Microwell Sampling Tape Sealing Apparatus and Methods

• US 20110174435A1
• Filed: 10/01/2009
• Published: 07/21/2011
• Est. Priority Date: 10/02/2008
• Status: Abandoned Application

• Current Assignee: Douglas Scientific LLC
• Original Assignee: Douglas Scientific LLC
• Inventors: Peterson, Bruce Malcolm
• Application Number:
  US13/121,439
• Publication Number:
  US 20110174435A1
• Time in Patent Office: Days
• US Class Current: 156/292
• CPC Class Codes: B01L 2200/0689 Sealing
• CPC Class Codes: B01L 2200/12 Specific details about manufacturing devices
• CPC Class Codes: B01L 2300/044 pierceable, e.g. films, membranes
• CPC Class Codes: B01L 2300/0829 Multi-well plates; Microtitration plates
• CPC Class Codes: B01L 3/50853 with covers or lids
• CPC Class Codes: B29C 65/18 using heated tools
• CPC Class Codes: B29C 65/7841 Holding or clamping means for handling purposes clamping means for the purpose of applying pressure on the parts to be joined, in the area to be joined B29C66/81; work holders in general B25B; devices for holding or positioning work for welding metal B23K37/04
• CPC Class Codes: B29C 66/112 Single lapped joints
• CPC Class Codes: B29C 66/131 Single flanged joints, i.e. one of the parts to be joined being rigid and flanged in the joint area
• CPC Class Codes: B29C 66/438 Joining sheets for making hollow-walled, channelled structures or multi-tubular articles
• CPC Class Codes: B29C 66/53461 joining substantially flat covers and/or substantially flat bottoms to open ends of container bodies
• CPC Class Codes: B29C 66/81433 being toothed, i.e. comprising several teeth or pins comprising a single tooth B29C66/81429, or being patterned
• CPC Class Codes: B29C 66/81812 the welding jaws being cooled from the outside, e.g. by blowing a gas or spraying a liquid
• CPC Class Codes: B29C 66/83411 Roller, cylinder or drum types B29C66/83431 takes precedence; rollers, cylinders or drums moving relative to and tangentially to the parts to be joined B29C66/8362
• CPC Class Codes: B29C 66/83413 cooperating rollers, cylinders or drums
• CPC Class Codes: B29C 66/83417 said rollers, cylinders or drums being hollow
• CPC Class Codes: B29C 66/83511 jaws mounted on rollers, cylinders or drums
• CPC Class Codes: B29L 2031/7164 Blister packages
• CPC Class Codes: G01N 35/00009 provided with a sample supporting tape, e.g. with absorbent zones

Abstract

A sealing station (10) includes a shell (100) having holes (106) extending between inner and outer peripheries (102, 104) and arranged in a pattern to receive wells (30) of a carrier tape (20) directed on a portion of the outer periphery (104). Spaced, raised surfaces (150) are formed on the outer periphery (104) concentrically around and corresponding to the plurality of holes (106). A press roller (130) sandwiches a seal tape (60) against the carrier tape (20) in turn sandwiched against the spaced, raised surfaces (150) of the outer periphery (104) of the shell (100) to bond the seal tape (60) to the carrier tape (20) at areas corresponding to the spaced, raised surfaces (150).

Claims

1. Method of sealing comprising:

moving a shell having annular cross sections and including inner and outer peripheries, with a plurality of holes extending through the shell between the inner and outer peripheries, with the plurality of holes being in a pattern;

directing a carrier tape over a portion of the outer periphery of the moving shell, with the carrier tape including a plurality of wells corresponding to and received in the pattern of the plurality of holes of the shell; and

sandwiching a seal tape against the carrier tape in turn sandwiched against the outer periphery of the moving shell.

2. The method of claim 1 wherein moving the shell comprises moving the shell having a plurality of spaced, raised surfaces on the outer periphery around and corresponding to the plurality of holes, with sandwiching the seal tape comprising sandwiching the carrier tape against the plurality of spaced, raised surfaces, with the method further comprising:

bonding the seal tape to the carrier tape exclusively corresponding to the plurality of spaced, raised surfaces.

3. The method of claim 2 wherein moving the shell comprises moving the shell with the plurality of spaced, raised surfaces in the pattern of the holes and spaced from each other.

4. The method of claim 1 further comprising:

moving air into the inner periphery of the moving shell.

5. The method of claim 4 wherein moving the shell comprises moving the shell having inner and outer ends, with the inner and outer peripheries extending between the inner and outer ends, with the outer end being open, with moving air comprising moving air into the outer open end of the moving shell.

6. The method of claim 5 wherein moving the shell comprises moving the shell with the inner and outer peripheries being of concentric circular cross sections.

