Method and apparatus for detecting the respiratory activity of a person

• US 20110208082A1
• Filed: 03/23/2011
• Published: 08/25/2011
• Est. Priority Date: 06/30/2000
• Status: Active Grant

• Current Assignee: ResMed Humidification Technologies GmbH (ResMed Incorporated)
• Original Assignee: MAP Medizin-Technologie GMBH (ResMed Incorporated)
• Inventors: Jakobs, Rainer, Schneider, Hartmut, Vogele, Harald, Madaus, Stefan
• Granted Patent: US 8,408,205 B2
• Time in Patent Office: Days
• US Class Current: 600/538
• CPC Class Codes: A61M 16/0051 with alarm devices
• CPC Class Codes: A61M 16/026 specially adapted for predicting, e.g. for determining an information representative of a flow limitation during a ventilation cycle by using a root square technique or a regression analysis
• CPC Class Codes: A61M 2016/0021 with a proportional output signal, e.g. from a thermistor
• CPC Class Codes: A61M 2016/0039 in the inspiratory circuit

Abstract

A method and a device are provided for detecting the respiratory activity of a person and for controlling the time progression of breathing gas pressure, especially in accordance with physical parameters and considering parameters indicating the momentary physiological condition of the breathing person. The device for detecting the respiratory activity of a person has at least one sensor that provides a first signal indicating the breathing gas flow, wherein at least one signal processing device is provided for processing the first signal. The signal processing device is configured in such a way that said device determines a reference-relation on the basis of the first signal detected during a first time interval. On the basis thereof, the device determines a correlation-relation between the reference-relation and the first signal. The device generates an output signal indicating the respiratory activity and/or the physiological condition of the breathing person by considering at least the correlation-relation.

Claims

1-23. -23. (canceled)

24. A device for detecting a person'"'"'s breathing activity and/or physiological condition, comprising:

a flow sensor configured to generate a first signal indicative of breathing gas flow over at least two breathing cycles; and

at least one processor configured to;

designate a limited portion of the first signal as a reference signal,

compare the reference signal with at least a portion of the first signal, and

generate, based on the comparison, an output signal indicative of the breathing activity and/or the physiological condition of the person.

25. The device of claim 24, wherein the at least one processor is configured to mathematically correlate the reference signal with the first signal as the comparison.

26. The device of claim 25, wherein the mathematically correlation results in values between −

1 and 1.

27. The device of claim 26, wherein the at least one processor is further configured to determine whether successive breathing cycles are similar by determining whether a graph of the mathematical correlation in corresponding portions has a similar periodicity, and whether in the corresponding portions local maxima are close to 1 and local minima are close to −

1.

28. The device of claim 26, wherein the at least one processor is further configured to recognize whether the person'"'"'s respiration is regular.

29. The device of claim 26, wherein the at least one processor is further configured to recognize whether the person'"'"'s breaths are missed completely.

30. The device of claim 24, wherein the at least one processor is further configured to:

generate a signal corresponding to the first derivative of the first signal, identify local maxima and minima of the signal corresponding to the first derivative of the first signal,

recognize transitions between inspiration and expiration with reference to the local maxima and minima, and

distinguish between individual breathing phases in accordance with the recognized transitions.

31. The device of claim 24, wherein the at least one processor is further configured to cause a flow generator to adjust an amount of pressure provided to the person in dependence on the output signal.

32. The device of claim 24, wherein the first signal extends over at least three breathing cycles, and wherein the reference signal corresponds to two breathing cycles.

33. The device of claim 32, wherein the reference signal corresponds to at least two breathing cycles.

34. The device of claim 24, further comprising a filter configured to alter the first signal by removing or suppressing a predetermined frequency range therein.

35. The device of claim 24, wherein the at least one processor is further configured to smooth the reference signal in accordance with smoothing criteria.

36. The device of claim 35, wherein the smoothing criteria are adaptively changeable based on a detected breathing state.

37. The device of claim 35, wherein the smoothing criteria are selected from preset smoothing criteria for respective respiratory states.

38. The device of claim 24, wherein the portion of the first signal to which the reference signal is compared occurs prior to a time at which the reference signal is designated.

39. The device of claim 24, wherein the at least one processor is further configured to compare the reference signal with at least a portion of the first signal received after the reference signal has been designated.

40. A device for detecting a person'"'"'s breathing activity and/or physiological condition, comprising:

a flow sensor configured to generate a first signal indicative of breathing gas flow over at least two breathing cycles; and

at least one processor configured to;

monitor a second signal indicative of an amount of pressure provided to the person via a flow generator,

designate a limited portion of the first signal as a reference signal,

compare the reference signal with at least a portion of the first signal, and

generate, based on the comparison, an output signal indicative of the breathing activity and/or the physiological condition of the person.

41. The device of claim 40, wherein the at least one processor is configured to mathematically correlate the reference signal with the first signal as the comparison.

42. The device of claim 41, wherein the mathematically correlation results in values between −

1 and 1.

