Apparatus For Enhancing Scattered Light Detection By Re-Directing Scattered Light Outside The Angular Range Of Collection Optics Back To The Sample And Method Of Fabricating Same

• US 20110194183A1
• Filed: 02/04/2011
• Published: 08/11/2011
• Est. Priority Date: 02/05/2010
• Status: Abandoned Application

• Current Assignee: Redox Biomedical, Inc.
• Original Assignee: C8 MediSensors, Inc.
• Inventors: Lipson, Janyce, Hofmeister, Rudolf J., Hallstein, Sascha, Lipson, Jan, Ice, Donald A.
• Application Number:
  US13/021,004
• Publication Number:
  US 20110194183A1
• Time in Patent Office: Days
• US Class Current: 359/601
• CPC Class Codes: B24B 1/00 Processes of grinding or polishing; Use of auxiliary equipment in connection with such processes
• CPC Class Codes: B24B 11/00 Machines or devices designed for grinding spherical surfaces or parts of spherical surfaces on work; Accessories therefor specially designed for optical surfaces B24B13/00, for seat surfaces B24B15/00
• CPC Class Codes: B24B 13/015 of television picture tube viewing panels, headlight reflectors or the like
• CPC Class Codes: G02B 27/0018 with means for preventing ghost images anti-reflection coatings G02B1/11

Abstract

An apparatus comprising an optical window transmits both an excitation beam to a sample and scattered light from the sample which is within the angular range of the collection optics. Scattered light from the sample outside the angular range of the collection optics is re-directed back to the sample by reflection from one or more surfaces of the apparatus. As a result, the magnitude of scattered light collected is increased.

Claims

1. An optical window for re-directing scattered radiation, the optical window comprising:

a first surface in proximity to a sample, the first surface substantially transparent to radiation transmitted to and emitted from an emission point of the sample;

a second surface distal from the sample, the second surface reflecting radiation emitted from the emission point at a first angle with respect to a normal of the first surface, the first angle being outside an angular range of a collection optics; and

a third surface, adjacent to the first and second surfaces, the third surface reflecting the radiation reflected from the second surface at a second angle substantially normal to the third surface, wherein the radiation reflected from the third surface is transmitted to the second surface and is reflected from the second surface substantially back toward the emission point.

2. The optical window of claim 1 wherein the first surface is substantially planar.

3. The optical window of claim 1 wherein the first surface comprises an aperture.

4. The optical window of claim 3 wherein the aperture comprises a reflective material.

5. The optical window of claim 1 wherein the second surface is substantially planar.

6. The optical window of claim 1 wherein the second surface comprises an anti-reflection coating.

7. The optical window of claim 6 wherein the anti-reflection coating covers an area comprising the angular range of the collection optics.

8. The optical window of claim 1 wherein the second surface comprises a reflective coating covering an area outside the angular range of the collection optics.

9. The optical window of claim 1 wherein the third surface is substantially spherical.

10. The optical window of claim 9 wherein the third surface is substantially spherical about a point located along a line normal to the first surface through the emission point, wherein the point is located on an opposite side of the second surface from the sample, and wherein the point is located equidistant from the second surface as the sample is from the second surface.

11. The optical window of claim 1 wherein the third surface comprises a reflective coating.

12. The optical window of claim 1 wherein a first index of refraction of the optical window is greater than a second index of refraction of a medium in contact with the third surface.

13. The optical window of claim 1 wherein the first angle is sufficiently large to cause total internal reflection at the second surface.

14. The optical window of claim 1 wherein a first index of refraction of the optical window is sufficiently high so as to cause total internal reflection at the first angle at the second surface.

15. The optical window of claim 1 wherein a first index of refraction of the optical window substantially matches a third index of refraction of the sample.

16. The optical window of claim 1, wherein the optical window comprises sapphire.

17. The optical window of claim 1 wherein the first and third surfaces are substantially spherical about a point located along a line normal to the first surface through the emission point, wherein the point is located on an opposite side of the second surface from the sample, and wherein the point is located equidistant from the second surface as the sample is from the second surface.

18. The optical window of claim 1 wherein the third surface is substantially spherical about the emission point.

19. The optical window of claim 18 wherein the second surface is substantially planar in the angular range of a collection optics.

20. A method for fabricating an optical window for re-directing scattered radiation, the method comprising:

grinding a first surface of a sphere;

polishing the first surface such that the first surface is substantially transparent to radiation incident to and emitted from an emission point of a sample in proximity to the first surface;

grinding a second surface of the sphere;

polishing the second surface such that the second surface reflects radiation emitted from the emission point at a first angle with respect to a normal of the first surface, the first angle being outside an angular range of a collection optics; and

polishing a third surface of the sphere adjacent to the first and second surfaces such that the third surface reflects the radiation reflected from the second surface at a second angle substantially normal to the third surface, wherein the radiation reflected from the third surface is transmitted to the second surface and is reflected from the second surface substantially back toward the emission point.

21. An optical window for re-directing scattered radiation, the optical window comprising:

a first surface in proximity to a sample, the first surface substantially transparent to radiation transmitted to and emitted from an emission point of the sample; and

a second surface distal from the sample, the second surface reflecting radiation emitted from the emission point at a first angle with respect to a normal of the first surface, the first angle being outside an angular range of a collection optics, the second surface reflecting the radiation at a second angle substantially normal to the second surface, wherein the radiation is reflected substantially back toward the emission point, and wherein the second surface substantially spherical about the emission point.

22. The optical window of claim 21 wherein the second surface comprises an anti-reflection coating covering an area comprising the angular range of the collection optics.

23. The optical window of claim 21 wherein the second surface comprises a reflective coating covering an area outside the angular range of the collection optics.

24. The optical window of claim 21 wherein a first index of refraction of the optical window is greater than a second index of refraction of a medium in contact with the second surface.