Bladder Arrangement For Microneedle-Based Drug Delivery Device
First Claim
1. A bladder arrangement for an active transdermal drug delivery device, comprising:
- a first flexible membrane having an inner and outer surface;
a bladder member including an inner surface and an outer surface, the inner surface of the flexible membrane and the inner surface of the bladder member defining a chamber for receiving a drug therein;
an array of microneedles, each microneedle having an input;
a valve arrangement communicating with the inputs of the microneedles through a passageway and being operatively connected to the rigid bladder member, the valve arrangement movable between a first configuration wherein the inputs of the microneedles are is isolated from the drug in the chamber and a second configuration wherein the passageway communicates with the drug in the chamber;
wherein the bladder member has greater rigidity than the flexible membrane.
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Accused Products
Abstract
A bladder arrangement is provided for a microneedle-based drug delivery device. The bladder arrangement includes a flexible membrane having an inner surface, an outer surface and an outer periphery. A bladder member, having a rigidity greater than the flexible membrane, includes an inner surface, an outer surface and an outer periphery. The inner surface of the flexible membrane and the inner surface of the bladder member define a chamber for receiving a drug therein. At least one microneedle is operatively connected to the bladder member. The at least one microneedle has an input and an output receivable within the individual. A valve operatively connects the input of the at least one microneedle and the chamber.
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Citations
20 Claims
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1. A bladder arrangement for an active transdermal drug delivery device, comprising:
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a first flexible membrane having an inner and outer surface; a bladder member including an inner surface and an outer surface, the inner surface of the flexible membrane and the inner surface of the bladder member defining a chamber for receiving a drug therein; an array of microneedles, each microneedle having an input; a valve arrangement communicating with the inputs of the microneedles through a passageway and being operatively connected to the rigid bladder member, the valve arrangement movable between a first configuration wherein the inputs of the microneedles are is isolated from the drug in the chamber and a second configuration wherein the passageway communicates with the drug in the chamber; wherein the bladder member has greater rigidity than the flexible membrane. - View Dependent Claims (2, 4, 5, 6)
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3. (canceled)
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7. A bladder arrangement for a drug delivery device, comprising:
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a flexible membrane having an inner surface, an outer surface and an outer periphery; a bladder member including an inner surface, an outer surface and an outer periphery bonded to the outer periphery of the flexible membrane, the inner surface of the flexible membrane and the inner surface of the bladder member defining a chamber for receiving a drug therein; an array of microneedles, each microneedle having an input communicating with a passageway; and a valve arrangement for controlling the flow of the drug from the chamber to the passageway; wherein the bladder member is more rigid than the flexible member. - View Dependent Claims (8, 10, 11, 12, 13)
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9. (canceled)
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14. A bladder arrangement for a drug delivery device, comprising:
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a flexible membrane having an inner surface, an outer surface and an outer periphery; a bladder member being more rigid than the flexible membrane and including an inner surface, an outer surface and an outer periphery, the inner surfaces of the flexible membrane and the inner surface of the bladder member defining a chamber for receiving a drug therein; an array of microneedles having inputs communicating with a passageway and outputs receivable within the individual; and a valve operatively connecting passageway and the chamber. - View Dependent Claims (15, 16, 18, 19, 20)
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17. (canceled)
Specification