7. The method of claim 6 wherein moving the shell comprises rotating a shaft extending along an axial center of the concentric circular cross sections and secured to the shell.

8. The method of claim 7 wherein rotating the shaft comprises rotating the shaft connected to the shell at the inner end to cantilever support the shell.

9. The method of claim 1 wherein directing the carrier tape comprises tractor driving a plurality of sprocket drive holes along each edge of the carrier tape.

10. The method of claim 1 wherein sandwiching the seal tape comprises rolling a press roller on the seal tape opposite to the portion of the outer periphery of the moving shell.

11. Apparatus for sealing samples inside wells arranged in patterns in a carrier tape with a seal tape, comprising an anvil including an outer periphery, with a plurality of holes extending in the anvil from the outer periphery, with the plurality of holes being in the pattern of the wells in the carrier tape, a mechanism directing the carrier tape over a portion of the outer periphery of the anvil with the wells of the carrier tape received in the plurality of holes, and a pressing mechanism sandwiching the seal tape against the carrier tape in turn sandwiched against the outer periphery of the anvil;

with the anvil being in the form of a shell having annular cross sections and including an inner periphery, with the plurality of holes extending through the shell between the inner and outer peripheries.

12. The apparatus of claim 11 wherein the shell further includes a plurality of spaced, raised surfaces on the outer periphery around and corresponding to the plurality of holes, with the pressing mechanism including a heater thermally bonding the seal tape to the carrier tape exclusively corresponding to the plurality of spaced, raised surfaces.

13. The apparatus of claim 12 wherein the plurality of spaced, raised surfaces are in the pattern of the holes and spaced from each other.

14. The apparatus of claim 11 further comprising, in combination:

an air circulator moving air within the inner periphery of the shell.

15. The apparatus of claim 14 wherein the shell has inner and outer ends, with the inner and outer peripheries extending between the inner and outer ends, with the outer end being open, with the air circulator introducing air through the open outer end of the shell.

16. The apparatus of claim 15 wherein the inner and outer peripheries have concentric circular cross sections.

17. The apparatus of claim 16 wherein the shell includes a shaft extending along an axial center of the concentric circular cross sections and secured to the inner periphery of the shell.

18. The apparatus of claim 17 wherein the shaft is connected to the shell at the inner end to cantilever support the shell.

19. The apparatus of claim 11 wherein the pressing mechanism comprises a press roller rolling relative to the outer periphery of the shell.

20. The apparatus of claim 11 wherein the mechanism comprises a tractor driver engaging a plurality of sprocket drive holes along each edge of the carrier tape.

21. Method of sealing comprising:

moving an outer periphery of an anvil, with a plurality of holes extending from the outer periphery and being in a pattern, with the anvil having a plurality of spaced, raised surfaces on the outer periphery around and corresponding to the plurality of holes;

directing a carrier tape over a portion of the outer periphery of the moving anvil, with the carrier tape including a plurality of wells corresponding to and received in the pattern of the plurality of holes of the moving anvil;

sandwiching a seal tape against the carrier tape in turn sandwiched against the plurality of spaced, raised surfaces of the outer periphery of the moving anvil.

22. The method of claim 21 wherein moving the outer periphery comprises moving the outer periphery with the plurality of spaced, raised surfaces in the pattern of the holes and spaced from each other, with the plurality of spaced, raised surfaces being annular and concentric with the wells.

23. The method of claim 21 wherein the anvil is a shell having annular cross sections and an inner periphery spaced inwardly from the outer periphery, with the inner and outer peripheries being equally spaced, with the inner and outer peripheries being circular, with the holes extending between the inner and outer peripheries.

24. Apparatus for sealing samples inside wells arranged in patterns in a carrier tape with a seal tape, comprising, in combination:

an anvil including an outer periphery, with a plurality of holes extending from the outer periphery and in the pattern of the wells in the carrier tape, with the anvil having a plurality of spaced, raised surfaces on the outer periphery around and corresponding to the plurality of holes;

a mechanism directing the carrier tape over a portion of the outer periphery of the anvil with the wells of the carrier tape received in the plurality of holes; and

a pressing mechanism sandwiching the seal tape against the carrier tape in turn sandwiched against the plurality of spaced, raised surfaces of the outer periphery of the moving anvil.

25. The apparatus of claim 24 wherein the plurality of spaced, raised surfaces in the pattern of the holes is spaced from each other, with the plurality of spaced, raised surfaces being annular and concentric with the wells.

26. The apparatus of claim 24 wherein the anvil is a shell having annular cross sections and an inner periphery spaced inwardly from the outer periphery, with the inner and outer peripheries being equally spaced, with the inner and outer peripheries being circular, with the holes extending between the inner and outer peripheries.