REGULATORY T CELL EPITOPES, COMPOSITIONS AND USES THEREOF
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Abstract
The invention is directed to T cell epitopes wherein said epitopes comprises a peptide or polypeptide chain comprising at least a portion of an immunoglobulin constant or variable region. The invention also relates to methods of using and methods of making the epitopes of the invention.
8 Citations
30 Claims
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1-23. -23. (canceled)
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24. An isolated T-cell epitope polypeptide consisting of the sequence of SEQ ID NO:
- 4.
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25. A pharmaceutical composition comprising a T-cell epitope polypeptide consisting of the sequence of SEQ ID NO:
- 4 and a pharmaceutically acceptable carrier.
- View Dependent Claims (26, 27)
- 28. A kit for repressing an antigen-specific immune response in a subject, wherein the kit comprises a T-cell epitope polypeptide consisting of the sequence of SEQ ID NO:
Specification