Implantable Sensor Element
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Accused Products
Abstract
The invention relates to a sensor element (110) for detecting at least one analyte in a body fluid or in a body tissue (130), particularly for determining at least one metabolite concentration in a body fluid. The sensor element (110) comprises an implantable, one-piece shaped body (112), which comprises a sensor end (114) and a coupling end (116). The shaped body (112) comprises, in the area of the sensor end (114), at least one sensor area (118), which comprises at least one sensor material (122). The sensor material (122) changes at least one optically measurable property in the presence of the analyte. The shaped body (112) also has at least one optically transparent coupling part (120), which is designed to transmit electromagnetic radiation in at least one spectral range between the sensor area (118) and the coupling end (116). In the sensor area (118), the shaped body (112) has at least one optically transparent matrix material (124), and the analyte can at least partially diffuse through the matrix material (124) to the sensor material (122). The sensor material (122) is embedded in the matrix material (124). The coupling part (120) is formed at least partially by the matrix material (124).
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Citations
44 Claims
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1-23. -23. (canceled)
- 24. Sensor element for detecting at least one analyte in a body fluid or in a body tissue, particularly for determining at least one metabolite concentration in a body fluid, wherein the sensor element comprises an implantable, one-piece shaped body, wherein the shaped body comprises a sensor end and a coupling end, wherein the shaped body comprises, in the area of the sensor end, at least one sensor area, wherein the sensor area comprises at least one sensor material which changes at least one optically measurable property in the presence of the analyte, wherein the shaped body also has at least one optically transparent coupling part, wherein the coupling part is designed to transmit electromagnetic radiation in at least one spectral range between the sensor area and the coupling end, wherein the shaped body has, in the sensor area, at least one optically transparent matrix material, wherein the analyte can at least partially diffuse through the matrix material to the sensor material, wherein the sensor material is embedded in the matrix material, wherein the coupling part has a length between 1 millimetre and 8 millimetres and is formed at least partially by the matrix material, wherein the sensor material is at least partially embedded in the matrix material in microcapsules, wherein the matrix material comprises at least one curable plastic, in particular a crosslinkable plastic.
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36. Method for manufacturing a sensor element for detecting at least one analyte in a body fluid or in a body tissue, the method comprising:
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introducing a first prepolymer liquid with at least one first curable prepolymer for producing an optically transparent coupling part into a cannula; introducing a second prepolymer liquid with at least one second curable prepolymer for producing a sensor area into the cannula; introducing at least one sensor material into the second prepolymer liquid, wherein the sensor material changes at least one optically measurable property in the presence of the analyte; and crosslinking the first prepolymer liquid and the second prepolymer liquid, such that a shaped body with a sensor end and a coupling end is obtained. - View Dependent Claims (37, 38, 39, 40, 41, 42, 43, 44)
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Specification