SYSTEMS AND METHODS FOR VOLUME REDUCTION

• US 20110178362A1
• Filed: 04/01/2011
• Published: 07/21/2011
• Est. Priority Date: 02/06/2006
• Status: Abandoned Application

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Edwards Lifesciences Corporation
• Inventors: EVANS, Michael A., WATANABE, Gwendolyn A.
• Application Number:
  US13/078,820
• Publication Number:
  US 20110178362A1
• Time in Patent Office: Days
• US Class Current: 600/16
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12099 characterised by the location of the occluder
• CPC Class Codes: A61B 17/12122 within the heart for closing a cardiac septal defect A61B17/0057
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12195 comprising a curable material
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/12054 Details concerning the detachment of the occluding device from the introduction device
• CPC Class Codes: A61F 5/0086 using clamps, folding means or the like
• CPC Class Codes: A61F 6/225 transcervical
• CPC Class Codes: A61M 29/02 Dilators made of swellable material balloon catheters for angioplasty A61M25/104

Abstract

Systems and methods are provided for reducing the effective volume of a cardiac ventricle. A ventricular volume reduction system may include a containment system or container body deliverable through a catheter into the ventricle, with the containment system or container body being fillable to occupy space within the ventricle. A ventricular volume reduction system may include a partition that sequesters a portion of the ventricle and separates it from the flow path of blood in the ventricle. Methods for reducing the effective ventricular chamber volume may include placement of the containment system, the container body or the partition within the ventricle.

Claims

1. A ventricular chamber volume reduction system, wherein the ventricular chamber has an apex and a wall, comprising:

a frame comprising an anchor radially extending from the frame;

a containment device deliverable through an intravascular catheter into a ventricular chamber and expandable from a collapsed shape to a filled shape once delivered into the ventricular chamber; and

a filler within the containment device, wherein the filler expands the containment device from the collapsed shape to the filled shape; and

wherein the containment device is configured to fit to the contour of the ventricular chamber wall extending from the apex of the ventricular chamber to the surface of the containment device farthest away from the apex, and wherein the containment device is configured to substantially fill the volume between the surface of the containment device farthest away from the apex and the apex.

2. The system of claim 1, further comprising a partition, wherein the partition is adjacent to the containment device, wherein the partition is positioned on the side of the containment device away from the apex.

3. The system of claim 2, wherein the partition is resilient.

4. The system of claim 1, wherein the containment device comprises a substantially conical configuration.

5. The system of claim 1, wherein the filler is curable.

6. The system of claim 1, wherein the filler comprises a polymer.

7. The system of claim 1, further comprising attachment mechanisms that affix the containment device to a wall of the ventricular chamber.

8. The system of claim 1, further comprising a fillport for the containment device.

9. The system of claim 1, wherein the containment device is configured so that the volume within the containment device is adjustable after the containment device is delivered to a target site.

10. A ventricular chamber volume reduction system, comprising:

a frame comprising an anchor extending radially from the frame;

a container body deliverable into a portion of a ventricular chamber, and wherein the container body is expandable from a first shape to a second shape when delivered into the ventricular chamber, the container body having a tissue surface in contact with a wall of the ventricular chamber and an exposed surface facing into the volume of the ventricular chamber not occupied by the container body, and wherein the exposed surface substantially spans across the ventricular chamber, wherein the container body comprises a fillport, and wherein the container body is attached to the frame,

wherein the second shape of the container body occupies substantially all of the space in the ventricular chamber between the wall of the portion of the ventricular chamber and the exposed surface, and wherein the second shape of the container body is in contact with the wall from the apex of the ventricular chamber to the surface of the container farthest away from the apex, thereby reducing ventricular volume exposed to a flow of blood.

11. The system of claim 10, further comprising a partition, wherein the partition is positioned on the side of the container adjacent to the exposed surface.

12. The system of claim 10, wherein the container body comprises an attachment device that affixes the tissue surface to the wall of the ventricular chamber.

13. The system of claim 10, wherein the containment body is configured so that the volume within the containment body is adjustable after the containment device is delivered to a target site.

14. The system of claim 10, wherein the second shape of the container body is configured to conform with the wall of the apex of the ventricular chamber.

15. A ventricular chamber volume reduction system, comprising:

a frame comprising an anchor extending radially from the frame;

a partition sequestering a portion of a ventricular chamber, thereby substantially removing the portion from a flow path for blood flowing within the ventricular chamber, the partition having an exposed surface facing the flow path, wherein placement of the partition decreases volume of blood flowing along the flow path within the ventricular chamber, and wherein the partition is resilient; and

a fillable container volume having a substantially open central port, the container volume configured to be positioned between the partition and the apex portion of the ventricular chamber, wherein the container is configured to contact the wall of the ventricular chamber from the apex extending to the terminal end of the container adjacent to the partition, and wherein the container is configured to allow the resilient movement of the partition within the central port.

16. The system of claim 15, wherein the partition is attached to the fillable container.

17. The system of claim 15, wherein the partition is configured to be attached to a tissue surface of the wall of the ventricular chamber.

18. The system of claim 15, wherein the partition comprises with an antithrombogenic material.

19. The system of claim 15, wherein the fillable container is configured so that the volume within the fillable container is adjustable after the fillable container is delivered to a target site.

20. The system of claim 15, wherein the fillable container is configured to conform with the wall of the apex of the ventricular chamber.