Albumin fibers and fabrics and methods of generating and using same
2 Assignments
0 Petitions
Accused Products
Abstract
Provided are method of generating a fiber from a globular protein such as albumin. Also provided are albumin fibers and fabrics and methods of using same for bonding a damaged tissue or for ex vivo or in vivo formation of a tissue.
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Citations
46 Claims
- 1. A fiber comprising more than 50% albumin.
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2-4. -4. (canceled)
- 5. A composition-of-matter comprising an albumin polymer.
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6. (canceled)
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8-11. -11. (canceled)
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12. A method of generating a fiber from a globular protein, comprising:
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(a) dissolving the globular protein into a solution, said solution comprising a reducing agent; and (b) evaporating said solution under conditions suitable for polymerization of the globular protein; thereby generating the fiber from the globular protein. - View Dependent Claims (13, 14, 16, 17, 18, 24, 26, 27, 28, 30, 33, 36, 37, 41, 42)
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15. (canceled)
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19. A method of generating a fiber from a globular protein, comprising:
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(a) dissolving the globular protein into a solution, said solution comprising a plasticizing agent; (b) extruding said solution in an electric field; and (c) evaporating said solution under conditions suitable for formation of the fiber from the globular protein; thereby generating the fiber from the globular protein. - View Dependent Claims (20, 22, 23)
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21. (canceled)
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31-32. -32. (canceled)
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34-35. -35. (canceled)
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38-40. -40. (canceled)
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43-44. -44. (canceled)
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45. A fiber formed of a polymer of a globular protein, the globular protein having at least two functional SH groups capable of forming a disulfide bond between two molecules of the globular protein, wherein a secondary structure of the globular protein is maintained within said polymer.
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46-48. -48. (canceled)
Specification