HANDHELD TRANSDERMAL DRUG DELIVERY AND ANALYTE EXTRACTION
4 Assignments
0 Petitions
Accused Products
Abstract
Apparatus (20) for application to skin of a subject is provided. The apparatus includes a board (30) having a first surface and a second surface, the first surface including a plurality of ablation electrodes (41), which are adapted to be applied to the skin, and the second surface including one or more contact pads (32), each one of the contact pads electrically coupled to at least one of the ablation electrodes. The apparatus further includes one or more driving electrodes (28). An energy applicator (e.g., motor 22), coupled to the driving electrodes, is adapted to pass the driving electrodes over the contact pads. A power source (e.g., power unit 102) is adapted to drive a current from the driving electrodes, to the contact pads, and to the ablation electrodes. The current is capable of ablating at least a portion of stratum corneum of the skin in a vicinity of the ablation electrodes, so as to facilitate transdermal transport of a substance.
108 Citations
134 Claims
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1-124. -124. (canceled)
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125. Apparatus for ablating stratum corneum, comprising:
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a housing; a set of two or more wires coupled to the housing, each wire having two ends and an intermediate portion, the wires supported by the housing so as not to touch each other; and a coupling element, electrically coupled to the intermediate portion of each of the wires, so that all of the ends of the wires substantially form a plane, the ends configured to function as electrodes for ablating stratum corneum of skin of a subject when applied to the skin. - View Dependent Claims (126, 127, 128, 129, 130, 131, 132, 133, 134)
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Specification