METHOD AND APPARATUS FOR OBJECTIVE ELECTROPHYSIOLOGICAL ASSESSMENT OF VISUAL FUNCTION
First Claim
1. An apparatusus for analysing at least one multifocal visual evoked potential response of at least two subjects, the at least one visual evoked potential response being induced by any mode of multifocal stimulation, wherein the stimulation mode is adapted to simultaneously stimulate different parts of the visual field of an eye of the subject such that different parts of the visual field are stimulated with random sequences of different timing or character, the apparatus comprising:
- (a) electrodes placed on the scalp or in contact with the eye of each subject configured to simultaneously record (A) the at least one visual evoked potential responses from each of the different parts of the visual field of the eye and (B) the subject'"'"'s overall spontaneous brain activity levels; and
(b) a computer configured to;
(bi) identify, for each subject, the alpha rhythm component in the subject'"'"'s overall spontaneous brain activity levels,(bii) remove, for each subject, the alpha rhythm component from the subject'"'"'s overall spontaneous brain activity levels;
(biii) calculate, for each subject, a corresponding scaling factor, the scaling factor being derived from the subject'"'"'s overall spontaneous brain activity levels from which the component of alpha rhythm is identified and removed; and
(biv) scale, for each subject, each subject'"'"'s visual evoked potential response using said each subject'"'"'s scaling factor such that the variability of the visual evoked potential responses induced by the multifocal stimulation between the at least two subjects is minimised.
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Abstract
For electrophysiological assessment of visual function using a head mounted stereo display (e.g. virtual reality goggles) for displaying a stimulus which is used to generate a retinal or cortical response. In particular, a method for objective electrophysiological assessment of visual function of at least one eye of a subject includes presenting a visual stimulus to at least one eye of the subject, recording at least one of a retinal response and, a cortical response generated as a result of the presenting; analyzing said response and, as a result of said analyzing, forming a map of the visual function of the at least one eye of the subject 6. The invention also relates to as system for such electrophysiological assessment.
84 Citations
8 Claims
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1. An apparatusus for analysing at least one multifocal visual evoked potential response of at least two subjects, the at least one visual evoked potential response being induced by any mode of multifocal stimulation, wherein the stimulation mode is adapted to simultaneously stimulate different parts of the visual field of an eye of the subject such that different parts of the visual field are stimulated with random sequences of different timing or character, the apparatus comprising:
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(a) electrodes placed on the scalp or in contact with the eye of each subject configured to simultaneously record (A) the at least one visual evoked potential responses from each of the different parts of the visual field of the eye and (B) the subject'"'"'s overall spontaneous brain activity levels; and (b) a computer configured to; (bi) identify, for each subject, the alpha rhythm component in the subject'"'"'s overall spontaneous brain activity levels, (bii) remove, for each subject, the alpha rhythm component from the subject'"'"'s overall spontaneous brain activity levels; (biii) calculate, for each subject, a corresponding scaling factor, the scaling factor being derived from the subject'"'"'s overall spontaneous brain activity levels from which the component of alpha rhythm is identified and removed; and (biv) scale, for each subject, each subject'"'"'s visual evoked potential response using said each subject'"'"'s scaling factor such that the variability of the visual evoked potential responses induced by the multifocal stimulation between the at least two subjects is minimised. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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Specification