CARDIOVASCULAR ANALYZER

• US 20110172505A1
• Filed: 09/30/2009
• Published: 07/14/2011
• Est. Priority Date: 10/01/2008
• Status: Active Grant

• Current Assignee: Cleveland Heart Coronyzer, LLC
• Original Assignee: Irumedi Co., Ltd.
• Inventors: Hyeon, Seog San, Kim, Kwang Tae
• Granted Patent: US 8,771,195 B2
• Time in Patent Office: Days
• US Class Current: 600/301
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/026 Measuring blood flow A61B3/1233, A61B3/1241 take precedence
• CPC Class Codes: A61B 5/7278 Artificial waveform generation or derivation, e.g. synthesising signals from measured signals A61B5/327 takes precedence

Abstract

The present invention relates to a cardiovascular diagnostic system which enables early detection of cardiovascular diseases and defines their causes. Unlike known electrocardiographs, the cardiovascular diagnosis system can further measure elastic coefficient of blood vessels (the degree of arteriosclerosis), blood vessel compliance, blood flow, and blood flow resistance and velocity in blood vessel branches of the right and left coronary arteries. The elastic coefficient shows organic changes to blood vessels. The compliance shows organic and functional changes of blood vessels simultaneously. The blood flow shows blood flow resistance.

Claims

27. The cardiovascular analyzer of claim 26,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

1. A cardiovascular analyzer comprising:

a bio-signal measurement system including a bio-signal measuring sensor unit which comprises an electrocardiogram (ECG) sensor, a phonocardiogram (PCG) sensor and an accelerated plethysmogram (APG) sensor, and a bio-signal reception and process unit which is connected to each of the sensors of the bio-signal measuring sensor unit for receiving and processing bio-signals measured by the sensors; and

an analysis indicator calculation system including a main processing unit which is connected to the bio-signal reception and process unit for communicating and calculating biodynamic indicators of a coronary artery from the bio-signals, an input unit which is connected to the main processing unit for receiving control commends of user, and an output unit which is connected to the main processing unit for displaying the calculated results,

wherein the main processing unit synthesizes an aortic arch internal pressure curve P from the bio-signals measured by the bio-signal measurement system and calculates the biodynamic indicators from an area of the aortic arch internal pressure curve P.

2. The cardiovascular analyzer of claim 1,

wherein the bio-signal reception and process unit comprises:

a microcontroller which controls to process the bio-signals received from the bio-signal measuring unit and to transmit processed bio-signals to the main processing unit;

a multi-signal selector which selects one of the bio-signals received from the ECG sensor, the PCG sensor and the APG sensor by a control signal of the microcontroller;

a noise eliminator and signal amplifier which eliminates noises and/or controls amplification degree of the bio-signal selected by the multi-signal sensor by a control signal of the microcontroller;

a signal switcher which receives the bio-signals from the noise eliminator and signal amplifier and selects one of the bio-signals to meet the control commands of the input unit or of embedded program in the main processing unit by a control signal of the microcontroller;

a sample holder which samples and holds the bio-signal selected by the signal switcher by a control signal of the microcontroller; and

an A/D converter which converts a holding bio-signal of the sample holder to a digital bio-signal and sends to the microcontroller by a control signal of the microcontroller.

3. The cardiovascular analyzer of claim 1,

wherein the APG sensor is a cuff pulse wave sensor, a carotid artery pulse wave sensor or a femoral artery pulse wave sensor;

and

wherein the bio-signal measurement system obtains an ECG waveform, a PCG waveform and an APG waveform synchronously by the bio-signal measuring sensor unit.

4. The cardiovascular analyzer of claim 3, wherein the carotid artery pulse wave sensor and the femoral artery pulse wave sensor are the same pressure sensor;

and

wherein the cuff pulse wave sensor is a cuff sphygmomanometer equipped with a pressure sensor.

