SYSTEMS AND METHODS FOR CORRECTING HIGH ORDER ABERRATIONS IN LASER REFRACTIVE SURGERY

• US 20110166558A1
• Filed: 03/18/2011
• Published: 07/07/2011
• Est. Priority Date: 04/18/2003
• Status: Active Grant

• Current Assignee: Amo Manufacturing Usa, Llc (Johnson & Johnson)
• Original Assignee: Amo Manufacturing Usa, Llc (Johnson & Johnson)
• Inventors: Liang, Junzhong, Dai, Guangming
• Granted Patent: US 10,238,537 B2
• Time in Patent Office: Days
• US Class Current: 606/5
• CPC Class Codes: A61F 2009/00844 Feedback systems
• CPC Class Codes: A61F 2009/00846 Eyetracking
• CPC Class Codes: A61F 2009/00848 based on wavefront
• CPC Class Codes: A61F 2009/00857 considering biodynamics
• CPC Class Codes: A61F 2009/00872 Cornea
• CPC Class Codes: A61F 2009/0088 based on wavefront
• CPC Class Codes: A61F 2009/00897 Scanning mechanisms or algorithms
• CPC Class Codes: A61F 9/008 using laser
• CPC Class Codes: A61F 9/00806 Correction of higher orders
• CPC Class Codes: A61F 9/00817 Beam shaping with masks

Abstract

Optical correction methods, devices, and systems reduce optical aberrations or inhibit refractive surgery induced aberrations. Error source control and adjustment or optimization of ablation profiles or other optical data address high order aberrations. A simulation approach identifies and characterizes system factors that can contribute to, or that can be adjusted to inhibit, optical aberrations. Modeling effects of system components facilitates adjustment of the system parameters.

Claims

1. A system for inhibiting an induced aberration resulting from refractive surgery, the system comprising:

an input device that accepts a target optical surface shape;

a determination module that determines a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters, wherein the set of refractive surgery system parameters is embodied within a data file;

a comparison module that compares the target optical surface shape and the model optical surface shape to determine an aberration induced by the set of refractive surgery system parameters embodied within the data file; and

an adjustment module that adjusts the set of refractive surgery system parameters embodied within the data file so as to inhibit the induced aberration.

2. The system of claim 1, wherein the set of refractive surgery system parameters comprises at least one member selected from the group consisting of a wavefront device variable, a laser ablation profile variable, a laser registration and tracking system variable, a microkeratome variable, and a healing effect variable.

3. The system of claim 1, wherein the adjustment module comprises a metric selected from the group consisting of an accuracy variable, a heating variable, and a treatment time variable.

4. The system of claim 3, wherein the accuracy variable is based on a root mean squares error factor, or wherein the heating variable is based on a temperature factor, or wherein the treatment time variable is based on an ablation time factor.

5. The system of claim 1, wherein the aberration comprises a high order aberration.

6. The system of claim 1, wherein the target optical surface shape is configured to address a low order aberration.

7. The system of claim 2, wherein the wavefront device variable comprises a member selected from a group consisting of a spot identification factor, an accommodation factor, and a reconstruction factor.

8. The system of claim 7, wherein the reconstruction factor comprises a member selected from the group consisting of uncompensated residual error portion, a measurement error portion, and a remaining error portion.

9. The system of claim 2, wherein the laser ablation profile variable comprises a member selected from the group consisting of a pulse size factor, a spot size variability factor, a beam uniformity factor, and an ablation rate factor.

10. The system of claim 2, wherein the microkeratome variable comprises a member selected from the group consisting of a central flattening and peripheral thickening effect factor and a hinge effect factor.

11. The system of claim 2, wherein the laser registration and tracking system variable comprises a member selected from the group consisting of a registration factor, a linear tracking factor, and a torsional tracking factor.

12. The system of claim 2, wherein the wavefront device variable is configured to address a high order aberration.

13. The system of claim 2, wherein the wavefront device variable comprises a gridsize factor adjusted to about 100 μ

m, and the laser ablation profile variable comprises a flying spot scanning factor adjusted to range from about 1 mm to about 1.6 mm.

14. The system of claim 13, wherein the flying spot scanning factor is about 1.5 mm.

15. The system of claim 2, wherein the wavefront device variable comprises a spot identification error adjusted to about 0.05 microns;

or

wherein the wavefront device variable comprises a wavefront reconstruction error adjusted to about 0.05 microns;

or

wherein the wavefront device variable comprises an accommodation error adjusted to about 0.25D, equivalent to 0.325 microns RMS error for a 6 mm pupil.

16. The system of claim 2, wherein the microkeratome variable comprises an induced positive spherical aberration adjusted to between about 0.1 microns and about 0.3 microns;

or

wherein the microkeratome variable comprises a coma in the direction of the microkeratome hinge adjusted to an amount between 0.1 microns and 0.3 microns.

