DIRECT LUNG SENSOR SYSTEMS, METHODS, AND APPARATUSES
First Claim
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1. A device for assessing physiological parameters of a lung, comprising:
- a catheter comprising a proximal end and a distal end, the catheter being adapted to fit into a bronchoscope; and
at least one sensor disposed at the distal end of the catheter, the sensor capable of detecting one or more physiological parameters of a lung.
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Abstract
Devices, systems, and methods for diagnosing physiological parameters of the lungs and treating associated medical conditions are disclosed herein. In particular, certain embodiments permit detection of air flow in lung passageways, air leaks, gas concentration (in particular oxygen), and temperature measurements. Measurements obtained using the devices, systems, and methods disclosed herein may also be used to determine optimal treatment sites for medical conditions such as emphysema, COPD, or lung volume reduction.
85 Citations
23 Claims
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1. A device for assessing physiological parameters of a lung, comprising:
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a catheter comprising a proximal end and a distal end, the catheter being adapted to fit into a bronchoscope; and at least one sensor disposed at the distal end of the catheter, the sensor capable of detecting one or more physiological parameters of a lung. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method of treating emphysema, the method comprising:
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advancing a sensor to a first reference site located in a lung; measuring oxygen concentration from the first reference site during at least one patient breathing cycle; advancing the sensor to one or more lung segments located more distally than the first reference site and measuring oxygen concentration from the one or more lung segments during at least one patient breathing cycle; correlating the oxygen concentration measured at the one or more lung segments with the oxygen concentration measured at the reference site to determine lung segments with poor oxygen absorption; and placing one or more treatment devices in the lung segments identified to have poor oxygen absorption. - View Dependent Claims (11, 12, 13)
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14. A method of treating air leaks in a lung, the method comprising inserting a gas sensor into a chest tube inserted at least partially into a patient'"'"'s lung, and further comprising:
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isolating a distal lung passageway; pressurizing the isolated distal lung passageway with a gas; monitoring a gas concentration with the gas sensor; and if the gas concentration increases, occluding the distal lung passageway, or, if the gas concentration does not increase, repeating the procedure at a different distal lung passageway. - View Dependent Claims (15, 16)
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17. A method of detecting collateral ventilation in a lung, comprising:
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inserting an air flow sensor into a lung passageway; detecting air flow velocity using the air flow sensor in the lung passageway during inspiration; and
,detecting air flow velocity using the air flow sensor in the lung passageway during expiration, wherein if the air flow velocity detected during inspiration is greater than the air flow velocity detected during expiration, the passageway is determined to be feeding collateral passageways, and is treated. - View Dependent Claims (18)
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19. A method of treating an aerobic bacterial infection in a lung, comprising,
obtaining a reference oxygen depletion rate; -
advancing a catheter comprising an oxygen sensor and an occluding balloon to a lung segment suspected to be infected; occluding the lung segment suspected to be infected with the occluding balloon; measuring the oxygen depletion rate in the lung segment suspected to be infected; and
,initiating treatment if the oxygen depletion rate in the lung segment suspected to be infected is greater than an a reference oxygen depletion rate. - View Dependent Claims (20, 21, 22)
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23. A method of treating lung tumors in a patient breathing an oxygen-enriched gas mixture, comprising
advancing a catheter comprising an oxygen sensor to a lung tumor site; -
advancing a combustion-causing tumor treatment device to the lung tumor site; monitoring the oxygen concentration at the lung tumor site; and initiating treatment at the lung tumor site with the tumor treatment device while the oxygen concentration at the lung tumor site is below a predetermined value.
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Specification