43. The device of claim 40, wherein the at least one processor is further configured to cause the flow generator to adjust the amount of pressure provided to the person in dependence on the output signal.

44. The device of claim 40, further comprising a filter configured to alter the first signal by removing or suppressing a predetermined frequency range therein.

45. The device of claim 40, further comprising a filter configured to alter the second signal by removing or suppressing a predetermined frequency range therein.

46. The device of claim 40, further comprising a filter configured to alter the first and second signals by removing or suppressing a predetermined frequency range therein.

47. The device of claim 40, wherein the at least one processor is further configured to identify snoring by detecting a increase in a variance of the second signal in one or more breathing cycles.

48. The device of claim 41, wherein the at least one processor is further configured to identify mouth breathing by detecting a negative correlation.

49. The device of claim 41, wherein the at least one processor is further configured to identify obstructive apneas by detecting a weakened and/or missing peak of correlation.

50. The device of claim 40, wherein the at least one processor is further configured to identify flow limited breathing by determining whether a maximum inspiration flow occurs within the first half of an inspiration cycle.

51. A method for detecting a person'"'"'s breathing activity and/or physiological condition, comprising:

generating a first signal indicative of breathing gas flow over at least two breathing cycles;

designating a limited portion of the first signal as a reference signal;

comparing the reference signal with at least a portion of the first signal; and

generating, based on the comparison, an output signal indicative of the breathing activity and/or the physiological condition of the person.

52. The method of claim 51, wherein the comparing comprises mathematically correlating the reference signal with the first signal.

53. The method of claim 52, wherein the mathematically correlation results in values between −

1 and 1.

54. The method of claim 53, further comprising determining whether a graph of the mathematical correlation in corresponding portions has a similar periodicity, and whether in the corresponding portions local maxima are close to 1 and local minima are close to −

1, in order to determine whether successive breathing cycles are similar.

55. The method of claim 53, further comprising recognizing whether the person'"'"'s respiration is regular.

56. The method of claim 53, further comprising recognizing whether the person'"'"'s breaths are missed completely.

57. The device of claim 51, further comprising:

generating a signal corresponding to the first derivative of the first signal;

identifying local maxima and minima of the signal corresponding to the first derivative of the first signal;

recognizing transitions between inspiration and expiration with reference to the local maxima and minima; and

distinguishing between individual breathing phases in accordance with the recognized transitions.

58. The method of claim 51, further comprising causing a flow generator to adjust an amount of pressure provided to the person in dependence on the output signal.

59. The method of claim 51, wherein the first signal extends over at least three breathing cycles, and wherein the reference signal corresponds to two breathing cycles.

60. The method of claim 59, wherein the reference signal corresponds to at least two breathing cycles.

61. The method of claim 51, further comprising removing or suppressing a predetermined frequency range in the first signal.

62. The method of claim 51, further comprising smoothing the reference signal in accordance with smoothing criteria.

63. The method of claim 61, further comprising adaptively changing the smoothing criteria based on a detected breathing state.

64. The method of claim 62, wherein the smoothing criteria are selected from preset smoothing criteria for respective respiratory states.

65. The method of claim 51, wherein the portion of the first signal to which the reference signal is compared occurs prior to a time at which the reference signal is designated.

66. The method of claim 51, wherein the comparing comprises comparing the reference signal with at least a portion of the first signal received after the reference signal has been designated.

67. A method for detecting a person'"'"'s breathing activity and/or physiological condition, the method comprising:

generating a first signal indicative of breathing gas flow over at least two breathing cycles;

monitoring a second signal indicative of an amount of pressure provided to the person via a flow generator;

designating a limited portion of the first signal as a reference signal;

comparing the reference signal with at least a portion of the first signal; and

generating, based on the comparison, an output signal indicative of the breathing activity and/or the physiological condition of the person.

68. The method of claim 67, wherein the mathematically comparing comprises mathematically correlating the reference signal with the first signal.

69. The method of claim 67, wherein the mathematically correlation results in values between −

1 and 1.

70. The method of claim 67, further comprising causing the flow generator to adjust the amount of pressure provided to the person in dependence on the output signal.

71. The method of claim 67, further comprising filtering the first signal by removing or suppressing a predetermined frequency range therein.

72. The method of claim 67, further comprising filtering the second signal by removing or suppressing a predetermined frequency range therein.

73. The method of claim 67, further comprising filtering the first and second signals by removing or suppressing a predetermined frequency range therein.

74. The method of claim 67, further comprising identifying snoring by detecting a increase in a variance of the second signal in one or more breathing cycles.

75. The method of claim 67, further comprising identifying mouth breathing by detecting a negative correlation.

76. The method of claim 68, further comprising identifying obstructive apneas by detecting a weakened and/or missing peak of correlation.

77. The method of claim 67, further comprising identifying flow limited breathing by determining whether a maximum inspiration flow occurs within the first half of an inspiration cycle.