SYSTEM AND METHOD FOR DETECTING INTERMITTENT INTERRUPTIONS IN ELECTRICAL STIMULATION THERAPY OF A PATIENT

• US 20110202112A1
• Filed: 08/17/2010
• Published: 08/18/2011
• Est. Priority Date: 08/19/2009
• Status: Abandoned Application

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories Incorporated)
• Inventors: Ruais, Jonathan
• Application Number:
  US12/858,252
• Publication Number:
  US 20110202112A1
• Time in Patent Office: Days
• US Class Current: 607/60
• CPC Class Codes: A61B 2560/0271 using a remote monitoring unit
• CPC Class Codes: A61B 2560/0276 Determining malfunction
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61N 1/3605 Implantable neurostimulators for stimulating central or peripheral nerve system
• CPC Class Codes: A61N 1/37241 providing test stimulations
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

In one embodiment, a method of identifying a cause of intermittent interruption in stimulation therapy, comprises: communicating a signal by an external controller device to an implantable pulse generator to initiate a diagnostic mode; generating a stimulation pulses by the implantable pulse generator for application to tissue of the patient through one or more electrodes of a stimulation lead during the diagnostic mode; measuring impedance values for stimulation pulses applied to tissue of the patient through the stimulation lead during the diagnostic mode; directing the patient to perform one or more physical movements while the implantable pulse generator is operating in the diagnostic mode; processing the impedance values to identify time-domain limited variations in the impedance measurements from an expected value range; and displaying on the external controller device identification of one or more electrodes exhibiting intermittent electrical breaks or shorts in accordance with the processed impedance measurements.

Claims

1. A method of identifying a cause of intermittent interruption in stimulation therapy provided by a neurostimulation system implanted in a patient, the stimulation system comprising an implantable pulse generator and at least one stimulation lead, comprising:

communicating a signal by an external controller device to the implantable pulse generator to initiate a diagnostic mode;

generating a plurality of stimulation pulses by the implantable pulse generator for application to tissue of the patient through one or more electrodes of the stimulation lead during the diagnostic mode;

measuring impedance values for stimulation pulses applied to tissue of the patient through one or more electrodes of the stimulation lead during the diagnostic mode;

directing the patient to perform one or more physical movements while the implantable pulse generator is operating in the diagnostic mode;

processing the impedance values to identify time-domain limited variations in the impedance measurements from an expected value range; and

displaying on the external controller device identification of one or more electrodes exhibiting intermittent electrical breaks or shorts in accordance with the processed impedance measurements.

2. The method of claim 1 wherein the processing comprises:

identifying impedance values exceeding an impedance limit value.

3. The method of claim 1 wherein the processing comprises:

identifying impedance values falling below a minimum impedance value.

4. The method of claim 1 wherein the processing comprises:

identifying abrupt changes in impedance values over a time-period of less than one second.

5. The method of claim 1 further comprising:

communicating impedance values from the implantable pulse generator to the external controller, wherein the processing of the impedance values is performed by software code executed by a processor of the external controller device.

6. The method of claim 1 further comprising:

communicating a second signal from the external controller to the implantable pulse generator to cause the implantable pulse generator to exit the diagnostic mode.

7. The method of claim 1 wherein the generating comprises:

applying stimulation pulses through outputs of the implantable pulse generator according stimulation parameters defined by one or more patient therapy programs.

8. The method of claim 1 wherein generating comprises:

applying stimulation pulses through outputs of the implantable pulse generator by rotating stimulation pulses through each output of the implantable pulse generator.

9. The method of claim 1 wherein the generating comprises:

applying stimulation pulses at amplitudes below perception threshold for the patient.

10. The method of claim 1 further comprising:

displaying a range of impedance values by the external controller for each electrode used to apply stimulation to tissue of the patient during the diagnostic mode.

11. A neurostimulation system, comprising:

an implantable pulse generator for generating stimulation pulses;

at least one implantable stimulation lead for applying stimulation pulses to tissue of a patient; and

an external controller for controlling operations of the implantable pulse generator, the external controller comprising a processor and memory storing software code, the software code comprising;

(i) first code for communicating a signal to the implantable pulse generator to cause the implantable pulse generator to enter a diagnostic mode, wherein the pulse generator generates a plurality of stimulation pulses for application to tissue of the patient through one or more electrodes of the stimulation lead and measures impedance values for stimulation pulses applied through the one or more electrodes during the diagnostic mode;

(ii) second code for receiving impedance data from the diagnostic mode from the implantable pulse generator;

(iii) third code for processing the impedance data to identify time-domain limited variations in the impedance data from an expected value range; and

(iv) fourth code for displaying identification of one or more electrodes exhibiting intermittent electrical breaks or shorts in accordance with the processed impedance measurements.

12. The system of claim 11 wherein the third code is operable to identify values in the impedance data exceeding an impedance limit value.

13. The system of claim 11 wherein the third code is operable to identify values in the impedance data falling below a minimum impedance value.

14. The system of claim 11 wherein the third code is further operable to identify abrupt changes in values in the impedance data over a time-period of less than one second.

15. The system of claim 11 wherein the implantable pulse generator, during the diagnostic mode, is operable to apply stimulation pulses through outputs of the implantable pulse generator according stimulation parameters defined by one or more patient therapy programs.

16. The system of claim 11 wherein the implantable pulse generator, during the diagnostic mode, is operable to apply stimulation pulses through outputs of the implantable pulse generator by rotating stimulation pulses through each output of the implantable pulse generator.

17. The system of claim 11 wherein the implantable pulse generator, during the diagnostic mode, is operable to apply stimulation pulses through outputs of the implantable pulse generator at amplitudes below stimulation threshold values for the patient.

18. The system of claim 11 wherein the fourth code is further operable to display a range of measured impedance values by the external controller for each electrode used to apply stimulation to tissue of the patient during the diagnostic mode.