyl cellulose;

hydroxypropyl methylcellulose;

polymeric quaternary ammonium salt of hydroxyethyl cellulose reacted with trialkyl ammonium substituted epoxide;

copolymers of hydroxyethyl cellulose and diallyldimethyl ammonium chloride; and

derivatives and combinations of the foregoing; and

the antimicrobial agent is chlorhexidine gluconate.