Device including altered microorganisms, and methods and systems of use
First Claim
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1. A computer-implemented method comprising:
- executing one or more instructions located on a recordable medium for regulating dispensing of at least one treatment device including at least one semi-permeable barrier substantially enclosing at least one auxotrophic microorganism, the at least one auxotrophic microorganism including at least one nucleic acid construct encoding at least one therapeutic agent, the barrier defining an interior region and exterior region;
wherein the device includes at least one metabolite required by the at least one auxotrophic microorganism.
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Abstract
Devices, methods, and systems are described for administration to at least one biological tissue of at least one device including at least one altered microorganism. In an embodiment, the altered microorganism includes at least one nucleic acid construct encoding at least one therapeutic agent.
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Citations
44 Claims
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1. A computer-implemented method comprising:
executing one or more instructions located on a recordable medium for regulating dispensing of at least one treatment device including at least one semi-permeable barrier substantially enclosing at least one auxotrophic microorganism, the at least one auxotrophic microorganism including at least one nucleic acid construct encoding at least one therapeutic agent, the barrier defining an interior region and exterior region;
wherein the device includes at least one metabolite required by the at least one auxotrophic microorganism.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. A computer program product, comprising:
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a recordable medium bearing one or more instructions for regulating dispensing of at least one treatment device including an semi-permeable barrier structured to substantially enclose at least one auxotrophic microorganism, and wherein the at least one auxotrophic microorganism includes at least one nucleic acid construct encoding at least one therapeutic agent. - View Dependent Claims (24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44)
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Specification