5. The cardiovascular analyzer of claim 4,

wherein the cuff pulse wave sensor comprises a rubber hose which is connected to a air pouch of the cuff sphygmomanometer, a branch hose which is connected to the rubber tube, and an adaptor which is connected to an exit of the branch hose;

and

wherein the adaptor is assembled to an opening part of a sensor having the same structure as the carotid artery pulse wave sensor or the femoral artery pulse wave sensor.

6. The cardiovascular analyzer of claim 1,

wherein the main processing unit is programmed with the steps of:

(1) ordering the bio-signal measurement system to measure the bio-signals and receiving the bio-signals from the bio-signal measurement system;

(2) analyzing waveforms from the received bio-signals and synthesizing the aortic arch internal pressure curve P from the analyzed waveforms; and

(3) calculating the biodynamic indicators from the area of the synthesized aortic arch internal pressure curve P and displaying the results of cardiovascular analysis.

7. The cardiovascular analyzer of claim 6,

wherein the step 3 comprises:

calculating blood flow volumes S_l and S_r of the left and right coronary arteries from the basic data including the area of the aortic arch internal pressure curve P;

calculating compliances C_l and C_r and blood flow resistances R_l and R_r of the left and right coronary arteries from the aortic arch internal pressure curve P and the blood flow volumes S_l and S_r of the left and right coronary arteries; and

transmitting the results of cardiovascular analysis to the output unit for showing the calculated compliances C_l and C_r and the calculated blood flow resistances R_l and R_r of the left and right coronary arteries on one C-R chart.

8. The cardiovascular analyzer of claim 7,

wherein the step 3 further comprises:

calculating arterial stiffness As_l and As_r of the left and right coronary arteries from the blood flow volumes S_l and S_r, the compliances C_l and C_r and the blood flow resistances R_l and R_r of the left and right coronary arteries and transmitting to the output unit.

9. The cardiovascular analyzer of claim 7,

wherein the step 3 further comprises:

calculating blood flow velocities V_l and V_r of the left and right coronary arteries from the aortic arch internal pressure curve P and the compliances C_l and C_r of the left and right coronary arteries and transmitting to the output unit.

10. The cardiovascular analyzer of claim 7,

wherein the blood flow volumes S_l and S_r, the compliances C_l and C_r and the blood flow resistances R_l and R_r of the left and right coronary arteries are calculated by the equations of:

the blood flow volume S_l of the left coronary artery is

11. The cardiovascular analyzer of claim 10,

wherein the coefficient K is calculated by Equation 8;

wherein the coefficient K₁ is related to a blood flow volume flowing from an entrance of the coronary artery to the right coronary artery and is 0.12˜

0.15; and

wherein the coefficient K₂ is a tissue internal pressure coefficient and is 0.7˜

0.75.

12. The cardiovascular analyzer of claim 8,

wherein the arterial stiffness As_l and As_r of the left and right coronary arteries are calculated by the equations of:

the arterial stiffness As_l of the left coronary artery is

13. The cardiovascular analyzer of claim 9,

wherein the blood flow velocities V_l and V_r of the left and right coronary arteries are calculated by the equations of:

the blood flow velocity V_l of the left coronary artery is

14. The cardiovascular analyzer of claim 6,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

15. The cardiovascular analyzer of claim 14,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

16. The cardiovascular analyzer of claim 15,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

17. The cardiovascular analyzer of claim 16,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

18. The cardiovascular analyzer of claim 17,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

19. The cardiovascular analyzer of claim 17,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

20. The cardiovascular analyzer of claim 18,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

21. The cardiovascular analyzer of claim 2,

wherein the APG sensor is a cuff pulse wave sensor, a carotid artery pulse wave sensor or a femoral artery pulse wave sensor;

and

wherein the bio-signal measurement system obtains an ECG waveform, a PCG waveform and an APG waveform synchronously by the bio-signal measuring sensor unit.

22. The cardiovascular analyzer of claim 21,

wherein the carotid artery pulse wave sensor and the femoral artery pulse wave sensor are the same pressure sensor;

and

wherein the cuff pulse wave sensor is a cuff sphygmomanometer equipped with a pressure sensor.

