LOW-PROFILE HEART VALVE AND DELIVERY SYSTEM
First Claim
1. A prosthetic valve, comprising:
- a stent portion defining a lumen through said stent portion;
a valve portion comprising one or more leaflets; and
a flexible sleeve coupling the stent portion to the valve portion;
wherein the prosthetic valve is transformable from a delivery configuration in which at least a portion of the one or more leaflets is positioned outside the lumen of the stent portion, to an operating configuration in which at least a portion of the one or more leaflets is positioned within the lumen of the stent portion.
1 Assignment
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Accused Products
Abstract
Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.
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Citations
34 Claims
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1. A prosthetic valve, comprising:
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a stent portion defining a lumen through said stent portion; a valve portion comprising one or more leaflets; and a flexible sleeve coupling the stent portion to the valve portion; wherein the prosthetic valve is transformable from a delivery configuration in which at least a portion of the one or more leaflets is positioned outside the lumen of the stent portion, to an operating configuration in which at least a portion of the one or more leaflets is positioned within the lumen of the stent portion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A prosthetic valve, comprising:
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a radially collapsible and expandable frame; and a leaflet structure comprising a plurality of leaflets, a plurality of reinforcement elements, and a plurality of leaflet-supporting members; wherein the frame is coupled to the leaflet structure such that the leaflets are positioned at least substantially outside of the frame, and wherein a portion of each of the leaflets is positioned in a respective gap formed between a respective reinforcement element and a respective leaflet-supporting member. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A method of implanting a replacement heart valve, comprising:
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mounting the replacement heart valve onto a delivery system in a delivery configuration, the replacement heart valve comprising a stent portion, a valve portion, and a flexible sleeve coupled to the stent portion, wherein the stent portion comprises an outer surface and an inner surface defining a lumen, wherein the valve portion comprises a plurality of leaflets, and wherein in the delivery configuration at least a portion of the leaflets are positioned outside of the lumen defined by the stent portion; advancing the replacement heart valve to an implant position adjacent a heart valve annulus; transitioning the replacement valve from the delivery configuration to an operating configuration, wherein in the operating configuration at least a portion of the leaflets are positioned within the lumen defined by the stent portion; and radially expanding the replacement heart valve to cause the stent portion to engage the heart valve annulus, thereby anchoring the replacement heart valve in position within the heart valve annulus. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. A prosthetic heart valve system, comprising:
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a delivery apparatus comprising an expansion device and a delivery catheter on which the expansion device is mounted; and a radially-expandable replacement valve mounted in a radially compressed state on the delivery catheter, wherein the replacement valve comprises a valve portion and a stent portion separated from one another along an axial direction and coupled by at least one pair of sliding rails, the expansion device being configured to expand the replacement valve and to position at least part of the valve portion within a lumen of the stent portion.
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Specification