17. The system of claim 2, wherein the healing effect variable comprises a Gaussian kernel adjusted to about 2 micron in height and about 0.5 mm in full width at half maximum (FWHM).

18. The system of claim 1, wherein the adjustment module is configured to adjust the set of refractive surgery system parameters such that a post-operative total high order RMS of about 0.3 μ

m is achieved.

19. The system of claim 18, wherein a pre-operative total high order RMS is about 0.3 μ

m.

20. The system of claim 18, wherein each component of the total high order RMS does not exceed about 0.13 μ

m.

21. The system of claim 1, wherein the adjustment module is configured to adjust the set of refractive surgery system parameters such that a post-operative total high order RMS of about 0.1 μ

m is achieved.

22. The system of claim 21, wherein a pre-operative total high order RMS is about 0.3 μ

m.

23. The system of claim 21, wherein each component of the total high order RMS does not exceed about 0.045 μ

m.

24. The system of claim 2, wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a registration accuracy adjusted to less than 10 μ

m in both the vertical and horizontal directions and a rotational error adjusted to less than 0.5°

;

or

wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a registration accuracy adjusted to less than 10 μ

m in both the vertical and horizontal directions and a rotational error adjusted to less than 0.5°

;

or

wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a tracking accuracy adjusted to less than 20 μ

m in both the vertical and horizontal directions, a latency time adjusted to less than 10 ms, and a tracking speed adjusted to 60 Hz or greater;

or

wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a tracking accuracy adjusted to less than 5 μ

m in both the vertical and horizontal directions, a latency time adjusted to less than 5 ms, and a tracking speed adjusted to 200 Hz or greater;

or

wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a cyclo-torsional tracking angular accuracy adjusted to 0.5°

or better;

or

wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a cyclo-torsional tracking angular accuracy adjusted to 0.25°

or better;

or

wherein the laser ablation profile variable comprises a variable spot scanning factor, and the laser registration and tracking system variable comprises a laser energy fluctuation adjusted to less than 4%;

or

wherein the laser ablation profile variable comprises a flying spot scanning factor, and the laser registration and tracking system variable comprises a laser energy fluctuation adjusted to less than 2%.

25. The system of claim 2, wherein the target optical surface shape comprises a set of 6-order Zernike polynomials, and the set of refractive surgery system parameters is adjusted such that each component of a post-operative total high order RMS does not exceed about 0.025 μ

m;

or

wherein the target optical surface shape comprises a set of 6-order Zernike polynomials, and the set of refractive surgery system parameters is adjusted such that each component of a post-operative total high order RMS does not exceed about 0.0087 μ

m.

26. The system of claim 1, wherein the adjustment module is configured to adjust the set of refractive surgery system parameters such that a post-operative total high order RMS is substantially equivalent to a pre-operative total high order RMS;

or

wherein the adjustment module is configured to adjust the set of refractive surgery system parameters such that a post-operative total high order RMS is less than a pre-operative total high order RMS;

or

wherein the adjustment module is configured to adjust the set of refractive surgery system parameters such that a post-operative total high order RMS is about one third the amount of a pre-operative total high order RMS.

27. A system for altering aberration distribution resulting from optical surface refractive surgery, the system comprising:

an input device that accepts a target optical surface shape;

a determination module that determines a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters, wherein the set of refractive surgery system parameters is embodied within machine readable data of a tangible storage media;

a comparison module that compares the target optical surface shape and the model optical surface shape to determine an aberration distribution; and

an adjustment module that adjusts the set of refractive surgery system parameters embodied within machine readable data of the tangible storage media so as to alter the aberration distribution.

28. A system for inhibiting a refractive surgery induced aberration, the system comprising:

an input device that accepts a target optical surface shape;

a determination module that determines a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters, the model optical surface shape having an aberration, wherein the set of refractive surgery system parameters is embodied within a storage module;

an adjustment module that adjusts the set of refractive surgery system parameters embodied within the storage module so as to inhibit the aberration.

29. A system for adjusting a set of refractive surgery system parameters for use in a refractive treatment, the system comprising:

an input device that accepts a target optical surface shape;

a determination module that determines a model optical surface shape based on the target optical surface shape and a set of refractive surgery system parameters;

a comparison module that compares the target optical surface shape and the model optical surface shape to determine an aberration induced by the set of refractive surgery system parameters;

an adjustment module that adjusts the set of refractive surgery system parameters so as to inhibit the induced aberration; and

a treatment module that administers the refractive treatment to a patient, wherein the refractive treatment is based on the adjusted set of refractive surgery system parameters.