23. The cardiovascular analyzer of claim 22,

wherein the cuff pulse wave sensor comprises a rubber hose which is connected to a air pouch of the cuff sphygmomanometer, a branch hose which is connected to the rubber tube, and an adaptor which is connected to an exit of the branch hose;

and

wherein the adaptor is assembled to an opening part of a sensor having the same structure as the carotid artery pulse wave sensor or the femoral artery pulse wave sensor.

24. The cardiovascular analyzer of one of claim 7,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

25. The cardiovascular analyzer of claim 24,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

28. The cardiovascular analyzer of claim 25,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

29. The cardiovascular analyzer of claim 27,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

30. The cardiovascular analyzer of claim 28,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

31. The cardiovascular analyzer of one of claim 8,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

32. The cardiovascular analyzer of claim 31,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

33. The cardiovascular analyzer of claim 32,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

34. The cardiovascular analyzer of claim 33,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

35. The cardiovascular analyzer of claim 34,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

36. The cardiovascular analyzer of claim 34,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

37. The cardiovascular analyzer of claim 35,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

38. The cardiovascular analyzer of one of claim 9,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

39. The cardiovascular analyzer of claim 38,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

40. The cardiovascular analyzer of claim 39,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

41. The cardiovascular analyzer of claim 40,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

42. The cardiovascular analyzer of claim 41,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

43. The cardiovascular analyzer of claim 41,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

44. The cardiovascular analyzer of claim 42,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

45. The cardiovascular analyzer of one of claim 10,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

46. The cardiovascular analyzer of claim 45,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

47. The cardiovascular analyzer of claim 46,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

48. The cardiovascular analyzer of claim 47,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

49. The cardiovascular analyzer of claim 48,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

50. The cardiovascular analyzer of claim 48,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

51. The cardiovascular analyzer of claim 49,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

52. The cardiovascular analyzer of one of claim 11,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

53. The cardiovascular analyzer of claim 52,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

54. The cardiovascular analyzer of claim 53,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

55. The cardiovascular analyzer of claim 54,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

56. The cardiovascular analyzer of claim 55,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

57. The cardiovascular analyzer of claim 55,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

58. The cardiovascular analyzer of claim 56,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

59. The cardiovascular analyzer of one of claim 12,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

60. The cardiovascular analyzer of claim 59,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

61. The cardiovascular analyzer of claim 60,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

62. The cardiovascular analyzer of claim 61,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

63. The cardiovascular analyzer of claim 62,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

64. The cardiovascular analyzer of claim 62,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

65. The cardiovascular analyzer of claim 63,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

66. The cardiovascular analyzer of one of claim 13,

wherein the waveform analysis of the received bio-signals in the step 2 comprises:

finding feature points, including systolic upstroke point, systolic peak point, incisura point, diastolic peak point and diastolic end point, of the aortic arch internal pressure curve P by analyzing ECG signals and PCG signals measured by the ECG sensor and the PCG sensor of the bio-signals measurement system, respectively;

finding high frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by a cuff pulse wave sensor, as the APG sensor of the bio-signals measurement system, which is pressurized above the systolic blood pressure;

finding low frequency elements of the aortic arch internal pressure curve P by analyzing Cuff-APG pulse waves measured by the cuff pulse wave sensor which is depressurized below the diastolic blood pressure; and

finding a time-frequency intensity of the aortic arch internal pressure curve P by analyzing APG pulse waves of the left and right carotid arteries measured by a carotid artery pulse wave sensor as the APG sensor of the bio-signals measurement system, and

wherein the synthesis of the aortic arch internal pressure curve P is based on the basic information including the analyzed data of Cuff-APG pulse waves at the systole and the diastole and the analyzed data of APG pulse waves of the left and right carotid arteries.

67. The cardiovascular analyzer of claim 66,

wherein the main processing unit is further programmed with the steps of:

displaying an initial screen including a search menu window, a patient information window, a test and diagnosis window and a test result window in the output unit before the step 1;

receiving and saving the information of patient if a registration command for new patient is received in the initial screen, otherwise, receiving an opening command to open a registered patient file;

displaying a patient list in the registered patient file on the test result window if the opening command is received and receiving a signal for selecting a patient and new information of the selected patient, otherwise, displaying the initial screen continuously; and

displaying the information of new patient or the selected patient on the patient information window and receiving a test and diagnosis command,

wherein the information of new patient or the selected patient comprises a personally identified information and body information including one or more of height, weight, blood pressure and race.

