PATIENT FEEDBACK FOR CONTROL OF ULTRASOUND DEEP-BRAIN NEUROMODULATION
First Claim
1. A method of modulating a deep-brain targets using ultrasound neuromodulation, the method comprising:
- a mechanism for aiming one or a plurality of ultrasound transducers at one or more a deep-brain targets;
applying power to each of the ultrasound transducers via a control circuit thereby modulating the activity of the deep brain target region;
providing a mechanism for feedback from the patient based on the acute sensory or motor conditions of the patient; and
using that feedback to control one or more parameters to maximize the desired effect.
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Abstract
Disclosed are methods and systems and methods for patient-feedback control of non-invasive deep brain or superficial neuromodulation using sound impacting one or multiple points in a neural circuit to produce acute effects and, with application in multiple sessions, Long-Term Potentiation (LTP) or Long-Term Depression (LTD) to treat indications such as neurologic and psychiatric conditions. One or more of sonic transducer positioning, intensity, frequency, dynamic sweeps, phase/intensity relationships, and firing patterns are changed through feedback from the patient to optimize patient experience through up-regulation or down regulation. Examples are decreases in acute pain or tremor due to more effective impact on the neural targets.
110 Citations
20 Claims
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1. A method of modulating a deep-brain targets using ultrasound neuromodulation, the method comprising:
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a mechanism for aiming one or a plurality of ultrasound transducers at one or more a deep-brain targets; applying power to each of the ultrasound transducers via a control circuit thereby modulating the activity of the deep brain target region; providing a mechanism for feedback from the patient based on the acute sensory or motor conditions of the patient; and using that feedback to control one or more parameters to maximize the desired effect. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification