TREATMENT MEDIUM DELIVERY DEVICE AND METHODS FOR DELIVERY OF SUCH TREATMENT MEDIUMS TO THE EYE USING SUCH A DELIVERY DEVICE

• US 20110202020A1
• Filed: 04/07/2011
• Published: 08/18/2011
• Est. Priority Date: 07/02/2004
• Status: Active Grant

• Current Assignee: Mati Therapeutics, Inc
• Original Assignee: QT Incorporated
• Inventors: LAZAR, Eliot
• Granted Patent: US 9,180,045 B2
• Time in Patent Office: Days
• US Class Current: 604/294
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00772 Apparatus for restoration of tear ducts

Abstract

A device for delivering a treatment medium to an eye includes a first body portion configured to be removably inserted and secured in an opening of the eye, and a second body portion supported by the first body portion. At least the second body portion includes a treatment medium, and a coating having an opening through which the treatment medium elutes out of the device.

Claims

1. A device for delivering a treatment medium to an eye, the device comprising:

a first body portion configured to be removably inserted and secured in an opening of the eye; and

a second body portion supported by the first body portion, at least the second body portion comprising a treatment medium, and a coating having an opening through which the treatment medium elutes out of the device.

2. The device according to claim 1, wherein the treatment medium comprises a prostaglandin.

3. The device according to claim 1, wherein the treatment medium comprises an agent selected from the group consisting of:

an antiallergenic agent, an antimicrobial agent, an anti-inflammatory agent, and an immunosuppressive agent.

4. The device according to claim 1, wherein the opening in the eye is a punctum, and wherein the first portion comprises a plug type member configured to be removably secured within the punctum.

5. The device according to claim 1, wherein the opening is configured to allow the treatment medium to elute through the opening in the coating to achieve near-order release kinetics.

6. A device for delivering a treatment medium to an eye, the device comprising:

a first body portion configured to be removably inserted in a punctum and secured in a canaliculus of the eye; and

a second body portion configured to rest upon an exterior surface of the punctum, at least the second body portion comprising a treatment medium, and a coating having an opening through which the treatment medium elutes out of the device.

7. The device according to claim 6, wherein the treatment medium comprises a prostaglandin.

8. The device according to claim 6, wherein the treatment medium comprises an agent selected from the group consisting of:

an antiallergenic agent, an antimicrobial agent, an anti-inflammatory agent, and an immunosuppressive agent.

9. The device according to claim 6, wherein the opening is configured to allow the treatment medium to elute through the opening in the coating to achieve near-order release kinetics.

10. A device for delivering a treatment medium to an eye, the device comprising:

a first body portion configured to be removably inserted and secured in an opening in the eye; and

a second body portion supported by the first body portion, at least the second body portion comprising a biodegradable polymer and a therapeutic medium.

11. The device according to claim 10, wherein the biodegradable polymer contains microparticles of the therapeutic medium.

12. The device according to claim 10, wherein the therapeutic medium is embedded within the biodegradable polymer.

13. The device according to claim 10, wherein the therapeutic medium comprises a prostaglandin.

14. The device according to claim 10, wherein the therapeutic medium comprises an agent selected from the group consisting of:

an antiallergenic agent, an antimicrobial agent, an anti-inflammatory agent, and an immunosuppressive agent.

15. The device according to claim 10, wherein the opening in the eye is a punctum, and wherein the first portion comprises a plug type member configured to be removably secured within the punctum.

16. A device for delivering a treatment medium to an eye, the device comprising:

a first body portion configured to be removably inserted and secured in an opening of the eye;

a second body portion supported by the first body portion;

a treatment medium;

a coating applied to at least the second body portion; and

an opening in the coating applied to the second body portion through which the treatment medium elutes out of the device.

17. The device according to claim 16, wherein the treatment medium comprises a prostaglandin.

18. The device according to claim 16, wherein the treatment medium comprises an agent selected from the group consisting of:

an antiallergenic agent, an antimicrobial agent, an anti-inflammatory agent, and an immunosuppressive agent.

19. The device according to claim 16, wherein the opening in the eye is a punctum, and wherein the first portion comprises a plug typo member configured to be removably secured within the punctum.

20. The device according to claim 16, wherein the opening is configured to allow the treatment medium to elute through the opening in the coating to achieve near-order release kinetics.