68. The cardiovascular analyzer of claim 67,

wherein the measurement and reception of the bio-signals in the step 1 comprises:

(1-1) displaying a command selection window for the bio-signal measurement if a test command is received from the test and diagnosis window, otherwise, keeping the previous state;

(1-2-1) receiving ECG, PCG and high frequency APG waveforms measured by the ECG sensor, the PCG sensor and a pressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a systolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-2) receiving ECG, PCG and low frequency APG waveforms measured by the ECG sensor, the PCG sensor and a depressurized cuff pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of a diastolic pulse wave is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-3) receiving ECG, PCG and left carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the left carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-4) receiving ECG, PCG and right carotid artery APG waveforms measured by the ECG sensor, the PCG sensor and a carotid artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the right carotid artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command;

(1-2-5) receiving ECG, PCG and femoral artery APG waveforms measured by the ECG sensor, the PCG sensor and a femoral artery pulse wave sensor as the APG sensor of the bio-signal measuring sensor unit and displaying on the test result window if the measurement command of the femoral artery is received from the command selection window, otherwise, keeping the previous state as a standby step for receiving a bio-signal measurement command; and

(1-3) capturing a screen showing a selected ideal waveform among the waveforms displayed on the test result window and saving if a waveform selection command is received after each of the steps 1-2-1 to 1-2-5, otherwise, keeping the measurement and displaying the measured waveforms continuously.

69. The cardiovascular analyzer of claim 68,

wherein the waveform analysis of the received bio-signals and the synthesis of the aortic arch internal pressure curve P in the step 2 comprise:

(2-1) displaying an analysis menu window if an analysis command is received from the test and diagnosis window, otherwise, keeping the previous step;

(2-2) analyzing automatically feature points of the saved ECG, PCG and high frequency APG waveforms and displaying on the test result window if a systolic bio-signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-3) analyzing automatically feature points of the saved ECG, PCG and low frequency APG waveforms and displaying on the test result window if a diastolic bio-signals analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-4) displaying the saved left and right carotid artery waveforms on the test result window if a synthesized signal analysis command is received from the analysis menu window, otherwise, keeping the previous step;

(2-5) displaying enlarged waveforms analyzed in a selected interval on a lower left corner of the test result window if a detail analysis interval is selected in the left and right carotid artery waveforms showing on the test result window, otherwise, keeping the previous step; and

(2-6) displaying an aortic arch internal pressure curve, which is synthesized with the information including the saved ECG, PCG and APG waveforms, in a place clicked on the test results window if a vacant space of a lower right corner of the test results window is clicked after the sequential displays of the enlarged left and right carotid artery waveforms on the lower left corner of the test results window, otherwise, keeping the previous step.

70. The cardiovascular analyzer of claim 69,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.

71. The cardiovascular analyzer of claim 69,

wherein the steps 2-2 to 2-4 return to the step 1-1, respectively, if a test command is received from the result and diagnosis window after displaying each waveform on the test result window, otherwise, going to each next step.

72. The cardiovascular analyzer of claim 70,

wherein the result menu window comprises a C-R chart assessment;

wherein the C-R chart divides into sectors to show the coronary artery states according to the clinical results; and

wherein the result of the C-R chart assessment is dotted on the C-R chart to show the states of the left and right coronary arteries of an examinee.

28-1. The cardiovascular analyzer of claim 27,

wherein the step 3 comprises:

(3-1) displaying a result menu window and a output device if a result display command is received from the test and diagnosis window, otherwise, keeping the previous step;

(3-2) displaying a selected menu result if one is selected on the result menu window, otherwise, keeping the previous step; and

(3-3) outputting the selected menu result if an output command is received from the output device after displaying the selected menu result, otherwise, keeping the previous step.