TRANSDERMAL DELIVERY DEVICE AND METHOD

• US 20110238021A1
• Filed: 09/21/2009
• Published: 09/29/2011
• Est. Priority Date: 09/26/2008
• Status: Abandoned Application

• Current Assignee: Quikmed Pty., Ltd.
• Original Assignee: Quikmed Pty., Ltd.
• Inventors: Hillhouse, Suzana
• Application Number:
  US13/121,179
• Publication Number:
  US 20110238021A1
• Time in Patent Office: Days
• US Class Current: 604/307
• CPC Class Codes: A61K 31/167 having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
• CPC Class Codes: A61K 47/38 Cellulose; Derivatives thereof
• CPC Class Codes: A61K 9/7007 Drug-containing films, membranes or sheets A61K9/0041, A61K9/0043, A61K9/006, A61K9/0063 take precedence
• CPC Class Codes: A61K 9/7084 Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
• CPC Class Codes: A61M 35/006 using sponges, foams, absorbent pads or swabs as spreading means
• CPC Class Codes: A61P 23/02 Local anaesthetics

Abstract

A transdermal delivery device is provided for delivering at least one active therapeutic compound to rapidly induce a therapeutic effect, the device comprising: a pad for receiving a depot of the at least one therapeutic compound, the pad having a portion of material of high compression resistance; and the device also comprising a backing layer of greater cross-section than the pad. A method for rapidly reducing a therapeutic effect and a transdermal delivery but for delivering at least one therapeutic compound to rapidly induce a therapeutic effect are also provided.

Claims

1. A transdermal delivery device for delivering at least one active therapeutic compound to rapidly induce a therapeutic effect, the device comprising:

a pad for receiving a depot of the at least one therapeutic compound, the pad having a portion of material of high compression resistance, wherein the portion of material of high compression resistance is one layer of the pad, or the pad comprises an outer shell and an inner core and the outer shell is firmer and denser than the inner core; and

the device also comprising a backing layer of greater cross-section than the pad.

2. The device according to claim 1 further comprising an amount of the at least one therapeutic compound deposited within the pad.

3. The device according to claim 1 wherein the pad and the backing layer are fixed together.

4. The device according to claim 1 wherein the pad and backing layer are readily separable from one another.

8. The device according to claim 1 wherein the material of high compression resistance is a cotton material.

10. The device according to claim 1 wherein the pad comprises a layer of plastic foam.

11. The device according to claim 1 wherein the pad comprises a surface layer formed of perforated polyethelene film, nylon net, rayon net or cellulose unwoven cloth.

16. The device according to claim 1 wherein the backing layer has an adhesive surface for adhering to the person'"'"'s skin.

17. The device according to claim 1 wherein the backing layer is impermeable to the at least one active therapeutic compound.

18. The device according to claim 1 wherein the device further comprises an aperture in the backing layer through which an amount of the at least one therapeutic compound may be deposited in the pad.

25. The device according to claim 1 wherein the at least one therapeutic compound is any one or more anaesthetic compound.

27. The device according to claim 25 wherein the amine is lidocaine.

28. The device according to claim 27 wherein the lidocaine has a concentration in water of 0.001-4%.

29. The device according to claim 27 wherein the lidocaine has a concentration of approximately 2% by weight.

30. The device according to claim 1 further comprising a dye deposited within the pad for indicating the position that the device is placed on the person'"'"'s skin.

47. A transdermal delivery kit for delivering at least one therapeutic compound to rapidly induce a therapeutic effect, the kit comprising:

the transdermal delivery device as claimed in claim 1; and

an applicator for depositing the at least one therapeutic compound in the pad.

48. The kit according to claim 47 wherein the applicator comprises a syringe.

49. The kit according to claim 47 wherein the kit comprises an amount of the at least one therapeutic compound.

50. The kit according to claim 49 wherein the at least one therapeutic compound is stored within the applicator prior to use of the kit.

5-7. -7. (canceled)

9. The device according to claim 9 wherein the cotton material is blended with fibres selected from rayon, polyester or nylon, or mixtures of two or more of these fibres.

12. The device according to 1 wherein the outer shell is formed from perforated polyethylene film, nylon net, rayon net or cellulose unwoven cloth and the inner core includes a foam layer and a high compression resistant layer.

13-15. -15. (canceled)

19-24. -24. (canceled)

26. (canceled)

31. (canceled)

32. A transdermal delivery device for delivering at least one active therapeutic compound to rapidly induce a therapeutic effect, the device comprising:

a pad for receiving a depot of the at least one therapeutic compound, the pad having a portion of material of high compression resistance, and the pad comprising an outer shell and an inner core, the outer shell being firmer and denser than the inner core.

33-46. -46. (canceled)