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Method for Treating and Diagnosing Hematologic Malignancies

  • US 20110177088A1
  • Filed: 08/14/2008
  • Published: 07/21/2011
  • Est. Priority Date: 08/17/2007
  • Status: Active Grant
First Claim
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1. A method for treating a hematologic malignancy, comprising the use of a ligand of PD1, wherein said ligand of PD1 is selected from the group consisting of PD-L1 or a fragment thereof which binds to PD1, PD-L2 or a fragment thereof which binds to PD1, and an anti-PD1 antibody or a fragment thereof which binds to PD1, and wherein the hematologic malignancy is selected from the group consisting of a chronic lymphocytic leukemia of B-cell origin, a small lymphocytic lymphoma of B-cell origin, a multiple myeloma, an acute B cell leukemia and a mantle cell lymphoma.

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