DIALYSIS SYSTEMS AND METHODS HAVING DISPOSABLE CASSETTE AND INTERFACE THEREFORE

• US 20110166507A1
• Filed: 03/14/2011
• Published: 07/07/2011
• Est. Priority Date: 07/05/2007
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Childers, Robert W., Hopping, Peter A.
• Granted Patent: US 8,328,758 B2
• Time in Patent Office: Days
• US Class Current: 604/28
• CPC Class Codes: A61M 1/152 Details related to the interface between cassette and machine
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/154 with sensing means or components thereof
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 1/166 Heating for sterilisation A61M1/1686
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/284 Continuous flow peritoneal dialysis [CFPD]
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 1/341 by measuring the filtrate rate or volume
• CPC Class Codes: A61M 2205/122 using evacuated interfaces to enhance contact
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3317 Electromagnetic, inductive or dielectric measuring means
• CPC Class Codes: A61M 2205/3324 PH measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2205/3368 : Temperature

Abstract

A medical fluid flow control system comprises an interface including a pump actuator port and a pump seal port, a membrane gasket including a pump actuation area and a pump aperture, and a pumping cassette including a flexible sheet and defining a pump chamber, a pump portion of the flexible sheet covering the pump chamber. The pump seal port is operable with the pump aperture to seal the pump portion of the flexible sheet to the pump actuation area of the membrane gasket and the pump actuator port is configured to move the pump portion of the flexible sheet and the pump actuation area of the membrane gasket at the pump chamber of the cassette.

Claims

1. A medical fluid flow control system comprising:

an interface including a pump actuator port and a pump seal port;

a membrane gasket including a pump actuation area and a pump aperture;

a pumping cassette including a flexible sheet and defining a pump chamber, a pump portion of the flexible sheet covering the pump chamber;

wherein the pump seal port is operable with the pump aperture to seal the pump portion of the flexible sheet to the pump actuation area of the membrane gasket; and

wherein the pump actuator port is configured to move the pump portion of the flexible sheet and the pump actuation area of the membrane gasket at the pump chamber of the cassette.

2. The medical fluid flow control system of claim 1, wherein the pump chamber of the cassette has a shape at least substantially similar to a shape of the pump area of the membrane gasket.

3. The medical fluid flow control system of claim 1, wherein the pump actuator port allows a negative pressure to be applied through the pump actuator port to move the pump portion of the flexible sheet and the pump actuation area of the membrane gasket to cause a volume of fluid to be pulled into the pump chamber of the pumping cassette.

4. The medical fluid flow control system of claim 1, wherein the pump actuator port allows a positive pressure to be applied through the pump actuator port to move the pump portion of the flexible sheet and the pump actuation area of the membrane gasket to cause a volume of fluid to be pushed out of the pump chamber of the pumping cassette.

5. The medical fluid flow control system of claim 1, the interface including a pump area which mates with the pump actuation area of the gasket.

6. The medical fluid flow control system of claim 1, wherein the pump seal port allows negative pressure to be applied through the pump seal port to seal the flexible sheet of the pumping cassette.

7. The medical fluid flow control system of claim 1, wherein at least one of (i) the pump seal port allows positive pressure to be applied through the pump seal port to push the pumping cassette away from the interface, and (ii) the pump actuator port allows positive pressure to be applied through the pump actuator port to push the pumping cassette away from the interface.

8. The medical fluid flow control system of claim 1, wherein the interface includes a pump area mating with the membrane gasket pump actuation area, the interface pump area including the pump actuator port and the pump seal port.

9. The medical fluid flow control system of claim 1, wherein the pump actuation area of the membrane gasket includes a blind section that covers the pump actuator port of the interface.

10. The medical fluid flow control system of claim 1, which includes a pressure sensor monitoring a negative pressure, and a logic implementer operable with an output of the pressure sensor to determine if a leak associated with one of the following has occurred (i) the pump actuation area of the membrane gasket and (ii) a portion of the flexible sheet of the pumping cassette mated with the pump actuation area of the membrane gasket.

11. A medical fluid flow control system comprising:

an interface including a valve actuator port and a valve seal port;

a membrane gasket including a valve actuation area and a valve aperture;

a pumping cassette including a flexible sheet and defining a valve chamber, a valve portion of the flexible sheet covering the valve chamber;

wherein the valve seal port is operable with the valve aperture to seal the valve portion of the flexible sheet to the valve actuation area of the membrane gasket; and

wherein the valve actuator port is configured to move the valve portion of the flexible sheet and the valve actuation area of the membrane gasket at the valve chamber of the cassette.

12. The medical fluid flow control system of claim 11, wherein the valve seal port allows negative pressure to be applied through the valve seal port to seal the flexible sheet of the pumping cassette.

13. The medical fluid flow control system of claim 11, wherein the valve actuator port allows negative pressure to be applied through the valve actuator port to allow fluid to flow through a valve of the pumping cassette.

14. The medical fluid flow control system of claim 11, wherein the valve actuation area of the membrane gasket includes a blind section which covers the valve actuator port of the interface.

15. The medical fluid flow control system of claim 11, wherein at least one of (i) the valve seal port allows positive pressure to be applied through the valve seal port to push the pumping cassette away from the interface, and (ii) the valve actuator port allows positive pressure to be applied through the valve actuator port to push the pumping cassette away from the interface.

16. The medical fluid flow control system of claim 11, which includes a pressure sensor monitoring a negative pressure, and a logic implementer operable with an output of the pressure sensor to determine if a leak associated with one of the following has occurred (i) the valve actuation area of the membrane gasket and (ii) a portion of the flexible sheet of the pumping cassette mated with the valve actuation area of the membrane gasket.

17. A method for controlling fluid flow in a medical fluid control system comprising:

applying negative pressure through a seal port of an interface to seal a flexible sheet of a pumping cassette to a membrane gasket;

applying pressure through a valve actuator port of the interface to move a valve portion of the flexible sheet and a valve actuation area of the membrane gasket;

applying pressure through a pump actuator port of the interface to move a pump portion of the flexible sheet and a pump actuation area of the membrane gasket.

18. The method for controlling fluid flow in a medical fluid control system of claim 17 including applying negative pressure through the pump actuator port to move the flexible sheet and the pump actuation area of the membrane gasket and cause a volume of fluid to be pulled out of a pump chamber of the pumping cassette.

19. The method for controlling fluid flow in a medical fluid control system of claim 17 including applying a positive pressure through the pump actuator port to move the flexible sheet and the pump actuation area of the membrane gasket and cause a volume of fluid to be pushed into a pump chamber of the pumping cassette.

20. The method for controlling fluid flow in a medical fluid control system of claim 17 including applying positive pressure through at least one of (i) the seal port and (ii) the valve actuator port to push the pumping cassette away from the interface.

21. The method for controlling fluid flow in a medical fluid control system of claim 17 wherein applying negative pressure through a seal port of an interface includes applying negative pressure through a valve seal port of the interface and applying negative pressure through a pump seal port of the interface.

22. The method for controlling fluid flow in a medical fluid control system of claim 17 including applying positive pressure through a valve actuator port of the interface to move a valve portion of the flexible sheet and a valve actuation area of the membrane gasket to close a valve chamber of the pumping cassette.