DRUG DELIVERY DEVICE INCLUDING MULTI-FUNCTIONAL COVER

• US 20110172638A1
• Filed: 01/08/2010
• Published: 07/14/2011
• Est. Priority Date: 01/08/2010
• Status: Abandoned Application

• Current Assignee: FluGen, Inc., Ratio, Inc.
• Original Assignee: FluGen, Inc., Ratio, Inc.
• Inventors: Smith, Garrick D.S., Moga, Benjamin J., Chase, Kent
• Application Number:
  US12/684,840
• Publication Number:
  US 20110172638A1
• Time in Patent Office: Days
• US Class Current: 604/506
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14586 pressurised by means of a flexible diaphragm
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure

Abstract

An apparatus for delivering a drug to a subject is provided. The apparatus includes a housing, a microneedle coupled to the housing and configured to extend from the housing when activated, an activation control coupled to the housing and an outer shell. The outer shell includes a top wall having an inner surface and a sidewall extending from the top wall, the sidewall having an inner surface. The outer shell includes a first attachment structure configured to attach to the housing. The outer shell covers the activation control when the first attachment structure is attached to the housing. The outer shell includes a second attachment structure configured to attach to the housing. The outer shell covers the activated microneedle when the second attachment structure is attached to the housing.

Claims

1. An apparatus for delivering a drug to a subject, comprising:

a housing;

a microneedle coupled to the housing and configured to extend from the housing when activated;

an activation control coupled to the housing; and

an outer shell comprising;

a top wall having an inner surface;

a sidewall extending from the top wall, the sidewall having an inner surface;

a first attachment structure configured to attach to the housing, wherein the outer shell covers the activation control when the first attachment structure is attached to the housing; and

a second attachment structure configured to attach to the housing, wherein the outer shell covers the activated microneedle when the second attachment structure is attached to the housing.

2. The apparatus of claim 1, wherein the inner surface of the top wall and the inner surface of the sidewall define a central chamber.

3. The apparatus of claim 2, wherein the activation control and the housing are received within the central chamber when the first attachment structure is attached to the housing.

4. The apparatus of claim 2, wherein the activated microneedle is received within the central chamber of the outer shell when the second attachment structure is attached to the housing.

5. The apparatus of claim 1, wherein the first attachment structure includes a tab extending from the inner surface of the sidewall, the tab having an inner surface, the inner surface of the tab engaging the housing to attach the outer shell to the housing.

6. The apparatus of claim 5, wherein the outer shell is configured to be attached to the housing via an interference fit between the tab and the housing.

7. The apparatus of claim 5, wherein the second attachment structure includes a bead extending from the inner surface of the sidewall and a recess formed in the sidewall positioned adjacent to the bead, and further wherein a portion of the housing is received within the recess when the outer shell is attached to the housing via the second attachment structure.

8. The apparatus of claim 7, wherein the portion of the housing is a flange extending from a lower peripheral edge of the housing, and the bead engages the flange to resist movement of the housing relative to the outer shell when the second attachment structure is attached to the housing.

9. The apparatus of claim 7, wherein the tab is located on the sidewall between the recess and the top wall.

10. An apparatus for delivering drug to a subject, comprising:

a housing;

a microneedle configured to extend from the housing when activated; and

an activation control coupled to the housing; and

an outer shell coupled to the housing, comprising;

a top wall having an inner surface;

a sidewall extending from a peripheral edge of the top wall, the sidewall having an inner surface, the inner surfaces of the top wall and the sidewall defining a central chamber;

a first attachment structure coupled to the housing, wherein the housing and the activation control are located within the central chamber when the outer shell is coupled to the housing via the first attachment structure; and

a second attachment structure configured to be coupled to the housing, wherein the activated microneedle is located within the central chamber when the outer shell is coupled to the housing via the second attachment structure.

11. The apparatus of claim 10, wherein the outer shell provides a sharp-safe container for disposing of the microneedle after the drug has been delivered.

12. The apparatus of claim 11, wherein the outer shell is made from a rigid material.

13. The apparatus of claim 10, wherein the housing includes a bottom wall having a lower surface, wherein the lower surface of the housing faces generally toward the top wall of the outer shell when the outer shell is coupled to the housing via the second attachment structure, and further wherein the lower surface of the housing faces generally away from the top wall of the outer shell when the outer shell is coupled to the housing via the first attachment structure.

14. The apparatus of claim 10, wherein the outer shell is coupled to the housing via the first attachment structure prior to activation, and further wherein the outer shell is coupled to the housing via the second attachment structure following drug delivery to facilitate disposal of the microneedle.

15. A method of delivering a drug to the skin of a subject, the method comprising:

providing a microneedle drug delivery device held within a protective cover;

attaching the microneedle drug delivery device to the skin of the subject via an attachment element;

removing the protective cover from the microneedle drug delivery device while the microneedle drug delivery device is attached to the skin of the subject to expose an activation control;

actuating the activation control to trigger insertion of a microneedle into the skin of the subject and to initiate drug delivery via the microneedle;

removing the microneedle drug delivery device from the skin of the subject; and

attaching the microneedle drug delivery device to the protective cover for disposal such that the exposed microneedle is covered by the protective cover.

16. The method of claim 15, wherein the protective cover includes a plurality of tabs configured to be coupled to an outer surface of the microneedle drug delivery device to hold the microneedle drug delivery device within the protective cover.

17. The method of claim 16, wherein the protective cover includes a recess that receives a portion of the microneedle drug delivery device to attach the protective cover to the microneedle drug delivery device.

18. The method of claim 15, wherein the removing the protective cover step includes applying an inwardly directed force to a sidewall of the protective cover.

19. The method of claim 15, further comprising the step of placing the protective cover onto a surface such that a top wall of the protective cover is in contact with the surface.

20. The method of claim 19, wherein the microneedle drug delivery device includes a bottom wall having a lower surface, wherein the lower surface of the bottom wall faces the top wall of the protective cover when the used microneedle drug delivery device is attached to the protective cover.