SYSTEM AND METHOD TO ESTIMATE REGION OF TISSUE ACTIVATION
First Claim
1. A computer-implemented method for determining the volume of activation of neural tissue, comprising:
- having one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters;
receiving input data that includes values for the stimulation parameters and defining the input vector using the input data;
applying the input vector to the function and obtaining the parameters for the one or more parametric equations;
solving the parametric equation to calculate the volume of activation; and
displaying the calculated volume of activation on a display screen.
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Abstract
A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation.
123 Citations
20 Claims
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1. A computer-implemented method for determining the volume of activation of neural tissue, comprising:
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having one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters; receiving input data that includes values for the stimulation parameters and defining the input vector using the input data; applying the input vector to the function and obtaining the parameters for the one or more parametric equations; solving the parametric equation to calculate the volume of activation; and displaying the calculated volume of activation on a display screen. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A computer system that is programmed to perform steps that comprise:
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providing one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters; receiving input data that includes values for the stimulation parameters and defining the input vector using the input data; applying the input vector to the function and obtaining the parameters for the one or more parametric equations; and solving the parametric equation to calculate the volume of activation.
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13. A non-transitory computer-readable storage medium comprising instructions for:
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providing one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters; receiving input data that includes values for the stimulation parameters and defining the input vector using the input data; applying the input vector to the function and obtaining the parameters for the one or more parametric equations; and solving the parametric equation to calculate the volume of activation.
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14. A method for determining a function that outputs the parameters of one or more parametric equations that define a volume of activation, comprising:
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having an electric field model of an electrode and a neural tissue model; coupling the electric field model to the neural tissue model to obtain volumes of activation for multiple different sets of stimulation parameters and electrode configuration parameters; fitting a geometric shape to the volumes of activation, wherein the geometric shape is defined by one or more parametric equations; and using a computational training algorithm to design a function that correlates the different sets of stimulation parameters and electrode configuration parameters to the parameters for the one or more parametric equations that represent the geometric shapes that are fitted to the volumes of activation. - View Dependent Claims (15, 16, 17, 18)
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19. A computer-implemented method comprising:
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providing a volume of tissue activation (VTA) estimator that includes artificial intelligence trained to output parameters corresponding to an estimated volume of tissue activation (VTA) for a set of input parameters, the input parameters including stimulation parameters and configuration parameters relating to configuration of electrode contact configurations; and employing the VTA estimator to determine the estimated VTA for input parameters for which no simulations or clinical studies have been performed. - View Dependent Claims (20)
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Specification